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Showing 1–24 of 731 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Reconstructive Surgery Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer

NCT06090630
View directory record Official record
Conditions
Benign Breast Neoplasm, Breast Carcinoma, Malignant Breast Neoplasm
Interventions
Diffusion Weighted Imaging, Magnetic Resonance Spectroscopic Imaging
Procedure
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery

NCT03052816
View directory record Official record
Conditions
Pain, Postoperative, Pelvic Organ Prolapse
Interventions
Ice T, Motrin/Percocet/Dilaudid for breakthrough
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study

NCT03481725
View directory record Official record
Conditions
Rotator Cuff Repair, Anterior Cruciate Ligament Reconstruction, Ankle Arthrodesis or Arthroplasty, Hallux Valgus Correction
Interventions
ACTIVE peripheral nerve stimulation with a percutaneously inserted lead and wearable stimulator (SPR Therapeutics, Cleveland, Ohio), SHAM peripheral nerve stimulation with a percutaneously inserted lead and wearable SHAM stimulator (SPR Therapeutics, Cleveland, Ohio)
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
6
States / cities
San Diego, California • Bethesda, Maryland • Fort Bragg, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Jul 21, 2026, 6:09 PM EDT
Active, not recruiting Phase 3 Interventional

Non-Narcotic Pain Control After ACL Reconstruction

NCT06973785
View directory record Official record
Conditions
ACL - Anterior Cruciate Ligament Rupture, ACL Injuries
Interventions
dispense of study drug, Ketorolac
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
15 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Coral Springs, Florida • Garfield, Ohio • Strongsville, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Vibratory Stimuli, A Novel Rehabilitation Method for Preventing Post - Traumatic Knee Osteoarthritis

NCT02605876
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Whole body vibration, Local muscle vibration
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Comparison of 3 Techniques for Recreation of Anterior Cruciate Ligament Anatomic Footprint

NCT02795247
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Anterior Cruciate Ligament Reconstruction
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction

NCT01969448
View directory record Official record
Conditions
Ductal Carcinoma in Situ - Category, Breast Cancer, Prophylactic Mastectomy
Interventions
Inframammary Fold Incision or Lateral Radial Incision, Lateral Radial Incision, Inframammary Fold Incision, Laser-assisted fluorescence angiography, Indocyanine Green
Procedure · Device · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Post-Operative Outcomes of Low Thermal Dissection vs. Traditional Electrosurgery

NCT03711916
View directory record Official record
Conditions
Breast Cancer, Mastectomy, Perfusion; Complications, Hemostasis
Interventions
PlasmaBlade 3.0S
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2019 · Synced Jul 21, 2026, 6:09 PM EDT
Not listed Not applicable Interventional

DuraSorb® in Prosthetic Breast Reconstruction

NCT04646057
View directory record Official record
Conditions
Breast Reconstruction
Interventions
DuraSorb®
Device
Lead sponsor
Surgical Innovation Associates, Inc.
Industry
Eligibility
22 Years to 70 Years · Female only
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
7
States / cities
Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Terminated Not applicable Interventional

Hand Transplantation for the Reconstruction of Below the Elbow Amputations

NCT00778856
View directory record Official record
Conditions
Amputation, Transplantation
Interventions
Hand transplantation
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Rapid Stress/Rest Single-Day Tc-99m Sestamibi Myocardial Single Photon Emission Computed Tomography

NCT01434641
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
low-dose stress MPI SPECT
Other
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2016 · Synced Jul 21, 2026, 6:09 PM EDT
Terminated Phase 3 Interventional Results available

A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm

NCT03383666
View directory record Official record
Conditions
Unruptured Wide-neck Intracranial Aneurysms
Interventions
PulseRider® Aneurysm Neck Reconstruction Device
Device
Lead sponsor
Pulsar Vascular
Industry
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Kansas City, Kansas • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Phase 2 Interventional

Delayed-Immediate Breast Reconstruction

NCT00473122
View directory record Official record
Conditions
Breast Cancer
Interventions
Delayed-Immediate Breast Reconstruction
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2016 · Synced Jul 21, 2026, 6:09 PM EDT
Withdrawn Not applicable Interventional

Prepectoral vs Partial Subpectoral Two-Stage Implant-Based Breast Reconstruction

NCT04874402
View directory record Official record
Conditions
Breast Reconstruction Following Mastectomy
Interventions
Prepectoral approach, Partial Subpectoral approach
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Jul 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional

Dissemination of BREASTChoice AIM1-B

NCT07396766
View directory record Official record
Conditions
Breast Cancer, Breast Neoplasms
Interventions
Baseline Questionnaire, Semi structured Interview, Post Survey
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional

BFRT MPFL and ACL Reconstruction Rehab

NCT05426954
View directory record Official record
Conditions
Medial Patellar Femoral Ligament Reconstruction Rehabilitation, Anterior Cruciate Ligament Reconstruction Rehabilitation
Interventions
Rehabilitation utilizing blood flow restrictive therapy
Other
Lead sponsor
Richard Watson, PT
Other
Eligibility
13 Years to 40 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Active, not recruiting Not applicable Interventional Results available

Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma

NCT03422003
View directory record Official record
Conditions
Breast Cancer
Interventions
Radiation Therapy
Radiation
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
15
States / cities
San Francisco, California • Stanford, California • Edwards, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Terminated Not applicable Interventional

Reduced Radiation Dose and IR-impact on Coronary Calcium Quantification

NCT04267094
View directory record Official record
Conditions
Atherosclerotic Plaque
Interventions
Iterative reconstruction at reduced radiation dose
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction

NCT04091672
View directory record Official record
Conditions
Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin, Surgical Wound, Skin Cancer, Cellulitis, Infection, Necrotizing Fasciitis, Gun Shot Wound
Interventions
Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
Procedure · Device
Lead sponsor
Avita Medical
Industry
Eligibility
5 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
18
States / cities
Phoenix, Arizona • Tucson, Arizona • Orange, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Terminated Not applicable Interventional Results available

Liposomal Bupivacaine in Implant Based Breast Reconstruction

NCT02659501
View directory record Official record
Conditions
Breast Cancer, Postoperative Pain
Interventions
Liposomal bupivacaine, Bupivacaine with epinephrine, Morphine sulfate, Hydrocodone/acetaminophen, Diazepam
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Jul 21, 2026, 6:09 PM EDT
Terminated No phase listed Observational

Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI

NCT00820456
View directory record Official record
Conditions
Colorectal Neoplasm, Hepatic Neoplasm
Interventions
DCE-MRI
Other
Lead sponsor
American College of Radiology
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
5
States / cities
Hershey, Pennsylvania • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 21, 2026, 6:09 PM EDT
Not yet recruiting Phase 4 Interventional

Mochida ReFeel for Digital Nerve Injuries

NCT07524465
View directory record Official record
Conditions
Digital Nerve Injury, Nerve Reconstruction
Interventions
ReFeel
Device
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years to 69 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nipple Sparing Mastectomy - Cosmetic Outcomes

NCT01002014
View directory record Official record
Conditions
Breast Cancer, Breast Reconstruction, Cosmesis
Interventions
Nipple Sparing Mastectomy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2018
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Jul 21, 2026, 6:09 PM EDT
Not yet recruiting Phase 1 Interventional

Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.

NCT07004764
View directory record Official record
Conditions
Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Calcaneus Fractures, Talus Fracture, Wound Infection Deep, Wound Infection Post-Traumatic, Wound Dehiscence, Surgical
Interventions
Nitroglycerin Ointment 2%
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 21, 2026, 6:09 PM EDT