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ClinicalTrials.gov public records Last synced Sep 17, 2026, 5:15 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Quadraplegia Clear all
Completed Phase 2Phase 3 Interventional Results available

Fenofibrate Treatment in SCI

NCT02455336
View directory record Official record
Conditions
Spinal Cord Injury, Dyslipidemia
Interventions
Fenofibrate, No intervention
Drug · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 69 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

NCT05095454
View directory record Official record
Conditions
Paraplegia, Tetraplegia, Paralysis, Quadraplegia
Interventions
Percutaneous epidural electrical spinal stimulation, Transcutaneous electrical spinal stimulation
Device
Lead sponsor
Kristin Zhao, PhD
Other
Eligibility
22 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia

NCT06087445
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
NeuroLife EMG-FES Sleeve System
Device
Lead sponsor
Ohio State University
Other
Eligibility
22 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation

NCT01539109
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Rehabilitation, Noninvasive brain stimulation: tDCS, Sham tDCS: placebo noninvasive brain stimulation
Behavioral · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia

NCT00904436
View directory record Official record
Conditions
Dyspnea, Tetraplegia
Interventions
ipratropium (Atrovent)
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2009 · Synced Sep 17, 2026, 5:15 AM EDT
Not yet recruiting Phase 3 Interventional

A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury

NCT07799532
View directory record Official record
Conditions
Chronic Spinal Cord Injury
Interventions
NVG-291, Placebo
Drug
Lead sponsor
NervGen Pharma
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
17
States / cities
Birmingham, Alabama • Downey, California • Englewood, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting No phase listed Observational

Nerve Transfer to Improve Function in High Level Tetraplegia

NCT06288763
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
Stanford, California • Miami, Florida • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

NCT06511934
View directory record Official record
Conditions
Brainstem Stroke, ALS, Tetraplegia, Spinal Cord Injuries, Cervical Spinal Cord Injury
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Terminated Not applicable Interventional

Improving Hand Recovery With Neuromodulation in Tetraplegia

NCT03954496
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia, Unspecified, Incomplete, Chronic
Interventions
transcranial direct current stimulation, Intensive upper extremity motor training
Device · Behavioral
Lead sponsor
Sara Shahid Salles
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 23, 2021 · Synced Sep 17, 2026, 5:15 AM EDT
Terminated Phase 4 Interventional Results available

Albuterol to Improve Respiratory Strength in SCI

NCT02508311
View directory record Official record
Conditions
Spinal Cord Injury, Respiratory Muscle Weakness
Interventions
Oral Albuterol Extended Release, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

High Definition Neuromuscular Stimulation in Tetraplegia

NCT04075812
View directory record Official record
Conditions
Spinal Cord Injury at C4-C6 Level
Interventions
Neuromuscular Stimulator
Device
Lead sponsor
Ohio State University
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 8, 2021 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Phase 1Phase 2 Interventional

Psilocybin to Treat Depression in Spinal Cord Injury

NCT07251491
View directory record Official record
Conditions
Spinal Cord Injury, Depression - Major Depressive Disorder, Veteran
Interventions
Psilocybin (Usona Institute)
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Not yet recruiting Not applicable Interventional

Feasibility of Home Based Transcutaneous Spinal Cord Stimulation for Persons With SCI

NCT06140706
View directory record Official record
Conditions
Tetraplegia
Interventions
transcutaneous Spinal Cord Stimulation (tSCS)
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

A Neuroprosthesis for Seated Posture and Balance

NCT01474148
View directory record Official record
Conditions
Spinal Cord Injury, Paralysis, Tetraplegia, Paraplegia
Interventions
IRS-8 (8-Channel implanted stimulator-telemeter)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

NCT07225582
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Interventions
Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Enrolling by invitation Not applicable Interventional

NIBS Therapy in Subacute Spinal Cord Injury

NCT06247904
View directory record Official record
Conditions
Traumatic Spinal Cord Injury, Tetraplegia/Tetraparesis
Interventions
Active rTMS, sham rTMS
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Not listed Phase 3 Interventional

Combined Robotic Training and tDCS in Chronic SCI

NCT03555838
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia
Interventions
transcranial direct current stimulation, sham transcranial direct current stimulation
Other
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

At-Home Genital Nerve Stimulation for SCI Bowel

NCT06836739
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Genital nerve stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Dose Escalation Study of AST-OPC1 in Spinal Cord Injury

NCT02302157
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Spine Injury, Spinal Cord Trauma
Interventions
AST-OPC1
Biological
Lead sponsor
Lineage Cell Therapeutics, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
9
States / cities
La Jolla, California • Los Angeles, California • San Jose, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Sep 17, 2026, 5:15 AM EDT
Suspended Phase 2 Interventional

Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries

NCT00073853
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Autologous Incubated Macrophages (cell therapy)
Procedure
Lead sponsor
Proneuron Biotechnologies
Industry
Eligibility
16 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
6
States / cities
Englewood, Colorado • Atlanta, Georgia • Newark, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2009 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Restoring Arm and Hand Function With Non-invasive Spinal Stimulation

NCT01906424
View directory record Official record
Conditions
Paralysis, Spinal Cord Injury
Interventions
Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
NeuroEnabling Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Los Angeles, California • San Juan Capistrano, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 17, 2026, 5:15 AM EDT
Not listed Phase 2 Interventional

Surgical Management of Spinal Cord Injuries In Neck

NCT00475748
View directory record Official record
Conditions
Central Cord Syndrome, Spinal Cord Injury, Quadriparesis
Interventions
Early and late surgery for traumatic central cord syndrome
Procedure
Lead sponsor
Maryland Department of Health and Mental Hygiene
Government
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2009 · Synced Sep 17, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury

NCT02235714
View directory record Official record
Conditions
Tetraplegia, Asthma
Interventions
Not listed
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2014 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

An Early Feasibility Study of the ReHAB System

NCT03898804
View directory record Official record
Conditions
Tetraplegia
Interventions
BCI and FES
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
22 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 17, 2026, 5:15 AM EDT