Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jun 25, 2026, 10:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 264 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Refractive Assessment Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients

NCT01373580
View directory record Official record
Conditions
Presbyopia
Interventions
The Raindrop Near Vision Inlay
Device
Lead sponsor
ReVision Optics, Inc.
Industry
Eligibility
35 Years to 65 Years
Enrollment
373 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
11
States / cities
Camarillo, California • Laguna Hills, California • Newport Beach, California + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens

NCT05211739
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
7
States / cities
Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Jun 25, 2026, 10:18 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

ACRYSOF® Restor Apodized Diffractive IOL Postmarket Evaluation of Clinical Outcomes and Life-Style Visual Performance RESTOR IOL SN60WF IOL (Control Group)

NCT00345111
View directory record Official record
Conditions
Refractive Assessment
Interventions
Clinical visual outcomes of bilateral implantation of Restore Intra Ocular Lens.
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the CooperVision, Inc. Fanfilcon A and Enfilcon A Daily Wear Contact Lenses When Used for Frequent Replacement for up to One (1) Month of Daily Wear

NCT02555722
View directory record Official record
Conditions
Myopia
Interventions
fanfilcon A (test), enfilcon A (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
6
States / cities
San Diego, California • Torrance, California • Denver, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

Insertion Clinical Study to Evaluate the Orientation Characteristics of Multiple Kalifilcon A Daily Disposable Toric LD213001 Contact Lenses

NCT05129124
View directory record Official record
Conditions
Astigmatism
Interventions
kalifilcon A Daily Disposable Toric LD213001 Contact Lenses, Commercially available Ultra for Astigmatism Contact Lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia

NCT05431543
View directory record Official record
Conditions
Presbyopia, Refractive Errors, Eye Diseases
Interventions
Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle proprietary ophthalmic solution
Drug
Lead sponsor
LENZ Therapeutics, Inc
Other
Eligibility
45 Years to 75 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Chandler, Arizona • Glendale, California • Andover, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens

NCT04178720
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
8
States / cities
Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia

NCT03201562
View directory record Official record
Conditions
Presbyopia
Interventions
Aceclidine+tropicamide combination, Aceclidine, Vehicle
Drug
Lead sponsor
LENZ Therapeutics, Inc
Other
Eligibility
48 Years to 64 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Three Basic Progressive Lens Designs

NCT05252871
View directory record Official record
Conditions
Presbyopia
Interventions
Progressive Additional Lenses (PAL), pre calibrated and made of polymeric material with anti-reflection coating
Device
Lead sponsor
Western University of Health Sciences
Other
Eligibility
45 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Jun 25, 2026, 10:18 PM EDT
Terminated Not applicable Interventional Results available

A Study Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets

NCT03326869
View directory record Official record
Conditions
Presbyopia
Interventions
Raindrop Near Vision Inlay
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
41 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Aug 9, 2020 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Phase 2 Interventional

Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia

NCT02554396
View directory record Official record
Conditions
Presbyopia
Interventions
PRX-100, Placebo
Drug
Lead sponsor
LENZ Therapeutics, Inc
Other
Eligibility
45 Years to 59 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2017 · Synced Jun 25, 2026, 10:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A 6 Month Study to Evaluate the Safety, Analgesic Efficacy of ACUVAIL™ (Ketorolac Tromethamine Ophthalmic Solution) 0.45%, in Post-PRK Corneal Wound Healing

NCT01193231
View directory record Official record
Conditions
Must be PRK Candidate
Interventions
Not listed
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years to 39 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Jun 25, 2026, 10:18 PM EDT
Active, not recruiting Not applicable Interventional

Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear

NCT06009458
View directory record Official record
Conditions
Myopia
Interventions
Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Device
Lead sponsor
Acuity Polymers, Inc.
Industry
Eligibility
7 Years and older
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
9
States / cities
Mission Viejo, California • Oakland, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Epi-lasik in U.S. Army Personnel

NCT00413517
View directory record Official record
Conditions
Myopia
Interventions
Epi-Lasik
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 15, 2010 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia

NCT06542497
View directory record Official record
Conditions
Presbyopia
Interventions
0.75% phentolamine ophthalmic solution, Placebo
Drug
Lead sponsor
Ocuphire Pharma, Inc.
Industry
Eligibility
45 Years to 64 Years
Enrollment
569 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
39
States / cities
Chandler, Arizona • Mesa, Arizona • Phoenix, Arizona + 32 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jun 25, 2026, 10:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Assessment of Visual Performance in Patients With Low Levels of Astigmatism

NCT00842231
View directory record Official record
Conditions
Cataract Extraction, Corneal Astigmatism
Interventions
Visual performance measures
Other
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2010 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight

NCT04693260
View directory record Official record
Conditions
Myopia
Interventions
Visual Acuity with a Hand-held Device Supported by Mobile App.
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
7 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Santa Clara, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Jun 25, 2026, 10:18 PM EDT
Terminated No phase listed Interventional Results available

A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus

NCT04177771
View directory record Official record
Conditions
Aphakia, Cataract, Presbyopia
Interventions
Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use

NCT05166902
View directory record Official record
Conditions
Ametropia
Interventions
Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Ocoee, Florida • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens

NCT01518868
View directory record Official record
Conditions
Presbyopia
Interventions
Investigational contact lens, PureVision contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2020 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Stenfilcon A Soft Contact Lens When Compared to Ocufilcon B Soft Contact Lens

NCT01354223
View directory record Official record
Conditions
Myopia
Interventions
stenfilcon A contact lens, ocufilcon B contact lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
4
States / cities
San Diego, California • East Lansing, Michigan • Beachwood, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Jun 25, 2026, 10:18 PM EDT
Completed No phase listed Observational

Prospective Evaluation of a Smartphone Application, GoCheckKids™, to Detect Amblyopia Risk Factors in Young Children

NCT03447171
View directory record Official record
Conditions
Amblyopia
Interventions
App Vision Screening
Device
Lead sponsor
Gobiquity Mobile Health
Industry
Eligibility
1 Year to 8 Years
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Jun 25, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens

NCT04585646
View directory record Official record
Conditions
Myopia
Interventions
Orion daily disposable contact lens, Gemini daily disposable contact lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Jun 25, 2026, 10:18 PM EDT