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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

NCT04678115
View directory record Official record
Conditions
Blepharoptosis, Ptosis, Eyelid, Myasthenia Gravis, Stroke, Traumatic Brain Injury, Chronic Progressive External Ophthalmoplegia
Interventions
Magnetic Levator Prosthesis (MLP), Kinesiotape Frontalis Sling (KTFS)
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
5 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2025 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Phase 4 Interventional Results available

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

NCT02431897
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urogenital Prolapse, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Conjugated Estrogens Cream, Placebo Cream
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
48 Years and older · Female only
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
3
States / cities
Birmingham, Alabama • Providence, Rhode Island • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Promoting Effective Recovery From Labor Urinary Incontinence (PERL)

NCT00506116
View directory record Official record
Conditions
Urinary Incontinence, Pelvic Organ Prolapse, Perinatal Laceration, Second Stage Labor
Interventions
Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing, Data collection
Behavioral · Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2006
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 30, 2007 · Synced Jun 26, 2026, 1:57 PM EDT
Recruiting Not applicable Interventional

POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment

NCT06634459
View directory record Official record
Conditions
Pelvic Organ Prolapse, Prolapse
Interventions
Reia System, Standard of Care Pessary
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
9
States / cities
Birmingham, Alabama • Palo Alto, California • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 26, 2026, 1:57 PM EDT
Not yet recruiting Not applicable Interventional

Poly-L-Lactic Acid for Vulvovaginal Tissue Regeneration

NCT07544667
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP), Cystocele, Pelvic Floor Disorder
Interventions
Poly-L-Lactic Acid (Sculptra) injection, Placebo injection (sterile water)
Device · Other
Lead sponsor
Cassandra Kisby
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Not applicable Interventional

Treatment for Stress and Mixed Urinary Incontinence and Vaginal Vault Prolapse

NCT00223106
View directory record Official record
Conditions
Urinary Incontinence, Stress, Mixed Incontinence, Vaginal Vault Prolapse
Interventions
Vaginal Sling
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older · Female only
Enrollment
467 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Norwalk, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 26, 2015 · Synced Jun 26, 2026, 1:57 PM EDT
Withdrawn No phase listed Observational

Foley Catheterization Following Sacrocolpopexy

NCT01525498
View directory record Official record
Conditions
Pelvic Organ Prolapse, Catheter Infection, Urinary Retention
Interventions
Not listed
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 15, 2013 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Affixing Polypropylene Mesh Using Barbed Suture (Quill™ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)

NCT01551992
View directory record Official record
Conditions
Prolapse
Interventions
Quill suture vs. Interrupted suture
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2014 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery

NCT03052816
View directory record Official record
Conditions
Pain, Postoperative, Pelvic Organ Prolapse
Interventions
Ice T, Motrin/Percocet/Dilaudid for breakthrough
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jun 26, 2026, 1:57 PM EDT
Completed No phase listed Observational

Do Patients With Early Post Operative Recurrence of Pelvic Organ Prolapse Have a Genetic Predisposition?

NCT01614587
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Brow Enhancement Study

NCT01308593
View directory record Official record
Conditions
Brow Ptosis
Interventions
Juvederm XC, Botox
Device · Drug
Lead sponsor
Skin Care and Laser Physicians of Beverly Hills
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Jun 26, 2026, 1:57 PM EDT
Completed No phase listed Observational

Dynamic Magnetic Resonance Imaging Before and After Vaginal Prolapse Repair

NCT03315715
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VITOM Study: A Randomized, Controlled Trial.

NCT03120689
View directory record Official record
Conditions
Pelvic Organ Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Bulging of Vaginal Wall, Incontinence, Fistula
Interventions
Live Surgery using VITOM, Live Surgery without VITOM, Video viewing with VITOM, Video viewing with standard handheld high-definition camera
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laparoscopic Versus Robotic Assisted Laparoscopic Sacrocolpopexy for Vaginal Prolapse

NCT00551993
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
robotic laparoscopic sacrocolpopexy, Laparoscopic Sacral Colpopexy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Not applicable Interventional Results available

Permanent Versus Absorbable Colpopexy Trial

NCT02277925
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Polytetrafluoroethylene, Polydioxanone
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Augusta, Georgia • Chicago, Illinois • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Jun 26, 2026, 1:57 PM EDT
Completed No phase listed Observational

Characteristics Predictive of Pessary Success

NCT01123213
View directory record Official record
Conditions
All Patients Who Have Undergone a Pessary Fitting
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
Female only
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Jun 26, 2026, 1:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?

NCT02547155
View directory record Official record
Conditions
Urinary Retention, Uterine Prolapse
Interventions
Spinal anesthesia, General anesthesia
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Jun 26, 2026, 1:57 PM EDT
Terminated Not applicable Interventional Results available

Vaginal Hysterectomy vs Supracervical Hysterectomy at the Time of Sacrocolpopexy

NCT04797585
View directory record Official record
Conditions
Vaginal Hysterectomy, Laparoscopic Supracervical Hysterectomy
Interventions
Laparoscopic supracervical hysterectomy, Vaginal hysterectomy
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Patient Experience and Bowel Preparation for Transvaginal Surgical Management of Vaginal Prolapse

NCT01431040
View directory record Official record
Conditions
Value of the Bowel Preparation and Diet Change Versus no Intervention, Preoperative Bowel Regimen
Interventions
No bowel prep, Clear liquid diet and 2 Fleet's enemas
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 15, 2014 · Synced Jun 26, 2026, 1:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Vaginal Tactile Imaging in Assessment of Pelvic Floor Conditions

NCT02294383
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years and older · Female only
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Princeton, New Jersey • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Jun 26, 2026, 1:57 PM EDT
Not listed No phase listed Observational

Genetic Basis of Mitral Valve Prolapse

NCT01719211
View directory record Official record
Conditions
Mitral Valve Prolapse
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Jun 26, 2026, 1:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Telehealth Intervention to Increase Patient Preparedness for Surgery in Latinas

NCT06679621
View directory record Official record
Conditions
Incontinence, Prolapse
Interventions
Telehealth intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jun 26, 2026, 1:57 PM EDT
Completed Phase 2 Interventional Results available

Gentamicin Intravesical Efficacy for Infection of Urinary Tract

NCT04246996
View directory record Official record
Conditions
Postoperative Urinary Tract Infection, Pelvic Organ Prolapse, Stress Urinary Incontinence
Interventions
gentamicin sulfate, Catheter clamping only
Drug · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Jun 26, 2026, 1:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparing Vision Tests in a Virtual Reality Headset to Existing Analogues

NCT04714424
View directory record Official record
Conditions
Ptosis, Macular Degeneration, Ametropia
Interventions
Virtual Reality Headset
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Jun 26, 2026, 1:57 PM EDT