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Showing 1–24 of 258 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Radical Prostatectomies Clear all
Withdrawn Phase 2Phase 3 Interventional

Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy

NCT04939987
View directory record Official record
Conditions
Radical Prostatectomies
Interventions
Tramadol, Gabapentin, Hydrocodone-Acetaminophen, Oxycodone-Acetaminophen, Ketorolac, Acetaminophen, Ketorolac tromethamine, Ketamine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 75 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2022 · Synced Jul 24, 2026, 2:42 PM EDT
Active, not recruiting Phase 3 Interventional

Trial of Modifications to Radical Prostatectomy

NCT01407263
View directory record Official record
Conditions
Prostate Cancer
Interventions
Lymph node template, Transverse versus vertical closure, antibiotic prophylaxis, Hemostatic Agent
Procedure · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Male only
Enrollment
3,204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
5
States / cities
Basking Ridge, New Jersey • Montvale, New Jersey • Harrison, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Phase 3 Interventional Results available

PROvenge Treatment and Early Cancer Treatment

NCT00779402
View directory record Official record
Conditions
Prostate Cancer
Interventions
Control, Sipuleucel-T
Other · Biological
Lead sponsor
Dendreon
Industry
Eligibility
18 Years to 80 Years · Male only
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2015
U.S. locations
18
States / cities
Berkeley, California • Laguna Hills, California • Aurora, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2018 · Synced Jul 24, 2026, 2:42 PM EDT
Terminated Not applicable Interventional

A Prospective Trial on Nerve Sparing Techniques Performed in Radical Prostatectomy

NCT04393831
View directory record Official record
Conditions
Prostate Cancer, Quality of Life
Interventions
Retzius sparing
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jul 24, 2026, 2:42 PM EDT
Recruiting Phase 2 Interventional

FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer

NCT06636682
View directory record Official record
Conditions
Prostate Cancer (Adenocarcinoma), Prostate CA, Prostate Cancers, Prostate Cancer (Post Prostatectomy), Prostate Cancer, Prostate Cancer Patients Undergoing Radical Prostatectomy, High-risk Prostate Cancer
Interventions
FK-PC101, Standard of Care (SOC)
Biological
Lead sponsor
Cellvax Therapeutics Inc
Industry
Eligibility
Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Chicago, Illinois • Gahanna, Ohio • Myrtle Beach, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 20, 2024 · Synced Jul 24, 2026, 2:42 PM EDT
Completed No phase listed Observational

Men Undergoing Radical Prostatectomy

NCT00582530
View directory record Official record
Conditions
Prostate Cancer
Interventions
Whole Blood Draw
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
513 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Magnetic Resonance Imaging-Transrectal Ultrasound Fusion Image-Guided Prostate Biopsy Following Radical Prostatectomy in Patients With Prostate Cancer

NCT01764347
View directory record Official record
Conditions
Prostate Cancer
Interventions
therapeutic conventional surgery, ultrasound-guided prostate biopsy, magnetic resonance imaging
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
Male only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2014 · Synced Jul 24, 2026, 2:42 PM EDT
Withdrawn No phase listed Observational

Quality of Life in Men With High Risk Localized Prostate Cancer

NCT00877617
View directory record Official record
Conditions
Prostate Cancer
Interventions
QOL Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2012 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Ultrasound Imaging in Finding Prostate Cancer in Patients Undergoing Surgery

NCT02024178
View directory record Official record
Conditions
Prostate Cancer
Interventions
Ultrasound Imaging
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Male only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Not applicable Interventional Results available

Use of Hypothermia During Robotic Prostatectomy

NCT00915031
View directory record Official record
Conditions
Prostate Cancer
Interventions
UroCool
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Male only
Enrollment
738 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Phase 2 Interventional Results available

Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer

NCT00589472
View directory record Official record
Conditions
Prostate Adenocarcinoma, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer, Stage III Prostate Cancer
Interventions
Bicalutamide, Goserelin Acetate, Laboratory Biomarker Analysis, Leuprolide Acetate, Therapeutic Conventional Surgery, Vorinostat
Drug · Other · Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
19 Years and older · Male only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
15
States / cities
Los Angeles, California • San Francisco, California • Chicago, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 24, 2026, 2:42 PM EDT
Terminated Phase 2 Interventional Results available

High Resolution, 18F-PSMA PET-MRI Before Prostate Cancer HIFU or Radical Prostatectomy

NCT04461509
View directory record Official record
Conditions
Prostatic Neoplasms, Genital Neoplasms, Male, Urogenital Neoplasms, Neoplasms by Site, Neoplasms, Genital Diseases, Male, Prostatic Disease
Interventions
18F-PSMA
Drug
Lead sponsor
Alessandro D'Agnolo
Other
Eligibility
18 Years and older · Male only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Phase 2 Interventional

Hormone Therapy in Treating Patients With Prostate Cancer

NCT00003323
View directory record Official record
Conditions
Prostate Cancer, Sexual Dysfunction and Infertility
Interventions
finasteride, flutamide, quality-of-life assessment
Drug · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
Male only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2010
U.S. locations
43
States / cities
Birmingham, Alabama • La Jolla, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2016 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Not applicable Interventional Results available

MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction

NCT05673005
View directory record Official record
Conditions
Erectile Dysfunction Following Radical Prostatectomy
Interventions
MED3000 topical gel
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Phase 2 Interventional Results available

Treatment of Prostate Cancer With Adjuvant Bevacizumab Plus Erlotinib

NCT00203424
View directory record Official record
Conditions
Prostate Cancer
Interventions
Erlotinib + Bevacizumab
Drug
Lead sponsor
Translational Oncology Research International
Other
Eligibility
18 Years and older · Male only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
16
States / cities
Alhambra, California • Bakersfield, California • Fullerton, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Phase 1 Interventional

A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.

NCT05938270
View directory record Official record
Conditions
Prostate Cancer
Interventions
Saruparib (AZD5305), Darolutamide, No Treatment
Drug · Other
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older · Male only
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Detroit, Michigan • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Diagnosing the Extent of Disease in Patients With Prostate Cancer

NCT00032058
View directory record Official record
Conditions
Prostate Cancer
Interventions
magnetic resonance imaging, magnetic resonance spectroscopic imaging
Procedure
Lead sponsor
American College of Radiology Imaging Network
Network
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
8
States / cities
San Francisco, California • New Haven, Connecticut • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2011 · Synced Jul 24, 2026, 2:42 PM EDT
Terminated No phase listed Observational

Determination of the Diagnostic Detection Rate of Axumin (Fluciclovine) Digital PET/CT, Post-prostatectomy

NCT04234399
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
Fluciclovine PET/CT using a digital PET/CT
Diagnostic Test
Lead sponsor
University of Vermont
Other
Eligibility
40 Years and older · Male only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jul 24, 2026, 2:42 PM EDT
Withdrawn Not applicable Interventional

Single-Port Versus Multi-Port Robotic Radical Prostatectomy

NCT04696263
View directory record Official record
Conditions
Malignant Neoplasm of Prostate
Interventions
Da Vinci ® Xi system - MP Robotic Radical Prostatectomy, Da Vinci ® SP system - SP Robotic Radical Prostatectomy
Device
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Phase 1 Interventional

Diffuse Optical Imaging With Indocyanine Green Solution in Imaging Pelvic Lymph Nodes in Patients With Stage II Prostate Cancer Undergoing Surgery

NCT02119858
View directory record Official record
Conditions
Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
Interventions
indocyanine green solution, diffuse optical imaging, robot-assisted laparoscopic surgery, therapeutic lymphadenectomy
Drug · Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Phase 2 Interventional Results available

Samarium Sm 153 Lexidronam Pentasodium and 3-Dimensional Conformal Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Rising Prostate-Specific Antigen Levels After Radical Prostatectomy for Prostate Cancer

NCT00551525
View directory record Official record
Conditions
Prostate Cancer
Interventions
Radiotherapy, Samarium 153
Radiation · Drug
Lead sponsor
Radiation Therapy Oncology Group
Network
Eligibility
18 Years to 120 Years · Male only
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
29
States / cities
Phoenix, Arizona • Auburn, California • Cameron Park, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Modifications to Radical Prostatectomy: Feasibility Study

NCT00928850
View directory record Official record
Conditions
Prostate Cancer
Interventions
radical prostatectomy with urethral irrigation but no fascial suturing, QOL forms, radical prostatectomy with fascial suturing but no urethral irrigation, QOL forms, radical prostatectomy with both urethral irrigation and fascial suturing, QOL forms, radical prostatectomy with neither urethral irrigation nor fascial suturing, QOL forms
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Male only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Jul 24, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music Listening as a Postanesthesia Care Unit (PACU) Nursing Intervention

NCT04596917
View directory record Official record
Conditions
Prostate Cancer
Interventions
Preferred music listening, Relaxation breathing narrative over hypnotic music listening
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
45 Years to 80 Years · Male only
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Jul 24, 2026, 2:42 PM EDT
Terminated Early Phase 1 Interventional Results available

Testosterone for Penile Rehabilitation After Radical Prostatectomy

NCT00848497
View directory record Official record
Conditions
Hypogonadism, Erectile Dysfunction
Interventions
Testim®, Placebo Testim®, Viagra®
Drug · Other
Lead sponsor
Mohit Khera
Other
Eligibility
18 Years and older · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2015 · Synced Jul 24, 2026, 2:42 PM EDT