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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:17 AM EDT

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Showing 49–72 of 333 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Prostheses Clear all
Completed Not applicable Interventional Results available

Digital Weight Bearing Shape Capture Socket Technology

NCT05749952
View directory record Official record
Conditions
Amputation, Prosthesis User, Residual Limbs
Interventions
Symphonie Aqua Digital System mediated sh
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 23, 2026, 4:17 AM EDT
Completed No phase listed Observational Results available

Retrospective Encore Reverse Shoulder Prosthesis Study

NCT00765037
View directory record Official record
Conditions
Rotator Cuff Deficiency, Glenohumeral Arthritis
Interventions
Encore Reverse Shoulder Prosthesis
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 25, 2010 · Synced Oct 23, 2026, 4:17 AM EDT
Completed Not applicable Interventional

SpeakFree Heat and Moisture Exchanger (HME)

NCT05349487
View directory record Official record
Conditions
Laryngeal Cancer, Laryngectomy
Interventions
SpeakFree HME Hands Free Valve, Digital Occlusion, Digital Depression HME
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 23, 2026, 4:17 AM EDT
Recruiting Not applicable Interventional

Regulatory Clearance of the Glide Control Strategy for Upper Limb Prostheses

NCT06539936
View directory record Official record
Conditions
Amputation, Upper Limb
Interventions
Glide, Direct Control
Device
Lead sponsor
Infinite Biomedical Technologies
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Redondo Beach, California
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 23, 2026, 4:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing Intact and Residual Amputated Muscle

NCT06182202
View directory record Official record
Conditions
Amputation
Interventions
Powered Prosthesis
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 23, 2026, 4:17 AM EDT
Active, not recruiting Early Phase 1 Interventional

Feasibility Study Evaluating the Safety and Effectiveness of Magnetic Bead Tracking System When Used With a Bionic External Prosthesis

NCT07195461
View directory record Official record
Conditions
Transtibial Amputee, Transtibial Amputation
Interventions
Magnetic Bead Tracking System
Device
Lead sponsor
MuscleMetrix, LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 23, 2026, 4:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

In Vivo Determination of 3D Patellofemoral Mechanics

NCT01290627
View directory record Official record
Conditions
Arthroplasty Replacement Knee, Knee Prosthesis
Interventions
Subjects implanted with DePuy LCS PS RP TKA, Subjects implanted with DePuy Sigma PS RP TKA
Device
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
20 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
4
States / cities
Denver, Colorado • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Oct 23, 2026, 4:17 AM EDT
Terminated Not applicable Interventional

Micro-Electrodes Implanted in a Human Nerve

NCT02034461
View directory record Official record
Conditions
Amputations, Peripheral Nerve Injury, Spinal Cord Injury
Interventions
Utah Slanted Electrode Array
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Oct 23, 2026, 4:17 AM EDT
Not listed Not applicable Interventional

Air Barrier System for the Prevention of Prosthesis-related Infections

NCT02376153
View directory record Official record
Conditions
Prosthesis-Related Infections
Interventions
ABS deployed and active, ABS deployed and NOT active
Device
Lead sponsor
Nimbic Systems, LLC
Industry
Eligibility
21 Years and older
Enrollment
816 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Oct 23, 2026, 4:17 AM EDT
Active, not recruiting No phase listed Observational

Clinical Evaluation of Implants Restored With Advanced Lithium Disilicate Screw-retained Crowns

NCT05752539
View directory record Official record
Conditions
Dental Prosthesis Failure, Dental Prosthesis Complication
Interventions
CEREC System by Dentsply Sirona
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 23, 2026, 4:17 AM EDT
Active, not recruiting Not applicable Interventional

A Clinical Trial Comparing the BAGUERA C to the Marketed Mobi-C® for the Treatment of Cervical Disc Disease at 2 Contiguous Levels

NCT04564885
View directory record Official record
Conditions
Cervical Disc Disease
Interventions
BAGUERA®C Cervical Disc Prosthesis, Mobi-C Cervical Disc
Device
Lead sponsor
Spineart USA
Industry
Eligibility
22 Years to 69 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
26
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Laguna Hills, California + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 23, 2026, 4:17 AM EDT
Completed No phase listed Observational

Total Knee Arthroplasty Guidance Systems Study

NCT02830997
View directory record Official record
Conditions
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Interventions
Stereotactic guidance system
Device
Lead sponsor
Ormonde M. Mahoney, MD
Other
Eligibility
45 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 23, 2026, 4:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating Mobility Interventions in the Real World

NCT04275973
View directory record Official record
Conditions
Lower Limb Amputation, Drop Foot
Interventions
Lower limb prostheses, Orthoses for Drop-foot
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 23, 2026, 4:17 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Postoperative Function Following Partial and Total Knee Replacement

NCT00492219
View directory record Official record
Conditions
Osteoarthritis, Post-traumatic Arthritis
Interventions
Vanguard M fixed-bearing or Oxford mobile-bearing prostheses, Total Knee Replacement
Device
Lead sponsor
New Lexington Clinic
Other
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 19, 2012 · Synced Oct 23, 2026, 4:17 AM EDT
Not listed Not applicable Interventional

Safety and Effectiveness of the CustomFlex Artificial Iris Prosthesis for the Treatment of Iris Defects

NCT01860612
View directory record Official record
Conditions
Full Aniridia, Partial Aniridia
Interventions
Artificial Iris (CustomFlex)
Device
Lead sponsor
Clinical Research Consultants, Inc.
Industry
Eligibility
3 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
13
States / cities
Los Angeles, California • Atlanta, Georgia • Indianapolis, Indiana + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Oct 23, 2026, 4:17 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Clinical Study of a 3D Shaded Zirconia for Chairside CAD/CAM Restorations

NCT06713577
View directory record Official record
Conditions
Dental Prosthesis Failure, Dental Prosthesis Complication
Interventions
CEREC Cercon 4D
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2031
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 23, 2026, 4:17 AM EDT
Completed Not applicable Interventional Results available

Comparison of Prosthetic Feet for People With Syme's Amputation (XF Symes Study)

NCT04086641
View directory record Official record
Conditions
Amputation, Artificial Limb
Interventions
Crossover foot, Energy Storing Foot
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 14, 2020 · Synced Oct 23, 2026, 4:17 AM EDT
Withdrawn Not applicable Interventional

RETINA IMPLANT Alpha AMS in Blind Patients With Retinitis Pigmentosa

NCT03629899
View directory record Official record
Conditions
Retinitis Pigmentosa
Interventions
RETINA IMPLANT Alpha AMS
Device
Lead sponsor
Wills Eye
Other
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 10, 2019 · Synced Oct 23, 2026, 4:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Functional Performance of Voluntary Opening and Closing Body Powered Prostheses

NCT02136238
View directory record Official record
Conditions
Upper Limb Amputation
Interventions
Hosmer 5XA voluntary opening hook, TRS Grip 3 voluntary closing hook
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced Oct 23, 2026, 4:17 AM EDT
Active, not recruiting Not applicable Interventional

Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy

NCT04658693
View directory record Official record
Conditions
Lower Extremity Amputee, Diabetic Peripheral Neuropathy
Interventions
Implanted Multi contact stimulating electrode and intramuscular electromyography recording electrode
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 23, 2026, 4:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

NCT05796908
View directory record Official record
Conditions
Arthritis, Unstable Radial Head, Proximal Radioulnar Joint Instability, Decreased Motion at the Proximal Radioulnar Joint and/or the Radio-humeral Joint
Interventions
Aptis PRUJ Prosthesis
Device
Lead sponsor
Aptis Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
7
States / cities
Carmel, Indiana • Louisville, Kentucky • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 23, 2026, 4:17 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

StaphVAX Immunogenicity in Orthopedic Implant Patients

NCT00211926
View directory record Official record
Conditions
Staphylococcal Infections, Joint Prosthesis
Interventions
S. aureus Type 5 & 8 Capsular Polysaccharide Conjugate, placebo
Biological
Lead sponsor
Nabi Biopharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 4, 2008 · Synced Oct 23, 2026, 4:17 AM EDT
Completed Not applicable Interventional Results available

No Power Bionic Lower Extremity Prosthesis

NCT04070105
View directory record Official record
Conditions
Amputation, Amputation, Traumatic, Amputation; Traumatic, Leg, Lower
Interventions
Compliant Adaptive Energy Storage and Return Foot, AllPro
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 23, 2026, 4:17 AM EDT
Terminated Phase 4 Interventional

Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty

NCT01196169
View directory record Official record
Conditions
Staphylococcal Infections, Methicillin-resistant Staphylococcus Aureus
Interventions
Daptomycin, Vancomycin
Drug
Lead sponsor
Mountain Home Research & Education Corporation
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Johnson City, Tennessee • Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 3, 2014 · Synced Oct 23, 2026, 4:17 AM EDT