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ClinicalTrials.gov public records Last synced Oct 23, 2026, 9:29 PM EDT

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Showing 193–216 of 334 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Prostheses Clear all
Withdrawn No phase listed Observational

A Study of Participants Undergoing Radial Head Replacement Using the DePuy Synthes Radial Head Replacement System for Partial Replacement of the Elbow Joint

NCT05415592
View directory record Official record
Conditions
Radial Head Fractures
Interventions
DePuy Synthes Radial Head Replacement System
Device
Lead sponsor
DePuy Synthes Products, Inc.
Industry
Eligibility
22 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
3
States / cities
Cleveland, Ohio • Eugene, Oregon • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physiologic Range of Step-by-step Variations in Lower Limb Prosthesis Forces During Walking

NCT02234505
View directory record Official record
Conditions
Trans-tibial Limb Loss
Interventions
Prosthetic alignment perturbation
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2015 · Synced Oct 23, 2026, 9:29 PM EDT
Enrolling by invitation Not applicable Interventional

Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

NCT06406751
View directory record Official record
Conditions
Dental Prosthesis
Interventions
MI Paste
Device
Lead sponsor
University of Iowa
Other
Eligibility
65 Years to 105 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 23, 2026, 9:29 PM EDT
Enrolling by invitation Not applicable Interventional

Sonomyographic Upper Limb Prosthetics: A New Paradigm

NCT05376332
View directory record Official record
Conditions
Amputation, Prosthesis User
Interventions
Sonomyographic Prosthesis, Myoelectric direct control prosthesis, Myoelectric pattern recognition prosthesis
Device
Lead sponsor
George Mason University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Myoelectric Game Training and Outcomes

NCT04354493
View directory record Official record
Conditions
Amputation, Prosthesis User, Prosthesis
Interventions
Myo-electric Gaming Interface
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Holliston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional

An Osseointegrated Transfemoral Prosthesis Offering Long-Term Bi-Directional Efferent-Afferent Neural Transmission

NCT07615465
View directory record Official record
Conditions
Transfemoral Amputation
Interventions
MIT Powered Knee Prosthesis
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
22 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 23, 2026, 9:29 PM EDT
Recruiting No phase listed Observational

Pro APP Prosthetic Outcome Registry

NCT06210620
View directory record Official record
Conditions
Amputation
Interventions
Not listed
Lead sponsor
Össur Iceland ehf
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 23, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

Stiffness and Low Dose Irradiation RCT

NCT07767097
View directory record Official record
Conditions
Arthrofibrosis of Knee
Interventions
Low-Dose External Beam Irradiation, Hinged Revision Total Knee Arthroplasty
Radiation · Procedure
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Targeted Reinnervation for Neuromas as a Means to Improve Prosthesis Control in Major Limb Amputation

NCT02316262
View directory record Official record
Conditions
Neuroma, Pain, Prosthesis User, Prosthesis Failure
Interventions
Targeted Muscle Reinnervation
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
6
States / cities
Chicago, Illinois • Bethesda, Maryland • Columbus, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2018 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

LDR Spine USA Mobi-C(R) Cervical Disc Prosthesis IDE

NCT00389597
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Cervical Artificial Disc
Device
Lead sponsor
LDR Spine USA
Industry
Eligibility
18 Years to 69 Years
Enrollment
599 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
24
States / cities
Phoenix, Arizona • Escondido, California • Laguna Hills, California + 21 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2017 · Synced Oct 23, 2026, 9:29 PM EDT
Withdrawn Not applicable Interventional

Evaluation of a Multi-electrode Prosthesis Control System for Real-world Tasks Performance in Individuals With Upper Limb Transradial Amputation

NCT07071584
View directory record Official record
Conditions
Upper Limb Amputation Below Elbow
Interventions
Cutaneous Prosthesis Control System
Device
Lead sponsor
Phantom Neuro Inc.
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Buffalo, New York • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Alternative Prosthetic Alignments on Sit-to-Stand Proficiency in Transtibial Amputees

NCT04657614
View directory record Official record
Conditions
Amputation Balance Prosthesis
Interventions
Neutral Alignment, Anterior Alignment, Posterior Alignment
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Oct 23, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

Transdermal Compress IDE Study

NCT06134167
View directory record Official record
Conditions
Prosthesis and Implants
Interventions
Transdermal Compress Device
Device
Lead sponsor
Balmoral Medical company
Industry
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
9
States / cities
Sacramento, California • Aurora, Colorado • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees

NCT02240186
View directory record Official record
Conditions
Lower Limb Amputation Above Knee (Injury)
Interventions
Microprocessor Knee (MPK), Non-Microprocessor Knee (NMPK)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
55 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty

NCT03274466
View directory record Official record
Conditions
Surgical Wound, Revision Total Knee Arthroplasty, Wounds and Injuries, Joint Disease, Musculoskeletal Disease, Prosthesis-Related Infections, Infection, Postoperative Complications, Pathologic Processes
Interventions
Closed Incision Negative Pressure Therapy (ciNPT), Standard of Care Dressing
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
22 Years and older
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
17
States / cities
Weston, Florida • Tucker, Georgia • New Orleans, Louisiana + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 23, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

NCT07078383
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Aneurysm and Dissection, Aortic Diseases, Aneurysm of Aorta, Thoracic, Aneurysmal Disease, Aorta, Thoracic Pathologies
Interventions
Rapidlink
Device
Lead sponsor
Vascutek Ltd.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
15
States / cities
Los Angeles, California • Aurora, Colorado • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Active Powered Prosthesis (APEX) for Spinal Cord Injury

NCT03696927
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Active Powered Prosthesis (APEX) for Spinal Cord Injury
Device
Lead sponsor
AbiliTech Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Oct 23, 2026, 9:29 PM EDT
Completed No phase listed Observational Results available

PROPPER Prospective Registry of Outcomes With Penile Prosthesis

NCT01383018
View directory record Official record
Conditions
Erectile Dysfunction, Impotence
Interventions
AMS Penile Prosthesis Devices
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older · Male only
Enrollment
1,457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
10
States / cities
Homewood, Alabama • Mountain View, California • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 23, 2026, 9:29 PM EDT
Recruiting Phase 1 Interventional

Towards Efficient Personalization of Computerized Lower Limb Prostheses Via Reinforcement Learning in a Clinical Setup - Group 1

NCT07204925
View directory record Official record
Conditions
Transfemoral Amputation
Interventions
RISE guided personalization of prosthetic legs by tuning experts, RISE guided personalization of prosthetic legs by prosthetists, Manual personalization of the prosthetic leg by tuning experts
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Phase 2 Interventional

Dentures and Dental Implants in Treating Patients Undergoing Surgery for Mouth Cancer

NCT00006341
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Implant
Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
35 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2003
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Oct 23, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Moisture Management Liner Effectiveness Study

NCT04427007
View directory record Official record
Conditions
Amputation Stumps, Amputees, Amputation, Lower Limb Deformities, Congenital, Prosthesis User, Prosthesis
Interventions
Moisture Management Liner, Control Liner
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Holliston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2025 · Synced Oct 23, 2026, 9:29 PM EDT
Withdrawn Not applicable Interventional

An Osseoanchored Percutaneous Prosthesis Study Evaluating Stable Neural Signal Transmission in Subjects With Transhumeral Amputations

NCT03957226
View directory record Official record
Conditions
Amputation Neuroma, Amputation, Prosthesis User
Interventions
e-OPRA (electronic-Osseoanchored Prosthese for the Rehabilitation of Amputees)
Device
Lead sponsor
University of Michigan
Other
Eligibility
22 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 23, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

Caesar Foot Take-Home Validation Testing

NCT07075198
View directory record Official record
Conditions
Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Interventions
Caesar Foot
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 23, 2026, 9:29 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Wound Healing Following Penile Prosthesis Implant

NCT05196191
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
VIAGENEX Max, Hibiclens wash
Biological · Procedure
Lead sponsor
VIVEX Biologics, Inc.
Industry
Eligibility
30 Years to 70 Years · Male only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2024 · Synced Oct 23, 2026, 9:29 PM EDT