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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:28 AM EDT

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Showing 121–144 of 184 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Psychological Distress Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Feasibility Study of Remote Problem Management Plus for Adults Affected by COVID-19

NCT04617262
View directory record Official record
Conditions
Depression, Anxiety Disorders, Psychological Distress
Interventions
Remote Problem Management Plus
Behavioral
Lead sponsor
The New School
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy for Family Caregivers of People With Dementia

NCT04458870
View directory record Official record
Conditions
Psychological Distress
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Phase 1 Interventional

Education Program to Manage Emotional Stress of Stem Cell Transplant Recipients and Their Caregivers

NCT00423774
View directory record Official record
Conditions
Family Caregivers, Bone Marrow Transplantation
Interventions
Problem-Solving Education
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional Results available

Addressing Palliative Care Needs Among Intensive Care Unit Family Members

NCT03506438
View directory record Official record
Conditions
Critical Illness, Family Members, Psychological Distress, Informal Caregivers, Palliative Care
Interventions
Needs-focused mobile app, Usual care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Testing the Effectiveness of an Online Behavioral Intervention in Reducing Loneliness

NCT04112225
View directory record Official record
Conditions
Psychological Distress, Loneliness
Interventions
Happify
Behavioral
Lead sponsor
Happify Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
890 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Stress-Sensitive Problems Among Pregnant Black Women With Childhood Adversity

NCT05718479
View directory record Official record
Conditions
Maternal Psychological Distress, Perinatal Depression, Self-Regulation, Emotion
Interventions
Trauma Informed Prenatal Intervention (TPI), Prenatal Education Topics
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 20, 2026, 5:28 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Fertility Changes Due to Cancer: an Investigation of Meaning, Psychological Distress, and Psychologi

NCT05245162
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Mechanism of Change of Functional Analytic Psychotherapy

NCT03562962
View directory record Official record
Conditions
Interpersonal Functioning, Psychological Distress
Interventions
Functional Analytic Psychotherapy
Behavioral
Lead sponsor
University of Nevada, Reno
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 20, 2018 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings

NCT00974402
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2014 · Synced Oct 20, 2026, 5:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Psychological Distress and Outcomes in Hip Preservation Patients

NCT01550263
View directory record Official record
Conditions
Psychological Distress
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindful Moms: Mechanisms of Mindfulness-based Cognitive Therapy During Pregnancy and Postpartum

NCT05137925
View directory record Official record
Conditions
Psychological Distress, Pregnancy Related, Postpartum Blues, Postpartum Depression, Postpartum Anxiety, Postpartum Sadness
Interventions
Mindfulness-Based Cognitive Therapy (MBCT), Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Precision Psychiatry Continuity Clinic Project

NCT03260985
View directory record Official record
Conditions
Depressive Disorders, Depressive Symptoms, Anxiety Disorders and Symptoms, Psychological Distress, Mood Disorders
Interventions
Feedback Report
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Shift-and-persist and Cardiometabolic Markers Among Women in Puerto Rico

NCT06250738
View directory record Official record
Conditions
Psychological Distress, Cardiometabolic Syndrome
Interventions
Mindfulness-based Stress reduction program: Virtual, Home exercises
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Forms of Racial Discrimination Study

NCT03720600
View directory record Official record
Conditions
Psychological Distress
Interventions
MAB Intervention
Behavioral
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

ACT for Infertility: Case Series

NCT06388044
View directory record Official record
Conditions
Infertility, Psychological Distress, Acceptance and Commitment Therapy, Psychological Flexibility
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Personalized Feedback for Distress Intolerant Smokers

NCT03918031
View directory record Official record
Conditions
Anxiety Disorders, Depression, Psychological Distress, Tobacco Dependence, Smoking, Tobacco, Smoking, Cigarette
Interventions
PFI for Smoking & Distress Tolerance, PFI for Smoking Only
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Pain Coping Skills for Colorectal Cancer Survivors

NCT02706301
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Telephone-Based Coping Skills Training (CST)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Oct 20, 2026, 5:28 AM EDT
Recruiting Not applicable Interventional

Stress Management and Meditative Movements for Asian Americans With Depression and Physical Symptoms

NCT07610928
View directory record Official record
Conditions
Depression / Major Depressive Disorder, Mental Health (Depression)
Interventions
Stress Management and Resiliency Training with Qigong/Tai Chi, Healthy Living Program
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 20, 2026, 5:28 AM EDT
Withdrawn No phase listed Observational

A Prospective Study of Body Image, Social Avoidance and Distress and Psychological Functioning in Burn Patients

NCT01136070
View directory record Official record
Conditions
Depression, Anxiety, Body Image
Interventions
Not listed
Lead sponsor
Saint Elizabeth Regional Medical Center
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Mindfulness Training and Respiration Biosignal Feedback - Study 1

NCT06625697
View directory record Official record
Conditions
Psychological Distress, Develop a Respiration Biosignal Feedback Algorithm, Utilize Respiration Algorithm to Predict Mindfulness Skills
Interventions
Mindfulness Meditation
Behavioral
Lead sponsor
Equa Health
Industry
Eligibility
18 Years to 30 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 20, 2026, 5:28 AM EDT
Recruiting Not applicable Interventional

Women's Wellbeing Study

NCT07195019
View directory record Official record
Conditions
Distress, Psychological
Interventions
Integrative Yoga & Mindful Self-Compassion training, Women's Wellbeing Education
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 20, 2026, 5:28 AM EDT
Recruiting Not applicable Interventional

Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents

NCT07626944
View directory record Official record
Conditions
BPSD, Caregiver Distress, Well-being, Mood
Interventions
Personalized Music Listening (PML), Binaural Beat Music (BBM), Spatialized Music (SM)
Other
Lead sponsor
Maharishi International University
Other
Eligibility
55 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Denver, Colorado • Lakewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 20, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Development and Feasibility Testing of a Suicide Prevention Intervention for Sexual and Gender Minority Youth

NCT05724784
View directory record Official record
Conditions
Psychological Distress, Suicidal Ideation
Interventions
Flourish
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 17 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 20, 2026, 5:28 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The MObile AssessMENT of Behavioral and Psychological Symptoms of Dementia in Amnestic MCI and AD (MOMENT) Study

NCT04482036
View directory record Official record
Conditions
Alzheimer Disease, Mild Memory Disturbance, Mild Cognitive Impairment
Interventions
Mobile Phone Application Assessments, Standard Assessments
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 120 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 20, 2026, 5:28 AM EDT