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ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:50 PM EDT

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Showing 1–24 of 1,893 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Reduction, Weight Clear all
Completed Not applicable Interventional

Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome

NCT00129792
View directory record Official record
Conditions
Metabolic Syndrome X, Prediabetic State, Insulin Resistance, Obesity, Metabolic Diseases
Interventions
Dietary supplement for weight loss, Education and counseling for weight loss
Drug · Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 60 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Oct 20, 2026, 4:50 PM EDT
Not listed Not applicable Interventional

Creating an Optimized Technology-Based Weight Loss Program for Cardiac Rehabilitation Patients

NCT03845283
View directory record Official record
Conditions
Cardiovascular Diseases, Obesity
Interventions
Online Behavioral Weight Loss Program, Physical Activity Intervention, Bite Counter, Virtual Reality, Virtual Meetings
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity

NCT01814072
View directory record Official record
Conditions
Weight Loss
Interventions
12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician, Text Messages, Recommendations to use meal replacements, Buddy Training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Cryovagotomy Diabetes Trial

NCT04276051
View directory record Official record
Conditions
Diabetes Type 2, Diabetes Mellitus, Obesity
Interventions
Cryoablation of the Vagus Nerve, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Emory University
Other
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Atlanta, Georgia • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Preventing Obesity in Military Communities, Adolescents

NCT02334202
View directory record Official record
Conditions
Obesity, Weight Gain, Disordered Eating, Eating Disorder
Interventions
Interpersonal Psychotherapy-Weight Gain, Health Education
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Shared Medical Appointments for Weight Loss

NCT04866966
View directory record Official record
Conditions
Obesity
Interventions
Shared medical appointments for weight loss
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 74 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2021 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors

NCT01482702
View directory record Official record
Conditions
Overweight, Postmenopausal, Breast Cancer
Interventions
weight loss intervention, Weight Loss
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 20, 2026, 4:50 PM EDT
Recruiting Phase 4 Interventional

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

NCT07213466
View directory record Official record
Conditions
Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity, Weight Loss, GLP - 1
Interventions
Group Therapy Program, semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination)
Behavioral · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 20, 2026, 4:50 PM EDT
Completed No phase listed Observational

Protocol for the Assessment of Variability in Histology and Gene Expression in Bariatric Surgery Patients.

NCT00280527
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 20, 2011 · Synced Oct 20, 2026, 4:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ripple Effect of Lifestyle Intervention During Pregnancy on Partners' Weight

NCT01770028
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
3
States / cities
San Luis Obispo, California • New York, New York • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional

A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors

NCT02681965
View directory record Official record
Conditions
Breast Cancer Survivorship, Obesity
Interventions
LEAN book/videos
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 79 Years · Female only
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Arthritis Pilot for Preserving Muscle While Losing Weight

NCT02239939
View directory record Official record
Conditions
Obesity, Osteoarthritis
Interventions
Vest, Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 79 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Weight Management Study

NCT00851201
View directory record Official record
Conditions
Obesity, Diabetes
Interventions
Intensive lifestyle, Standard intervention
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 12 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Oct 20, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

More Outside Your Door: a Diet/physical Activity Intervention to Decrease Risk of Obesity in Alaska Native Preschoolers

NCT06303544
View directory record Official record
Conditions
Child Obesity
Interventions
Wedge 1
Behavioral
Lead sponsor
Alaska Native Tribal Health Consortium
Other
Eligibility
3 Years to 5 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Legume Diet Satiety Pilot Study

NCT02269631
View directory record Official record
Conditions
Obesity, Colorectal Carcinoma
Interventions
Legume diet group, Control diet group, Smartpill, legumes
Behavioral · Device · Other
Lead sponsor
Emory University
Other
Eligibility
40 Years to 70 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 25, 2019 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telephone Counseling and Numberless Scales to Overcome Barriers to Adolescent Weight Loss

NCT04241939
View directory record Official record
Conditions
Obesity
Interventions
Numberless BDS, Digital Scale, Modified Motivational Interviewing
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
12 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
League City, Texas • Webster, Texas
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Wellness Achieved Through Changing Habits (The WATCH Study)

NCT03284788
View directory record Official record
Conditions
Weight Loss, Obesity, Overweight
Interventions
ABT Weight Loss Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
14 Years to 19 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 20, 2026, 4:50 PM EDT
Recruiting Phase 2 Interventional

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

NCT07837973
View directory record Official record
Conditions
Overweight , Obesity, Adults
Interventions
ALV-100, Placebo
Drug
Lead sponsor
Alveus Therapeutics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
20
States / cities
Birmingham, Alabama • Sun City, Arizona • Tempe, Arizona + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Support and Tracking to Achieve Results (Project STAR)

NCT04116853
View directory record Official record
Conditions
Obesity
Interventions
ADAPTIVE Extended-Care Program, STATIC Extended-Care Program
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss on the Web: A Pilot Study Comparing a Commercial Website to a Structured Behavioral Intervention

NCT00263172
View directory record Official record
Conditions
Obesity, Diet Therapy, Weight Loss
Interventions
behavior modification for weight loss
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 22, 2010 · Synced Oct 20, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Study of an International Commercial Program on Weight Loss and Health Outcomes

NCT03571893
View directory record Official record
Conditions
Weight Loss, Weight Change, Body, Obesity, Diet Modification
Interventions
Weight Watchers Freestyle (Flex), DIY Personal Plan
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 20, 2026, 4:50 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

TARGETing Healthy Weight Loss in the Context of Food Insecurity

NCT05601804
View directory record Official record
Conditions
Obesity, Food Insecurity, Food Security, Body Weight
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 20, 2026, 4:50 PM EDT
Not yet recruiting Not applicable Interventional

Optimization of Dietary Adherence in a Mobile Weight Loss Intervention

NCT07582536
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
Core, Switch to Simplified Diet Monitoring, Goal Autonomy/Planning, Just-in-time (JIT) Messaging, Coach Sessions
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 20, 2026, 4:50 PM EDT
Not yet recruiting Phase 4 Interventional

Comparing Different Medication Regimens to Maintaining Weight Loss Among Adults With Obesity Using GLP-1s

NCT07832084
View directory record Official record
Conditions
Obesity & Overweight, Cardiometabolic Health Indicators
Interventions
GLP-1 dose reduction, non-GLP weight loss medication, Maintenance of GLP-1 dose, Resistance exercise regimen, Lifestyle/nutrition counseling
Drug · Behavioral
Lead sponsor
Jing Luo
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 20, 2026, 4:50 PM EDT