Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:00 PM EDT

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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Conditions
Refractive Ametropia
Interventions
etafilcon A control lens (1DM), etafilcon A with print and PVP for light eyes (EALE), etafilcon A with print and PVP for dark eyes (EADE)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 34 Years · Female only
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
15
States / cities
Mission Viejo, California • Pismo Beach, California • Sarasota, Florida + 11 more
Completed Not applicable Interventional Results available

Dispensing Study for the Phenacite Project

NCT02436005
Conditions
Ametropia
Interventions
Phenacite, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Ametropia
Interventions
Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Ocoee, Florida • State College, Pennsylvania
Conditions
Refractive Ametropia, Hyperopia, Myopia
Interventions
Lotrafilcon A spherical contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Timeline
2023
U.S. locations
4
States / cities
Tallahassee, Florida • Franklin Park, Illinois • Eden Prairie, Minnesota + 1 more
Completed Not applicable Interventional Results available

Clinical Biocompatibility Evaluation of Contact Lens Coatings

NCT03034928
Conditions
Refractive Errors, Ametropia
Interventions
Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS, Contact lens with investigational coating 2
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Johns Creek, Georgia
Conditions
Refractive Ametropia
Interventions
BL-3100-NBR03 multi-purpose solution, renu® Advanced Formula multi-purpose solution
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
19
States / cities
San Diego, California • San Francisco, California • Denver, Colorado + 16 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

1-Week Dispensing Evaluation of REVIVE™ Toric Soft Contact Lenses

NCT06053736
Conditions
Refractive Ametropia, Astigmatism
Interventions
REVIVE Toric Soft Contact Lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Rochester, New York
Conditions
Refractive Errors, Ametropia, Astigmatism
Interventions
Verofilcon A toric contact lenses, Etafilcon A toric contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
8
States / cities
Los Angeles, California • Oakland, California • Orlando, Florida + 4 more
Conditions
Ametropia, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 45 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 2 more
Completed No phase listed Observational Accepts healthy volunteers

Comparing Vision Tests in a Virtual Reality Headset to Existing Analogues

NCT04714424
Conditions
Ptosis, Macular Degeneration, Ametropia
Interventions
Virtual Reality Headset
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Conditions
Ametropia, Refractive Error
Interventions
AVA lenses, Standard lenses
Device
Lead sponsor
Essilor International
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Refractive Ametropia
Interventions
LID015385 soft contact lenses, Comfilcon A soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
675 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
42
States / cities
Campbell, California • Fullerton, California • Los Angeles, California + 34 more
Completed Not applicable Interventional Results available

Comparison of Two Daily Disposable Lenses

NCT04013789
Conditions
Refractive Ametropia, Myopia
Interventions
DACP FreshTech contact lenses, DACP contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 35 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Toric Contact Lenses on Current Toric Wearers

NCT00639379
Conditions
Ametropia
Interventions
senofilcon A toric, alphafilcon A toric
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
7
States / cities
Jacksonville, Florida • Orlando, Florida • Morrow, Georgia + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Characterization of Symptomatic Populations

NCT03319212
Conditions
Ametropia
Interventions
senofilcon A contact lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Astigmatism, Ametropia, Myopia
Interventions
Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
11
States / cities
Los Angeles, California • Longwood, Florida • Maitland, Florida + 8 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Contact Lenses With Experimental Dye on Visual Function

NCT03556579
Conditions
Ametropia
Interventions
senofilcon A with new UV blocker, senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Statesboro, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Study of Soft Contact Lens Use With 7 Day Extended Wear

NCT00597467
Conditions
Ametropia
Interventions
VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
23
States / cities
La Mesa, California • San Diego, California • Santa Monica, California + 17 more
Completed Not applicable Interventional

Optimization for Toric Contact Lenses

NCT07557030
Conditions
Astigmatism, Ametropia
Interventions
Lens 1 ( stenfilcon A ), Lens 2 ( comfilcon A )
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Refractive Ametropia
Interventions
etafilcon A with print and PVP for dark eyes (EAPVPDE), etafilcon A control lens (EADE)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 34 Years · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
6
States / cities
Bloomfield, Connecticut • Tallahassee, Florida • Overland Park, Kansas + 3 more
Conditions
Refractive Ametropia
Interventions
Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
15
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 11 more
Conditions
Ametropia
Interventions
Sapphire, Pearl
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
6
States / cities
San Diego, California • Torrance, California • Denver, North Carolina + 3 more
Conditions
Myopia, Ametropia
Interventions
Verofilcon A contact lenses, Kalifilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
4
States / cities
Maitland, Florida • Orlando, Florida • Eden Prairie, Minnesota + 1 more
Conditions
Refractive Errors, Ametropia, Myopia
Interventions
Delefilcon A contact lenses, Kalifilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
8
States / cities
Orlando, Florida • Tallahassee, Florida • Bloomington, Illinois + 4 more