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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:23 AM EDT

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Showing 73–96 of 184 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Psychological Distress Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Aromatherapy to Address Psychological Distress in Emergency Department Patients.

NCT07328412
View directory record Official record
Conditions
Aromatherapy, Anxiety, Stress, Emergency Department
Interventions
Lavender Aromatherapy, Unscented Aromatherapy
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yoga for Stress and Mental Health

NCT01652807
View directory record Official record
Conditions
Physiological Stress, Psychological Distress, Depression, Anxiety
Interventions
Hatha Yoga
Behavioral
Lead sponsor
Southern Methodist University
Other
Eligibility
25 Years to 45 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Oct 20, 2026, 1:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stress Related Disorders in Family Members of COVID-19 Patients Admitted to the ICU

NCT04476914
View directory record Official record
Conditions
Respiratory Failure, SARS-CoV 2, Corona Virus Infection, Post Intensive Care Unit Syndrome, Family Members, Post Traumatic Stress Disorder, Anxiety, Depression
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
9
States / cities
Aurora, Colorado • New Orleans, Louisiana • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Results available

A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers

NCT04816708
View directory record Official record
Conditions
Emotional Distress, Burnout, Professional, Stress, Job, Anxiety, Depressive Symptoms
Interventions
LIFT Mindfulness
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional

Interventions to Decrease Financial Toxicity

NCT05939440
View directory record Official record
Conditions
Cancer, Breast, Cancer Colorectal, Cancer, Ovarian, Cervical Cancer, Uterine Cancer, Vulvar Cancer
Interventions
Proactive Cost of Care (P-COC) intervention, Usual Care
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 20, 2026, 1:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examine the Psychosocial Impacts of COVID-19 Pandemic.

NCT05052333
View directory record Official record
Conditions
Psychosocial Impacts, COVID-19 Pandemic
Interventions
Not listed
Lead sponsor
University of Otago
Other
Eligibility
18 Years and older
Enrollment
2,574 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 20, 2026, 1:23 AM EDT
Completed No phase listed Observational

Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers

NCT04339790
View directory record Official record
Conditions
Healthy Volunteer, Mood Disorder, Anxiety Disorder, Preexisting Medical Condition
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
3,655 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Results available

Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab

NCT01393821
View directory record Official record
Conditions
Dermatologic Complications, Malignant Neoplasm, Pain
Interventions
menadione topical lotion, placebo, questionnaire administration, management of therapy complications
Drug · Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Phoenix, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Results available

Improving Quality of Life for Veterans With Stroke and Psychological Distress

NCT03645759
View directory record Official record
Conditions
Stroke, Depression, Anxiety
Interventions
I'm Whole, Education + usual care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Three-Principles Approach for Incarcerated Adults

NCT04747704
View directory record Official record
Conditions
Psychological Distress, Recidivism
Interventions
Three Principles Counseling
Behavioral
Lead sponsor
Pacific University
Other
Eligibility
21 Years to 65 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Hillsboro, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 29, 2022 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Results available

Caregivers' and Cancer Survivors' Psychological Distress & Symptom Management

NCT03743415
View directory record Official record
Conditions
Cancer
Interventions
Handbook, TIP-C plus Handbook
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
908 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 20, 2026, 1:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fulfillment Center Study on Work, Health, and Wellbeing

NCT05199415
View directory record Official record
Conditions
Psychological Distress, Psychological Well-being, Subjective Health, Injuries
Interventions
Health and Well-being Committee
Behavioral
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
3,459 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Oct 20, 2026, 1:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

NCT06279013
View directory record Official record
Conditions
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions
Counseling, Health Education, Interview, Medical Chart Review, Monitoring, Questionnaire Administration
Other · Behavioral
Lead sponsor
NRG Oncology
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2032
U.S. locations
30
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Albany, Georgia + 21 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Not listed Not applicable Interventional

Evaluating a New Program for Successfully Coping With Adversity

NCT05354492
View directory record Official record
Conditions
Trauma, Distress, Emotional, Psychological Distress
Interventions
Program to Support Well-Being after Adversity
Other
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2022 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional

Yoga for Psychological Distress in Gynecologic, Gastrointestinal, or Thoracic Cancer

NCT03385577
View directory record Official record
Conditions
Gynecologic Cancer, Adjustment, Gastrointestinal Cancer, Thoracic Cancer
Interventions
Stilling the Waters of Uncertainty: A yoga program for women with gynecologic, gastrointestinal (GI), or thoracic cancer
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Results available

Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration

NCT04785677
View directory record Official record
Conditions
Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Depressive Symptoms, Anxiety, Substance Use, Aggression, Coping Skills, Impulsive Behavior, Housing Problems, Recidivism, Stress, Occupational Stress, Psychological Distress
Interventions
Resiliency in Stressful Experiences (RISE) Program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Recruiting Not applicable Interventional

LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living With Metastatic Lung Cancer

NCT07177846
View directory record Official record
Conditions
Survivorship
Interventions
LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACT Group for Family Caregivers of Stroke Survivors

NCT07528261
View directory record Official record
Conditions
Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress, Caregiver Exhaustion, Caregiver Health Related QOL, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status, Caregiver Quality of Life, Caregiver Burden, Caregiver Mental Health, Caregiver Resilience and Stress, Caregiver Sense of Control Over Life, Caregiver Awareness, Caregiver Stress in Chronic Mental Illness
Interventions
Group-based ACT Intervention
Behavioral
Lead sponsor
The Wright Institute
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Recruiting Not applicable Interventional

Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

NCT06162741
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD), Depression, Anxiety
Interventions
Primary Care Brief Mindfulness Training (PCBMT), Moving Forward (MF)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Phoenix, Arizona • San Diego, California • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional

ACT Workshops: A Novel Delivery Modality to Increase Access to Care for Rural Veterans

NCT05196464
View directory record Official record
Conditions
Access to Care, Psychological Distress
Interventions
Acceptance and Commitment Therapy (ACT) Workshop, Treatment as usual (TAU)
Behavioral
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Oct 20, 2026, 1:23 AM EDT
Recruiting Not applicable Interventional

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

NCT07223736
View directory record Official record
Conditions
Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
Interventions
Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional

LOL: It's All Improv After Cancer!™

NCT03824132
View directory record Official record
Conditions
Breast Cancer, Psychological Distress
Interventions
Improvisational comedy classes, Waitlist control
Behavioral
Lead sponsor
Arash Asher, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional

Out of Pocket Cost Communication in Multiple Sclerosis Patients

NCT04257071
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Usual Care, OOP Cost Communication and Optimization
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 18, 2022 · Synced Oct 20, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Creating Access to Resources and Economic Support

NCT05971160
View directory record Official record
Conditions
Psychological Distress
Interventions
Financial education videos, Microgrant, Peer mentoring
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 20, 2026, 1:23 AM EDT