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ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:54 AM EDT

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Showing 241–264 of 334 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Prostheses Clear all
Completed Phase 3 Interventional Results available

Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis

NCT02740127
View directory record Official record
Conditions
Malignant Neoplasms of Male Genital Organs
Interventions
Caudal Nerve Block (CNB), Ropivacaine, Epinephrine, Decadron, Clonidine, Propofol, Phone Call
Procedure · Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Oct 24, 2026, 4:54 AM EDT
Completed No phase listed Observational

Total Knee Arthroplasty Guidance Systems Study

NCT02830997
View directory record Official record
Conditions
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Interventions
Stereotactic guidance system
Device
Lead sponsor
Ormonde M. Mahoney, MD
Other
Eligibility
45 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 24, 2026, 4:54 AM EDT
Terminated Phase 2 Interventional

CTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypass (CPB)

NCT00107666
View directory record Official record
Conditions
Coronary Disease, Heart Valve Diseases
Interventions
CTI-01 (ethyl pyruvate)
Drug
Lead sponsor
Critical Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
17
States / cities
Laguna Hills, California • Los Angeles, California • San Francisco, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2006 · Synced Oct 24, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional

Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction

NCT05674786
View directory record Official record
Conditions
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases, Vestibular Diseases, Sensation Disorders, Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy, Aminoglycoside Ototoxicity
Interventions
Labyrinth Devices MVI™ Multichannel Vestibular Implant System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
22 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Not listed Not applicable Interventional

Early Feasibility Study of the Percutaneous Osseointegrated Prosthesis (POP)

NCT02720159
View directory record Official record
Conditions
Traumatic Amputee
Interventions
Percutaneous Osseintegrated Prosthesis
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 25, 2016 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Comparison of Various Prosthetic Foot-Ankle Mechanisms

NCT05964855
View directory record Official record
Conditions
Transtibial Amputation - Unilateral
Interventions
MIT Variable Stiffness Prosthesis v1, MIT Variable Equilibrium Angle Prosthesis v1, MIT Sliding Beam Passive Prosthesis, Ossur Pro-Flex XC, Blatchford Elan Variable-Dampening Prosthesis, Ossur Proprio Variable Angle Prosthesis, MIT Variable Stiffness Prosthesis v2, MIT Variable Equilibrium Angle Prosthesis v2
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Burlington, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Active, not recruiting Not applicable Interventional

Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy

NCT04658693
View directory record Official record
Conditions
Lower Extremity Amputee, Diabetic Peripheral Neuropathy
Interventions
Implanted Multi contact stimulating electrode and intramuscular electromyography recording electrode
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Phase 3 Interventional Results available

Reverse Shoulder Prosthesis Study

NCT00764504
View directory record Official record
Conditions
Rotator Cuff Arthropathy, Failed Total Shoulder, Failed Hemi-arthroplasty
Interventions
Reverse Shoulder Prosthesis
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
25
States / cities
Glendale, California • Orange, California • Denver, Colorado + 21 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2011 · Synced Oct 24, 2026, 4:54 AM EDT
Completed No phase listed Observational

Reverse Shoulder Prosthesis Prospective Multi-Center Study

NCT01005446
View directory record Official record
Conditions
Rotator Cuff Deficiency, Shoulder Arthropathy, Failed Shoulder Replacement
Interventions
Encore Reverse Shoulder Prosthesis (RSP®)
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
60 Years and older
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
10
States / cities
Redwood City, California • Bradenton, Florida • Fort Lauderdale, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2021 · Synced Oct 24, 2026, 4:54 AM EDT
Not listed No phase listed Observational

Comparing Running-Specific and Traditional Prostheses During Running: Assessing Performance and Risk

NCT02875197
View directory record Official record
Conditions
Amputees, Running With Prosthesis
Interventions
Running on a treadmill at 6 different speeds
Other
Lead sponsor
Regis University
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Oct 24, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional

Can an Array of Micro-electrodes Implanted in a Human Nerve Record Neural Signals and Provide Feedback?

NCT05505513
View directory record Official record
Conditions
Amputation
Interventions
percutaneous Utah Slanted Electrode Arrays (pUSEAs)
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Phase 2 Interventional Results available

Humacyte's HAV for Femoro-Popliteal Bypass in Patients With PAD

NCT02887859
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Human Acellular Vessel (HAV)
Biological
Lead sponsor
Humacyte, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
5
States / cities
San Francisco, California • Boston, Massachusetts • Flint, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional

PRIMA US-Feasibility Study in Atrophic Dry AMD

NCT03392324
View directory record Official record
Conditions
Dry Age-related Macular Degeneration
Interventions
PRIMA
Device
Lead sponsor
Science Corporation
Industry
Eligibility
60 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
3
States / cities
Palo Alto, California • Miami, Florida • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Assessment of a Hybrid Pump for Vacuum Suspension of Prosthetic Sockets for Persons With Lower Limb Loss to Characterize the Effects of Added Movement on Socket-reaction Torques

NCT04230512
View directory record Official record
Conditions
Amputation
Interventions
Pump prototype
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Head-Mounted Vibrotactile Prosthesis for Patients With Chronic Postural Instability

NCT03330262
View directory record Official record
Conditions
Vestibular Disorder, Dizziness
Interventions
BALCAP prosthesis
Device
Lead sponsor
Barron Associates, Inc.
Industry
Eligibility
21 Years to 89 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 24, 2026, 4:54 AM EDT
Active, not recruiting No phase listed Observational

Database Retrieval for the Comprehensive Shoulder

NCT03409718
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Avascular Necrosis, Rheumatoid Arthritis, Prior Failed Revision, Correction of Functional Deformity, Fracture of Proximal End of Humerus, Cuff Tear Arthropathy
Interventions
Biomet Comprehensive Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Veteran Ear Acupuncture Pilot Project

NCT04208659
View directory record Official record
Conditions
Chronic Pain Syndrome, Pain, Fibromyalgia, Low Back Pain, Neuropathic Pain, Neuropathy, Painful, Musculoskeletal Pain, Chronic Pain
Interventions
Self-administration of auricular acupuncture without prosthesis, Self-administration of auricular acupuncture with prosthesis
Procedure
Lead sponsor
Chillicothe VA Medical Center
Federal
Eligibility
18 Years to 120 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chillicothe, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Phase 1 Interventional Results available

Head-Mounted Vibrotactile Prosthesis for Patients With Chronic Postural Instability

NCT00889824
View directory record Official record
Conditions
Dizziness
Interventions
balance prosthesis
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 85 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 15, 2016 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Determining the Potential Benefit of Powered Prostheses

NCT02828982
View directory record Official record
Conditions
Unilateral Traumatic Amputation, Amputation, Traumatic
Interventions
Powered ankle prosthesis, Dynamic Response Foot
Device
Lead sponsor
Deanna H Gates
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Biomechanical Assessment of Gait in Lower-Extremity-Amputees

NCT01332123
View directory record Official record
Conditions
Prosthesis User
Interventions
Alignment perturbations
Device
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 9, 2016 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Lower Limb Prostheses for Individuals Who Carry Infants, Toddlers, and Other Loads

NCT07159490
View directory record Official record
Conditions
Amputation, Prosthesis User
Interventions
Standard-of-care prosthetic foot, Standard-of-care prosthetic foot with heel-stiffening wedge, Standard-of-care prosthetic foot of one category greater stiffness, Dual keel prosthetic foot, Powered ankle-foot
Device
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Phase 3 Interventional Results available

Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee Replacement

NCT01094886
View directory record Official record
Conditions
Arthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Thromboembolism
Interventions
Rivaroxaban
Drug
Lead sponsor
Ortho-McNeil Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
5
States / cities
Denver, Colorado • Hollywood, Florida • Tamarac, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 24, 2026, 4:54 AM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement

NCT06489431
View directory record Official record
Conditions
Erectile Dysfunction, Penile Prosthesis; Complications, Infection or Inflammation
Interventions
Chlorhexidine, Gentamicin, Rifampin
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Mountain View, California • Chicago, Illinois • Des Plaines, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 24, 2026, 4:54 AM EDT
Completed Phase 3 Interventional

Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY)

NCT01479283
View directory record Official record
Conditions
Infection, Bone Neoplasms
Interventions
24-Hour Prophylactic Cefazolin* Antibiotic Regimen, 5-Days Prophylactic Cefazolin* Antibiotic Regimen
Drug
Lead sponsor
McMaster University
Other
Eligibility
12 Years and older
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
34
States / cities
Little Rock, Arkansas • Los Angeles, California • Redwood City, California + 26 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 24, 2026, 4:54 AM EDT