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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Reducing Post Traumatic Stress Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders

NCT07783516
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders, Occupational Stress, Emotional Regulation Difficulties, Anger Problems, Relational Problems, Irritability
Interventions
Brazilian Jiu-Jitsu Program
Behavioral
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Conroe, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury

NCT06150196
View directory record Official record
Conditions
Brain Injury Traumatic Mild, Post-traumatic Stress Disorder
Interventions
Mindfulness-based Stress Reduction class, Brain Health Education class
Behavioral
Lead sponsor
East Bay Institute for Research and Education
Other
Eligibility
18 Years to 75 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU)

NCT00186472
View directory record Official record
Conditions
Anxiety, Acute Stress Disorder, Posttraumatic Stress Disorder, Depression
Interventions
Brief Cognitive Behavioral Treatment
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2011 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Risk Reduction for Drug Use and Sexual Revictimization

NCT00998153
View directory record Official record
Conditions
Risk Reduction Through Family Therapy, Usual Care
Interventions
Risk Reduction through Family Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Phase 2 Interventional

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

NCT06636786
View directory record Official record
Conditions
Acute Stress Reaction, Acute Stress Disorder, Neurocognitive Function, Post-traumatic Stress
Interventions
Cyclobenzaprine HCl, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
Birmingham, Alabama • Indianapolis, Indiana • Kansas City, Kansas + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Neural Correlates of PTSD Prevention With Mindfulness Based Stress Reduction (MBSR) in Iraqi Veterans

NCT01058031
View directory record Official record
Conditions
Stress Disorders, Posttraumatic, PTSD
Interventions
MBSR
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 4, 2013 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Ending Self Stigma for PTSD

NCT02734212
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Ending Self Stigma for PTSD, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 25, 2026, 9:10 AM EDT
Terminated Phase 1Phase 2 Interventional

Reducing Risk and Trauma-Related Stress in Persons Living With HIV

NCT00186030
View directory record Official record
Conditions
HIV, PTSD
Interventions
HIV Skills-based Prevention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
102 participants
Timeline
2003 – 2004
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2006 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Cardiac Health of Adults With Trauma

NCT05700201
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Lifestyle / Healthy Behavior Intervention, standard care
Behavioral · Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Active, not recruiting Not applicable Interventional

The Group Risk Reduction Intervention Therapy (GRRIT) Project

NCT05401838
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression, Anxiety, PTSD
Interventions
Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group
Behavioral
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
18 Years to 99 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)

NCT01641146
View directory record Official record
Conditions
HIV, Depression, Posttraumatic Stress Disorder
Interventions
Enhanced Sexual Health Intervention for Men (ES-HIM), Health Promotion (HP) Comparison Arm
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
4
States / cities
Inglewood, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2016 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

NCT05624931
View directory record Official record
Conditions
Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
Interventions
Brief CBT-Based Intervention, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
15 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Safety Aid Reduction Treatment for PTSD Among Veterans

NCT04515784
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Safety Aid Reduction Treatment for PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

NCT06957067
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 2 Interventional

Relationship Between the Biological and Psychological Correlates of PTSD

NCT00183300
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Phase 4 Interventional

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

NCT06903819
View directory record Official record
Conditions
Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression, Post-traumatic Stress Disorder (PTSD)
Interventions
Ketamine, standard general anesthesia
Drug
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault

NCT04334356
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mobile Web App
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Colorado Springs, Colorado • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Sep 25, 2026, 9:10 AM EDT
Terminated Not applicable Interventional

Blood Pressure, Heart Rate Variability & Sleep in Veterans With PTSD

NCT01920451
View directory record Official record
Conditions
Insomnia, Posttraumatic Stress Disorder, Hypertension, Cardiovascular Disease
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTI)
Behavioral
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Mobile Mindfulness to Improve Psychological Distress After Critical Illness

NCT02701361
View directory record Official record
Conditions
Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder, Informal Caregivers, Family Members
Interventions
mobile mindfulness, standard mindfulness, education
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Durham, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Terminated Not applicable Interventional

New Beginnings Following Trauma

NCT05817344
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Opioid Use Disorder
Interventions
Written Exposure Therapy - Integrated
Behavioral
Lead sponsor
Jesse McCann
Other
Eligibility
18 Years to 100 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Communication and Support in the Pediatric Intensive Care Unit

NCT02144779
View directory record Official record
Conditions
Reducing Post Traumatic Stress
Interventions
Assigned to palliative care team, Usual Care
Behavioral
Lead sponsor
Ross Hays
Other
Eligibility
18 Years to 90 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 25, 2026, 9:10 AM EDT
Not listed Not applicable Interventional

The Periviable Birth Plan

NCT03061864
View directory record Official record
Conditions
Pregnancy, High Risk, Parturition Complication as Antepartum Condition, Anxiety, PTSD, PreTerm Birth
Interventions
Periviable Birth Plan
Behavioral
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Integrative Risk Reduction and Treatment for Teen Substance Use Problems and PTSD

NCT01751035
View directory record Official record
Conditions
PTSD, Alcohol Use Disorders, Substance Use Disorders
Interventions
Risk Reduction through Family Therapy, Treatment as Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years to 18 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Phase 2 Interventional

BXCL501 After Stress to Increase Recovery Success

NCT06943404
View directory record Official record
Conditions
Acute Stress Reaction, Acute Stress Disorder, Post-traumatic Stress Disorder
Interventions
BXCL501 (dexmedetomidine HCl), Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
3
States / cities
Jacksonville, Florida • St Louis, Missouri • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 25, 2026, 9:10 AM EDT