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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Radicular Pain Clear all
Completed Phase 4 Interventional Results available

Effectiveness of Cervical Transforaminal Epidural Steroid Injection

NCT04544683
View directory record Official record
Conditions
Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
Interventions
Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Sep 11, 2026, 4:21 PM EDT
Completed No phase listed Observational

Non-organic Signs to Predict Outcomes for Neck Pain

NCT04320836
View directory record Official record
Conditions
Cervical Radiculopathy, Cervical Radicular Pain
Interventions
Cervical epidural steroid injection
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
78 participants
Timeline
2020 – 2022
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Sep 11, 2026, 4:21 PM EDT
Withdrawn Phase 4 Interventional

Eplerenone as a Supplement to Epidural Steroid Injections

NCT03418649
View directory record Official record
Conditions
Degenerative Intervertebral Discs, Sciatic Radiculopathy, Low Back Pain
Interventions
Eplerenone 50 Mg Tab, Placebo Oral Tablet
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Cincinnati, Ohio • West Chester, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Not applicable Interventional Results available

Implementation of Pedometer for Monitoring Step Count Pre and Post Lumbar ESI for Radicular Pain

NCT02356783
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Pedometer
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Not applicable Interventional

Chronic Lumbosacral Radiculopathy: Impact of an Analgesic Dietary Intervention on Pain & Function

NCT02531711
View directory record Official record
Conditions
Pain
Interventions
Diet A, Diet B
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 4 Interventional Results available

Orphenadrine and Methocarbamol for LBP

NCT02665286
View directory record Official record
Conditions
Low Back Pain
Interventions
Orphenadrine, Methocarbamol, Naproxen, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 69 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 3 Interventional Results available

Corticosteroid Lumbar Epidural Analgesia for Radiculopathy

NCT03372161
View directory record Official record
Conditions
Lumbosacral Radicular Pain
Interventions
SP-102, Placebo
Drug
Lead sponsor
Scilex Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
37
States / cities
Mobile, Alabama • Phoenix, Arizona • Tempe, Arizona + 30 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Sep 11, 2026, 4:21 PM EDT
Recruiting Not applicable Interventional

Discogen for Low Back Pain

NCT06611397
View directory record Official record
Conditions
Disc Herniation
Interventions
Discogen Low pulsed ultrasound treatment, Discogen Sham Treatment
Device
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 4 Interventional Results available

True Functional Restoration and Analgesia in Non-Radicular Low Back Pain

NCT01455519
View directory record Official record
Conditions
Low Back Pain
Interventions
Hydromorphone ER, Sugar pill
Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 23, 2017 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Not applicable Interventional Results available

Effect of Acupuncture and Pain Medication on Radicular Pain Using QST

NCT01678586
View directory record Official record
Conditions
Pain
Interventions
Acupuncture, Sham Acupuncture, Gabapentin, Sham Gabapentin
Other · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Diazepam Use With Standard Management for Acute Low Back Pain

NCT02646124
View directory record Official record
Conditions
Low Back Pain
Interventions
Naproxen, Placebo, Diazepam
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
21 Years to 69 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2018 · Synced Sep 11, 2026, 4:21 PM EDT
Terminated Not applicable Interventional Results available

Evaluation of the Percutaneous SCS Trial Using the DSSEP Collision Testing

NCT02614079
View directory record Official record
Conditions
Back Pain With Radiation
Interventions
DSSEP
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Sep 11, 2026, 4:21 PM EDT
Withdrawn Phase 4 Interventional

Adjunctive 5% Lidocaine Patches for Acute Non-radicular Low Back Pain in Emergency Department Patients

NCT03301766
View directory record Official record
Conditions
Low Back Pain
Interventions
lidocaine 5% patch, standard therapy, Non-medicated patch
Drug
Lead sponsor
Cook County Health
Government
Eligibility
24 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Sep 11, 2026, 4:21 PM EDT
Completed No phase listed Observational

Comparison of Gabapentin and Pregabalin for Radicular Pain

NCT02064790
View directory record Official record
Conditions
Radicular; Neuropathic, Lumbar, Lumbosacral, Radicular; Neuropathic, Cervical
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 2 Interventional

Naltrexone and Clonidine Combination (ATNC05) in the Treatment of Chronic Back Pain

NCT01415895
View directory record Official record
Conditions
Back Pain, Lower Back Pain, Cervical Pain
Interventions
Naltrexone and Clonidine Combination, placebo
Drug
Lead sponsor
Annette C. Toledano MD
Industry
Eligibility
19 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
North Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 4 Interventional Results available

Comparative Trial Via Tranforaminal Approach Versus Epidural Catheter Via Interlaminar Approach

NCT03382821
View directory record Official record
Conditions
Cervical Radiculopathy
Interventions
Transforaminal ESI with dexamethasone, Transforaminal catheter-targeted ESI with triamcinolone, Dexamethasone Sodium Phosphate 10 MG/ML, Lidocaine, Triamcinolone Acetonide 40mg/mL
Procedure · Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Not applicable Interventional

MR Guided Focused Ultrasound for Treatment of Neuropathic Pain

NCT03111277
View directory record Official record
Conditions
Severe Neuropathic Pain Due to Radiculopathy or Radicular Injury, Spinal Cord Injuries, Phantom Limb Pain
Interventions
Experimental: ExAblate Transcranial treatment
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 2 Interventional Results available

A Research Study to Characterize the Pharmacodynamics and Safety of Repeat Dose SP-102

NCT03613662
View directory record Official record
Conditions
Lumbosacral Radicular Pain
Interventions
SP-102
Drug
Lead sponsor
Semnur Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Sep 11, 2026, 4:21 PM EDT
Withdrawn Phase 4 Interventional

Pharmacokinetic Profile and Dermatomal Coverage of the Erector Spinae Plane Block

NCT03874806
View directory record Official record
Conditions
Pain, Postoperative, Pain, Chest
Interventions
Ropivacaine 0.25%-NaCl 0.9% Injectable Solution, Ropivacaine 0.2%-NaCl 0.9% Injectable Solution
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Sep 11, 2026, 4:21 PM EDT
Completed No phase listed Observational

Effectiveness Study of Physical Therapy as an Adjunct to a Lumbar Therapeutic Selective Nerve Root Block

NCT00934284
View directory record Official record
Conditions
Sciatic Neuropathy, Radiculopathy, Intervertebral Disk Displacement
Interventions
Lumbar injection, Rehabilitation following lumbar injection
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 11, 2026, 4:21 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

NCT05721027
View directory record Official record
Conditions
Radiculopathy, Lumbosacral Region, Back Pain With Radiation, Low Back Pain
Interventions
Ibuprofen 400 mg, Dexamethasone Oral, Educational Intervention
Drug · Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 4 Interventional

Topical Lidocaine Patch in Low Back Pain

NCT00904540
View directory record Official record
Conditions
Acute and Chronic Non-radicular LBP
Interventions
Lidoderm®
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
7
States / cities
Phoenix, Arizona • Mill Valley, California • Weston, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2024 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 4 Interventional Results available

C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain

NCT02095197
View directory record Official record
Conditions
Radicular; Neuropathic, Cervical, Neck Pain
Interventions
Triamcinolone 80mg
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 75 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Sep 11, 2026, 4:21 PM EDT
Completed Phase 4 Interventional Results available

Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain

NCT02226159
View directory record Official record
Conditions
Pain, Radiating
Interventions
Lidocaine, Lidocaine with Dexamethasone
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 11, 2026, 4:21 PM EDT