Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:31 AM EDT

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Showing 193–216 of 342 matching trials from the live ClinicalTrials.gov search.
Conditions
Ocular Injury, Optic Nerve Diseases, Photoreceptor Degeneration, Blindness,Acquired
Interventions
WFMA - wireless floating microelectrode array
Device
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
19 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

EmPOWERing Active Seniors With Energy

NCT02958553
Conditions
Amputation
Interventions
emPOWER Ankle, Subject's own passive prosthesis
Device
Lead sponsor
Otto Bock Healthcare Products GmbH
Industry
Eligibility
55 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Conditions
Prosthesis Use, Limb Loss
Interventions
Modular Prosthetic Limb
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
Interventions
Ceramax Acetabular System
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
Not listed
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
12
States / cities
Sacramento, California • Denver, Colorado • Fort Collins, Colorado + 8 more
Conditions
Prosthesis-Related Infections, Arthroplasty
Interventions
Betadine Lavage, Saline Lavage
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
2
States / cities
Chicago, Illinois • Winfield, Illinois
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Clinical Trial of Tensegrity Prosthetics K3 Promoter Foot Prosthesis

NCT00888199
Conditions
Amputation
Interventions
Experimental prosthetic foot (K3 Promoter)
Device
Lead sponsor
Tensegrity Prosthetics
Industry
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Boulder, Colorado
Conditions
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis, Post-traumatic Arthritis
Interventions
Ascension® MCP Finger Implant
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
9
States / cities
Tucson, Arizona • Bloomington, Indiana • Carmel, Indiana + 5 more
Recruiting Not applicable Interventional

Vestibular Implantation in Older Adults

NCT05676944
Conditions
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases, Vestibular Diseases, Sensation Disorders, Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy, Presbyvestibulopathy, Aminoglycoside Ototoxicity
Interventions
Labyrinth Devices MVI™ Multichannel Vestibular Implant System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Transfemoral Amputees
Interventions
Vanderbilt Powered Knee-Ankle Prosthesis, Microprocessor (MP) Knee Prosthesis
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Osteoarthritis
Interventions
Total and Unicompartment Knee Replacement
Device
Lead sponsor
Medacta USA
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Leesburg, Florida
Conditions
Ankle Rheumatoid Arthritis, Arthritis of Ankle, Failure, Prosthesis
Interventions
Not listed
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2031
U.S. locations
2
States / cities
Jacksonville, Florida • Durham, North Carolina
Conditions
Aortic Valve Stenosis, Aortic Valve Regurgitation, Prosthesis Failure
Interventions
Doppler-echocardiography, Invasive hemodynamic measurements
Procedure
Lead sponsor
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Other
Eligibility
18 Years and older
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
San Francisco, California • Hollywood, Florida • Royal Oak, Michigan + 3 more
Completed Not applicable Interventional Results available

Post-Approval Study for the FLAIR Endovascular Stent Graft

NCT00677235
Conditions
Stenosis of Vascular Prosthetic Devices, Implants and Grafts
Interventions
FLAIR Endovascular Stent Graft, PTA
Device · Procedure
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Bamberg, South Carolina
Conditions
Amputation; Traumatic, Hand
Interventions
Point Powered partial hand prosthetic system
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Aurora, Colorado • Broomfield, Colorado • Lafayette, Colorado
Conditions
Osteoarthritis Shoulder, Rheumatoid Arthritis, Oncology
Interventions
Not listed
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Neuroma, Pain, Prosthesis User, Prosthesis Failure
Interventions
Targeted Muscle Reinnervation
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
6
States / cities
Chicago, Illinois • Bethesda, Maryland • Columbus, Ohio + 3 more
Recruiting Not applicable Interventional

Stiffness and Low Dose Irradiation RCT

NCT07767097
Conditions
Arthrofibrosis of Knee
Interventions
Low-Dose External Beam Irradiation, Hinged Revision Total Knee Arthroplasty
Radiation · Procedure
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Salt Lake City, Utah
Conditions
Joint Prosthesis
Interventions
68-Gallium citrate PET/CT scan, 18F FDG PET/CT scan
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Newark, New Jersey
Conditions
Transfemoral Amputation, Limb Loss, Limb Absence
Interventions
Powered prosthetic knee joint, Conventional microprocessor-controlled prosthetic knee joint
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Wearing a Powered Ankle-Foot Prosthesis on Amputee Walking

NCT00869947
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Powered ankle-foot prosthesis, No device
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Prosthesis User, Amputation, Upper Limb Amputation at the Wrist, Upper Limb Amputation Above Elbow (Injury), Upper Limb Amputation Below Elbow (Injury)
Interventions
Qualitative Analysis
Other
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Limb Deficiencies, Pediatric ALL
Interventions
iFIT prosthesis
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
3 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

Functional Performance Evaluation of NU-FlexSIV Socket

NCT02678247
Conditions
Amputation, Artificial Limbs
Interventions
Northwestern University Flexible Sub-Ischial Vacuum Socket, Ischial Containment Socket
Device
Lead sponsor
Northwestern University
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
3
States / cities
Chicago, Illinois • Oakbrook Terrace, Illinois
Conditions
Upper Limb Amputation Below Elbow
Interventions
Cutaneous Prosthesis Control System
Device
Lead sponsor
Phantom Neuro Inc.
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Buffalo, New York • Austin, Texas