Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 268 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dispensing Evaluation of Investigational Contact Lenses

NCT02625220
Conditions
Myopia; Astigmatism
Interventions
Prototype toric lens senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
12
States / cities
Jacksonville, Florida • Pembroke Pines, Florida • Winter Park, Florida + 9 more
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation Study on Corneal Lens for Vision Correction

NCT02053688
Conditions
Astigmatism
Interventions
Astigmatic Correction Lens (Nexis ACCL lenses), Toric Soft Contact Lenses
Device
Lead sponsor
FORSIGHT Vision3
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
6
States / cities
Fremont, California • Livermore, California • Menlo Park, California + 2 more
Completed Not applicable Interventional Results available

Clinical Investigation of the WaveLight® EX500 Excimer Laser

NCT04805593
Conditions
Hyperopia, Hyperopic Astigmatism
Interventions
WaveLight EX500 excimer laser system, LASIK
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Overland Park, Kansas • Kansas City, Missouri • Greensboro, North Carolina + 2 more
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
8
States / cities
Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors

NCT01675479
Conditions
Hyperopia
Interventions
LASIK correction of hyperopic refractive errors
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
9
States / cities
Los Angeles, California • Miami, Florida • Chicago, Illinois + 6 more
Conditions
Cataract Extraction, Refractive Surgery
Interventions
aspheric ReSTOR multifocal intraocular lens (IOL)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Apioc Contact Lens Feasibility

NCT03688672
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism, Presbyopia
Interventions
Apioc Contact Lens Design
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle

NCT01234207
Conditions
Presbyopia
Interventions
Standard, non-free-form, non-customized PAL spectacles, Individually customized free-form surfaced PAL spectacles
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
39 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Berkeley, California
Completed Not applicable Interventional Results available

Vivity IOL: Emmetropia Compared to Monovision.

NCT05464732
Conditions
Presbyopia
Interventions
Vivity IOL emmetropia, Vivity IOL monovision
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Conditions
Axial Myopia, Refractive Errors
Interventions
Oral Riboflavin
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
6 Years to 12 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Cataract, Dry Eye
Interventions
Not listed
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rockville Centre, New York
Conditions
Presbyopia Condition
Interventions
Test lens, Control lens
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
45 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software

NCT05389072
Conditions
Myopia
Interventions
control contact lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
6 Years to 35 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
San Diego, California • Glenview, Illinois • Bellaire, Texas
Conditions
Refractive Errors
Interventions
DT1 Toric contact lenses, AO1DfA contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Maitland, Florida • Eden Prairie, Minnesota
Conditions
Presbyopia
Interventions
UNR844, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
45 Years to 55 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
12
States / cities
Laguna Hills, California • Newport Beach, California • Largo, Florida + 8 more
Completed Not applicable Interventional

Comparison of LASIK and SBK

NCT00714363
Conditions
Myopia
Interventions
LASIK, SBK
Procedure
Lead sponsor
University of Utah
Other
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Myopia, Hyperopia
Interventions
Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Athens, Ohio + 1 more
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more
Conditions
Myopia
Interventions
B&L RD2135-01 lens C, B&L RD2135-01 lens D, PureVision2, Air Optix Aqua
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens

NCT06044948
Conditions
Refractive Errors
Interventions
Delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
6
States / cities
Tallahassee, Florida • Eden Prairie, Minnesota • Garner, North Carolina + 3 more
Completed Not applicable Interventional Accepts healthy volunteers

Study of Soft Contact Lens Use With 7 Day Extended Wear

NCT00597467
Conditions
Ametropia
Interventions
VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
23
States / cities
La Mesa, California • San Diego, California • Santa Monica, California + 17 more
Completed Not applicable Interventional Results available

Safety and Efficacy of a Contact Lens for Daily Disposable Use

NCT01365039
Conditions
Myopia
Interventions
Test, daily disposable contact lens, SofLens daily disposable contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 40 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of DW Silicone Hydrogel Lens Compared to DW Silicone Hydrogel Lens

NCT01386008
Conditions
Myopia
Interventions
senfilcon A contact lens, investigational enfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Berkeley, California
Conditions
Refractive Errors, Myopia
Interventions
LID220365 contact lens, LID006961 contact lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Maitland, Florida • Orlando, Florida • Franklin Park, Illinois + 4 more