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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prolapses, Vaginal Vault Clear all
Completed Not applicable Interventional Results available

The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study

NCT01166373
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Enrollment video, SSLF, ULS, PMT, Usual Care
Behavioral · Procedure · Other
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
18 Years and older · Female only
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
7
States / cities
Birmingham, Alabama • La Jolla, California • Maywood, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Jul 22, 2026, 4:56 AM EDT
Withdrawn Not applicable Interventional

Does Dexamethasone Administration Improve Recovery In Patients Undergoing Minimally Invasive Sacrocolpopexy?

NCT03094442
View directory record Official record
Conditions
Quality of Life, Pelvic Organ Prolapse, Prolapses, Vaginal Vault
Interventions
Dexamethasone, Normal saline
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 22, 2026, 4:56 AM EDT
Not listed Not applicable Interventional

Prophylactic Uterosacral Ligament Suspension at the Time of Hysterectomy for Prevention of Vaginal Vault Prolapse

NCT01364025
View directory record Official record
Conditions
Prolapse of Vaginal Vault After Hysterectomy
Interventions
uterosacral ligament suspension colpopexy bilateral
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
21 Years to 99 Years · Female only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Treatment for Stress and Mixed Urinary Incontinence and Vaginal Vault Prolapse

NCT00223106
View directory record Official record
Conditions
Urinary Incontinence, Stress, Mixed Incontinence, Vaginal Vault Prolapse
Interventions
Vaginal Sling
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older · Female only
Enrollment
467 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Norwalk, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 26, 2015 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension

NCT05688059
View directory record Official record
Conditions
Pelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, Cystocele
Interventions
Absorbable Suture and Permanent Suture
Other
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 12, 2025 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Restorelle® Y Mesh vs. Vertessa® Lite Y Mesh for Laparoscopic and Robotic-assisted Laparoscopic Sacrocolpopexy

NCT03681223
View directory record Official record
Conditions
Vaginal Vault Prolapse
Interventions
Vertessa® Lite Y mesh, Restorelle® Y mesh, Laparoscopic sacrocolpopexy, Robotic assisted laparoscopic sacrocolpopexy
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery

NCT05192954
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
LigaSureTM vessel sealing device
Device
Lead sponsor
Marlana McDowell
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy

NCT01840176
View directory record Official record
Conditions
Vaginal Vault Prolapse, Sexual Function
Interventions
McCall culdoplasty
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VITOM Study: A Randomized, Controlled Trial.

NCT03120689
View directory record Official record
Conditions
Pelvic Organ Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Bulging of Vaginal Wall, Incontinence, Fistula
Interventions
Live Surgery using VITOM, Live Surgery without VITOM, Video viewing with VITOM, Video viewing with standard handheld high-definition camera
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 4 Interventional Results available

Lessons on Urethral Lidocaine in Urodynamics

NCT04038099
View directory record Official record
Conditions
Urethra Issue, Pelvic Organ Prolapse, Urinary Incontinence, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Water-Based Vaginal Lubricant, lidocaine topical
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial

NCT00597935
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP)
Interventions
SSLF, ULS, PMT
Procedure · Behavioral
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
18 Years and older · Female only
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
9
States / cities
Birmingham, Alabama • Bellflower, California • La Jolla, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Jul 22, 2026, 4:56 AM EDT
Terminated No phase listed Observational

Exair® Versus Native Tissue Repair for Prolapse

NCT02162628
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Exair Prolapse Repair System, Total Native Tissue Repair
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
13
States / cities
Savannah, Georgia • Fort Wayne, Indiana • Dearborn, Michigan + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Jul 22, 2026, 4:56 AM EDT
Terminated Not applicable Interventional

Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse

NCT01594372
View directory record Official record
Conditions
Uterine Prolapse
Interventions
Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Jul 22, 2026, 4:56 AM EDT
Completed No phase listed Observational

Restorelle® Mesh Versus Native Tissue Repair for Prolapse

NCT02162615
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior, Native Tissue Repair Posterior
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
33
States / cities
Agoura Hills, California • Stanford, California • Denver, Colorado + 30 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Jul 22, 2026, 4:56 AM EDT
Not listed Not applicable Interventional

Intraperitoneal and Extraperitoneal Uterosacral Ligament Suspensions for Post-Hysterectomy Vaginal Vault Prolapse

NCT04172896
View directory record Official record
Conditions
Vaginal Vault Prolapse, Post-Hysterectomy Vaginal Vault Prolapse, Prolapse, Vaginal
Interventions
Intraperitoneal Uterosacral Ligament Suspension, Extraperitoneal Uterosacral Ligament Suspension
Procedure
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Jul 22, 2026, 4:56 AM EDT
Completed No phase listed Observational Results available

Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products

NCT00388947
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
AMS Prolapse Product
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
1,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Whitinsville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Jul 22, 2026, 4:56 AM EDT
Active, not recruiting Not applicable Interventional Results available

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design

NCT02676973
View directory record Official record
Conditions
Visceral Prolapse
Interventions
Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145
View directory record Official record
Conditions
Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
Interventions
Preoperative Pessary Use
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 4 Interventional Results available

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

NCT02431897
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urogenital Prolapse, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Conjugated Estrogens Cream, Placebo Cream
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
48 Years and older · Female only
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
3
States / cities
Birmingham, Alabama • Providence, Rhode Island • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Force of Stream to Retrograde Fill Voiding Trial After Vaginal Apex Suspension

NCT02753920
View directory record Official record
Conditions
Vaginal Apical Prolapse
Interventions
voiding trial, Foley catheter
Other · Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 95 Years · Female only
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2018 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Study of Uterine Prolapse Procedures - Randomized Trial

NCT01802281
View directory record Official record
Conditions
Uterovaginal Prolapse
Interventions
Uterosacral ligament suspension, Uphold® LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Albuquerque, New Mexico + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jul 22, 2026, 4:56 AM EDT