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ClinicalTrials.gov public records Last synced Jun 10, 2026, 1:49 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prolapse Pelvic Clear all
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Vaginal Estradiol Use in Pessary Care

NCT05458375
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence, Pessary Ulcer of Vagina, Vaginal Atrophy
Interventions
Estradiol vaginal cream
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Jun 10, 2026, 1:49 PM EDT
Terminated Not applicable Interventional

An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy With Laparoscopic Resection Rectopexy

NCT01595412
View directory record Official record
Conditions
Rectal Prolapse, Procidentia
Interventions
Laparoscopic Resection Rectopexy, Laparoscopic Ventral Rectopexy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
6
States / cities
Orlando, Florida • Tampa, Florida • Weston, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2017 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructive Surgery

NCT03040011
View directory record Official record
Conditions
Pelvic Organ Prolapse, Surgery, Postoperative Pain
Interventions
Dexamethasone, Bupivacaine, Bilateral Pudendal Nerve Block, Bilateral Levator Ani Muscle Injection, Saline
Drug · Procedure
Lead sponsor
Lauren Giugale, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2020 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Postoperative Opioid Consumption After Urogyneocologic Surgery

NCT03586219
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Opioid-specific educational patient pamphlets
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Anaheim, California • Irvine, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Jun 10, 2026, 1:49 PM EDT
Recruiting Not applicable Interventional

Accelerometer Measured Early Recovery After Prolapse Surgery

NCT07218016
View directory record Official record
Conditions
Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Patient Education
Interventions
Postoperative Exercise regimen
Behavioral
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
18 Years to 99 Years · Female only
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
7
States / cities
San Diego, California • Chicago, Illinois • Durham, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jun 10, 2026, 1:49 PM EDT
Completed No phase listed Observational

Urology Database to Evaluate Clinical Information and Improve Patient Care.

NCT00376298
View directory record Official record
Conditions
Incontinence, Prostate Cancer, Interstitial Cystitis, Urinary Retention, Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Kenneth Peters, MD
Other
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Evaluating the Optimal Volume Voided for Passage of a Backfill-Assisted Voiding Trial Following Urogynecologic Surgery

NCT05820139
View directory record Official record
Conditions
Voiding Dysfunction
Interventions
Control Group, Test Group
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Jun 10, 2026, 1:49 PM EDT
Completed No phase listed Observational

A Large Multi-Center Database of Women Who Have Had and Are Going to Have Surgical Correction of Their Pelvic Organ Prolapse Using the Gynecare Prolift System

NCT01134003
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
The Institute of Pelvic Medicine & Reconstructive Surgery, Allentown, Pennsylvania
Other
Eligibility
Female only
Timeline
2008 – 2009
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 30, 2010 · Synced Jun 10, 2026, 1:49 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

NCT07213635
View directory record Official record
Conditions
Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic, Postoperative Pain
Interventions
Bupivacaine-epinephrine, Normal saline
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Phase 4 Interventional Results available

Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery

NCT05658887
View directory record Official record
Conditions
Pelvic Organ Prolapse, Perioperative/Postoperative Complications
Interventions
Gabapentin, Gabapentin Placebo
Drug
Lead sponsor
Joseph Kowalski
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Jun 10, 2026, 1:49 PM EDT
Completed No phase listed Observational

Composite Graft Use in Abdominal Sacrocolpopexy Reduces Erosion Rates

NCT00581412
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2010 · Synced Jun 10, 2026, 1:49 PM EDT
Not listed No phase listed Observational

A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing

NCT01880918
View directory record Official record
Conditions
Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative, Colostomy, Ileostomy - Stoma, Rectal Prolapse, Intestinal Polyposis, Lymphoma, Endometriosis, Intestinal Volvulus
Interventions
Not listed
Lead sponsor
novoGI
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
3
States / cities
Atlamonte Springs, Florida • Port Charlotte, Florida • Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Not applicable Interventional Results available

Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery

NCT03048682
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence,Stress, Surgery
Interventions
Foley catheter - Early Voiding Trial, Foley catheter - Late Voiding Trial
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Weston, Florida • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Not applicable Interventional Results available

Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies

NCT01124916
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Robotic assisted laparoscopic abdominal sacrocolpopexy, Standard laparoscopic abdominal sacrocolpopexy
Procedure
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Los Angeles, California • Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 3, 2017 · Synced Jun 10, 2026, 1:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development Study Using Vaginal Tactile Imager

NCT01111916
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years to 65 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
2
States / cities
Princeton, New Jersey • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Jun 10, 2026, 1:49 PM EDT
Completed No phase listed Observational Results available

Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products

NCT00388947
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
AMS Prolapse Product
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
1,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Whitinsville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Jun 10, 2026, 1:49 PM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Post-Operative Pain Control Using Direct Continuous Bupivacaine Infusion After Pelvic Organ Prolapse Repair

NCT00695240
View directory record Official record
Conditions
Post-Operative Pain, Pelvic Organ Prolapse
Interventions
Continuous bupivacaine analgesia infusion (ON-Q PainBuster Post-Op Pain Relief System)
Device
Lead sponsor
St. Luke's Hospital, Kansas City, Missouri
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 10, 2008 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Catheter Management After Pelvic Reconstructive Surgery

NCT03071211
View directory record Official record
Conditions
Urinary Retention Postoperative, Pelvic Organ Prolapse
Interventions
Plug-unplug catheter management, Continuous drainage catheter management
Device
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Jun 10, 2026, 1:49 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Feasibility and Safety of Single Port Robot in Colorectal Procedures

NCT03700593
View directory record Official record
Conditions
Colon Cancer, Colon Polyp, Rectal Cancer, Diverticulitis, Prolapse, Rectal, Rectal Polyp, Inflammatory Bowel Diseases
Interventions
Single Port Robotic Colorectal Surgery
Device
Lead sponsor
Marks Colorectal Surgical Associates
Other
Eligibility
18 Years to 95 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Jun 10, 2026, 1:49 PM EDT
Completed No phase listed Observational

Validation Study for Robotic Surgery Simulator

NCT01618994
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Performing robotic supracervical hysterectomy
Procedure
Lead sponsor
Atlantic Health System
Other
Eligibility
Not listed
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Jun 10, 2026, 1:49 PM EDT
Terminated Not applicable Interventional Results available

Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse

NCT01648751
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Vaginal estrogen, Placebo
Drug
Lead sponsor
Pamela Moalli
Other
Eligibility
40 Years to 80 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms

NCT03658395
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Laparoscopic Sacrocolopopexy, Posterior repair
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Jun 10, 2026, 1:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Robotic Assisted Sacral Colpopexy : A Prospective Study Assessing Outcomes With Learning Curves

NCT01535833
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Device- Robotic sacral colpopexy
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Jun 10, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis

NCT01393171
View directory record Official record
Conditions
Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
Interventions
Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
Device · Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2018
U.S. locations
2
States / cities
Downey, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Jun 10, 2026, 1:49 PM EDT