Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 30, 2026, 4:11 PM EDT

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Showing 25–30 of 30 matching trials from the live ClinicalTrials.gov search.
Conditions
Prosthetic Joint Infection
Interventions
TRL1068, a human monoclonal antibody
Drug
Lead sponsor
Trellis Bioscience LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
9
States / cities
Birmingham, Alabama • Los Angeles, California • Santa Monica, California + 6 more
Conditions
Aseptic Loosening of Prosthetic Joint, Instability of Prosthetic Joint, Reimplantation for Periprosthetic Joint Infection, Femoral Revision Indicated, Tibial Component Revision
Interventions
Constrained Condylar bearing, posterior stabilized bearing
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2038
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
Interventions
TRL1068 (calpurbatug), a human monoclonal antibody, DAIR
Drug · Procedure
Lead sponsor
Trellis Bioscience LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
11
States / cities
Gilbert, Arizona • Los Angeles, California • Jacksonville, Florida + 8 more
Conditions
Prosthetic-joint Infection
Interventions
PLG0206, Placebo
Drug
Lead sponsor
Peptilogics
Industry
Eligibility
18 Years to 85 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
16
States / cities
Sarasota, Florida • Tamarac, Florida • Shreveport, Louisiana + 13 more
Conditions
Prosthetic Joint Infection of the Knee
Interventions
Static Antibiotic Spacer Surgical Implant, Articulating Antibiotic Spacer Surgical Implant
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Prosthetic Joint Infection
Interventions
Calprotectin test
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Weston, Florida • Cleveland, Ohio