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Showing 25–44 of 20 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Prolapse, Uterine Clear all
Completed Phase 4 Interventional Results available

Efficacy Study of Vaginal Mesh for Anterior Prolapse

NCT00557882
View directory record Official record
Conditions
Vaginal Prolapse, Uterine Prolapse, Cystocele, Pelvic Organ Prolapse
Interventions
synthetic polypropylene mesh
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
21 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional

Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy

NCT04440475
View directory record Official record
Conditions
Anesthesia, Local, Prolapse, Prolapse; Female, Prolapse, Vaginal, Prolapse; Vagina, Posthysterectomy, Pain, Postoperative
Interventions
TAP block
Procedure
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laparoscopic Versus Robotic Assisted Laparoscopic Sacrocolpopexy for Vaginal Prolapse

NCT00551993
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
robotic laparoscopic sacrocolpopexy, Laparoscopic Sacral Colpopexy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Preoperative Fiber on Postoperative Bowel Function

NCT04882995
View directory record Official record
Conditions
Constipation, Prolapse, Vaginal
Interventions
Psyillium fiber
Dietary Supplement
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Sep 29, 2026, 1:59 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Flat Polypropylene Mesh in the Treatment of Uterine and Recurrent or Advanced Pelvic Organ Prolapse

NCT06225375
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle® Flat Mesh
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Sep 29, 2026, 1:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using a Sheathed Speculum to Visualize and Access the Cervix In Women With Excessive Vaginal Tissue

NCT01409902
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2013 · Synced Sep 29, 2026, 1:59 AM EDT
Not listed Phase 4 Interventional

Pudendal Block Using Liposomal Bupivacaine vs. Standard Treatment During Sacrospinous Ligament Fixation

NCT03664986
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Liposomal Bupivacaine
Drug
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated May 9, 2021 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional

Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy

NCT01779739
View directory record Official record
Conditions
Sexual Function
Interventions
Perineorrhaphy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
19 Years to 105 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145
View directory record Official record
Conditions
Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
Interventions
Preoperative Pessary Use
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 29, 2026, 1:59 AM EDT
Completed No phase listed Observational

What is the Impact of the Presence of a Support Person on Informed Consent

NCT03966469
View directory record Official record
Conditions
Surgery, Knowledge, Attitudes, Practice, Prolapse, Vaginal, Urinary Incontinence
Interventions
Preoperative support person present, Patient Present Only
Other
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension

NCT02888093
View directory record Official record
Conditions
Pelvic Organ Prolapse, Cystocele, Uterine Prolapse
Interventions
Absorbent suture (polydioxanone) and Permanent suture (Gore-Tex CV2)
Device
Lead sponsor
Joseph Kowalski
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 1, 2019 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair

NCT00535301
View directory record Official record
Conditions
Cystocele, Uterine Prolapse, Urinary Incontinence
Interventions
grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
Device · Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
21 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Downey, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional

Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms

NCT03658395
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Laparoscopic Sacrocolopopexy, Posterior repair
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 29, 2026, 1:59 AM EDT
Terminated Phase 4 Interventional Results available

The ELEGANT Trial: Elevate Transvaginal Mesh vs. Anterior Colporrhaphy

NCT01497171
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Elevate Mesh, Anterior Colporrhaphy
Procedure
Lead sponsor
Emanuel Trabuco
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
5
States / cities
Roseville, California • Santa Clara, California • Stanford, California + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Sep 29, 2026, 1:59 AM EDT
Completed No phase listed Observational

Surgical Outcomes of Vaginal Prolapse Repair With Elevate

NCT01190618
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Not listed
Lead sponsor
Larry Sirls
Other
Eligibility
Female only
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Sep 29, 2026, 1:59 AM EDT
Active, not recruiting Not applicable Interventional Results available

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design

NCT02676973
View directory record Official record
Conditions
Visceral Prolapse
Interventions
Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 29, 2026, 1:59 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Uterine Artery Embolization and Pelvic Floor Symptoms

NCT00827645
View directory record Official record
Conditions
Leiomyoma, Incontinence, Prolapse
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Sep 29, 2026, 1:59 AM EDT
Completed No phase listed Observational Results available

Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study

NCT01378065
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP)
Interventions
Restorelle Direct Fix A&P
Device
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Baltimore, Maryland • Grand Rapids, Michigan • Marshall, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 29, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Study of Uterine Prolapse Procedures - Randomized Trial

NCT01802281
View directory record Official record
Conditions
Uterovaginal Prolapse
Interventions
Uterosacral ligament suspension, Uphold® LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Albuquerque, New Mexico + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 29, 2026, 1:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Robotic Assisted Laparoscopic Sacral Colpopexy Using Alyte Mesh

NCT01320644
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence, Mesh Erosion
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
21 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Sep 29, 2026, 1:59 AM EDT