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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prolonged Sitting Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Interrupting Prolonged Sitting With Bouts of Physical Activity on Neurocognitive Function in Obesity

NCT04926207
View directory record Official record
Conditions
Obesity
Interventions
Physical Activity Breaks Intervention, Talking Breaks Control
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 64 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer Motivation Coaches, Social Media-based Support Group, and Behavior Change Strategies to Decrease Prolonged Sitting and Increase Moderate Exercise Snacks

NCT05360485
View directory record Official record
Conditions
Sedentary Behavior, Physical Inactivity
Interventions
MOV'D (Move Often eVery Day), Fitbit Self-Monitoring
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Jul 22, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Breaking Sitting with High-intensity Interval Training for Brain Health

NCT06243016
View directory record Official record
Conditions
Aging
Interventions
High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prolonged Sitting on Responses to Short-Term Exercise Training

NCT03352063
View directory record Official record
Conditions
Atherosclerosis, Metabolic Syndrome
Interventions
Prolonged sitting with exercise, Active walking with exercise.
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 35 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Interrupting Prolonged Sitting With Intermittent Exercise on Postprandial Lipemia

NCT03856606
View directory record Official record
Conditions
Metabolic Syndrome X, Atherosclerosis, Insulin Resistance, Hyperinsulinism, Glucose Metabolism Disorders, Metabolic Disease, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases, Cardiovascular Diseases
Interventions
Prolonged sitting without exercise, Prolonged sitting with interval exercise
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 40 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Breaking up Prolonged Sitting on Metabolic Flexibility

NCT02258438
View directory record Official record
Conditions
Health Behavior
Interventions
Uninterrupted sitting, Sitting + 1 bout of activity, Sitting + microbursts of activity
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
19 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interrupting Prolonged Sitting With Activity

NCT03256188
View directory record Official record
Conditions
Physical Activity
Interventions
Active classroom
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
8 Years to 12 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System

NCT04207333
View directory record Official record
Conditions
Sedentary Behavior, Cardiovascular Risk Factor, Mental Stress, Cognitive Change, Cerebrovascular Insufficiency
Interventions
Mental Arithmetic Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 59 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sedentary Behavior Interrupted - A Pilot Study of Acute Interventions on Prolonged Sitting

NCT02743286
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Frequent sit-to-stands, Walking breaks, Stand more
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Jul 22, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Defy The Odds: Exercise Forecasting and Motivation Strategies for Prolonged-Sitting Jobs

NCT07475130
View directory record Official record
Conditions
Prolonged Sitting
Interventions
Tailored messaging
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
40 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Standing Desks and Intermittent Walking on Cognitive Fatigue

NCT07576413
View directory record Official record
Conditions
Sitting Position, Overexertion From Maintaining Prolonged Standing Position, Walking
Interventions
Performance of cognitive tasks
Behavioral
Lead sponsor
Clarkson University
Other
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Potsdam, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 22, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Better Breaks: Strength Breaks vs Walk Breaks for Sedentary Behavior Breaks

NCT06909097
View directory record Official record
Conditions
Sedentary Employees
Interventions
Sitting breaks
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
30 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Prolonged Standing Compared to Prolonged Sitting on Postprandial Lipemia

NCT03089437
View directory record Official record
Conditions
Metabolic Syndrome, Atherosclerosis
Interventions
Prolonged Standing, Prolonged Sitting
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Jul 22, 2026, 2:01 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia

NCT04241081
View directory record Official record
Conditions
Sedentary Behavior, Hypertriglyceridemia
Interventions
Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Jul 22, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Interrupting Prolonged Sitting With ACTivity (InPACT) at Home Optimization Study

NCT06493214
View directory record Official record
Conditions
Adherence, Treatment, Physical Inactivity
Interventions
Physical activity
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
8 Years to 12 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 2:01 AM EDT