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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Recurrent UTIs Clear all
Completed Phase 4 Interventional Results available

Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women

NCT01958073
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
Conjugated Estrogen Vaginal Cream, Estradiol Ring, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
La Jolla, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 20, 2020 · Synced Sep 3, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Effect of Chlorhexidine Gluconate Bladder Instillations in Patients With Chronic Suprapubic Catheters on Unplanned Healthcare Encounters and Quality of Life

NCT06163469
View directory record Official record
Conditions
Neurogenic Bladder, Urinary Retention
Interventions
Bladder instillation with Irrisept
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 3, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections

NCT06940622
View directory record Official record
Conditions
Recurrent UTIs, Recurrent Urinary Tract Infections, Recurrent Urinary Tract Infections in Women, Recurrent Urinary Tract Infection, Cystitis Recurrent, Cystitis Chronic, UTI, UTI - Urinary Tract Infection, UTI - Lower Urinary Tract Infection
Interventions
D-Mannose, Placebo
Dietary Supplement
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
55 Years to 85 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 3, 2026, 6:57 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Nutraceutical Efficacy for rUTI

NCT03395288
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
D-Mannose
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years and older · Female only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 3, 2026, 6:57 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo

NCT04807894
View directory record Official record
Conditions
Recurrent Urinary Tract Infection, Vaginal Atrophy, Postmenopausal Disorder
Interventions
Vaginal Cream with Applicator
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
60 Years to 90 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Phase 2 Interventional

Cranberry Juice for the Prevention of Recurrent Urinary Tract Infections

NCT00128128
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Cranberry juice cocktail
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 45 Years · Female only
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
New Haven, Connecticut • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Sep 3, 2026, 6:57 AM EDT
Completed No phase listed Observational

Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections

NCT04495699
View directory record Official record
Conditions
Urinary Tract Infections, Kidney Stone
Interventions
None - observational
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Phoenix, Arizona • San Diego, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 3, 2026, 6:57 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Recurrent Urinary Tract Infections and the Microbiome

NCT04831840
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Fort Lauderdale, Florida • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Fecal Microbiota Transplantation (FMT) for MDRO UTI

NCT03367910
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Fecal microbiota transplant
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Sep 3, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

An Efficacy Study of a Dietary Supplement Drink Mix for Urinary Health Improvement

NCT07453693
View directory record Official record
Conditions
UTI's
Interventions
FLUSH
Dietary Supplement
Lead sponsor
Bonafide Health
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Harrison, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Cranberry Beverage on Women With Recent History of Urinary Tract Infections

NCT01776021
View directory record Official record
Conditions
Urinary Tract Infections, Infection, Urologic Diseases
Interventions
cranberry juice, placebo beverage
Other
Lead sponsor
Ocean Spray Cranberries, Inc.
Industry
Eligibility
20 Years to 70 Years · Female only
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
17
States / cities
Chandler, Arizona • Scottsdale, Arizona • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2015 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Probiotics and Multi-Drug Resistant Urinary Tract Infection

NCT03644966
View directory record Official record
Conditions
Urinary Tract Infections, Recurrent UTI, Antibiotic Resistant Infection
Interventions
Bifidobacterium infantis, Placebo, Antibiotics
Dietary Supplement · Other · Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Jefferson, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 3, 2026, 6:57 AM EDT
Terminated Early Phase 1 Interventional

Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder

NCT03143920
View directory record Official record
Conditions
Chronic Interstitial Cystitis, Painful Bladder Syndrome, Recurrent Urinary Tract Infection
Interventions
Hyperbaric Oxygen Therapy-
Combination Product
Lead sponsor
University of California, San Diego
Other
Eligibility
35 Years to 70 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2022 · Synced Sep 3, 2026, 6:57 AM EDT
Completed No phase listed Observational

Diagnosis, Antibiotic Prescribing Practices and Outcomes of cUTI in an Outpatient Setting

NCT05091931
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Not listed
Lead sponsor
Pathnostics
Industry
Eligibility
18 Years and older
Enrollment
3,308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Louisville, Kentucky • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Phase 2 Interventional

Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections

NCT05472779
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
Periurethral application of estradiol cream, Intravaginal application of estradiol cream
Drug
Lead sponsor
Stephanie Wang Zuo
Other
Eligibility
18 Years and older · Female only
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Cranberry Township, Pennsylvania • Erie, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

EHR-integrated rUTI Texting Platform

NCT06035601
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
EHR-integrated texting platform (Urotrust), Usual care
Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Vaccine for Recurrent Urinary Tract Infections in Women

NCT00261248
View directory record Official record
Conditions
Recurrent Urinary Tract Infections in Women
Interventions
Immunization with inactivated bacteria
Biological
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2003
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 4, 2015 · Synced Sep 3, 2026, 6:57 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections

NCT06353269
View directory record Official record
Conditions
Recurrent Urinary Tract Infection, Hypoestrogenism
Interventions
Estring Vaginal Product, Vagifem, Estrace 0.01% Vaginal Cream
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection

NCT04301934
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Mona Lisa Touch, Conjugated estrogen, Estradiol
Device · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 3, 2026, 6:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIs

NCT03077711
View directory record Official record
Conditions
Urinary Tract Infections, Recurrent
Interventions
Trimethoprim, Methenamine hippurate
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Sep 3, 2026, 6:57 AM EDT
Recruiting Phase 1 Interventional

Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections

NCT06907199
View directory record Official record
Conditions
Recurrent UTIs, Cystitis Recurrent
Interventions
Electrofulguration (EF), Nitrofurantoin (NF)
Procedure · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Kansas City, Kansas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 3, 2026, 6:57 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Uqora Supplements in Women With UTIs

NCT04024046
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Uqora, Group1, Group 2
Dietary Supplement
Lead sponsor
Hawthorne Effect Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Sep 3, 2026, 6:57 AM EDT
Withdrawn Phase 2 Interventional

Probiotics for Girls With Recurring Urinary Tract Infections

NCT00789464
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
Lactobacillus reuteri DSM 17938, trimethoprim/sulfamethoxazole
Dietary Supplement · Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Months to 17 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Sep 3, 2026, 6:57 AM EDT
Active, not recruiting Phase 4 Interventional

Preference of Women With Recurrent Urinary Tract Infection for Vaginal Estradiol Tablet vs Cream

NCT05723601
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
Estradiol vaginal cream, Estradiol Vaginal Tablet
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
20 Years to 80 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 3, 2026, 6:57 AM EDT