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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Refractive Error - Myopia Clear all
Completed Phase 3 Interventional

Correction of Myopia Evaluation Trial (COMET)

NCT00000113
View directory record Official record
Conditions
Myopia
Interventions
Progressive Addition Lenses, single vision lenses
Other
Lead sponsor
Stony Brook University
Other
Eligibility
6 Years to 12 Years
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2013
U.S. locations
4
States / cities
Birmingham, Alabama • Boston, Massachusetts • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 17, 2026, 9:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

NCT06034327
View directory record Official record
Conditions
Myopia, Juvenile Myopia, Myopia Progression
Interventions
Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
14
States / cities
Oakland, California • San Diego, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2025 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 1

NCT04527978
View directory record Official record
Conditions
Refractive Errors, Myopia
Interventions
Verofilcon A contact lenses, Nesofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
4
States / cities
Maitland, Florida • Medina, Minnesota • Powell, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Product Feasibility of a New Silicone Hydrogel Contact Lens

NCT01309100
View directory record Official record
Conditions
Myopia
Interventions
Investigational Lens, Acuvue Oasys Lens, Air Optix Aqua Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2014 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Dispensing Evaluation of Printed Etafilcon A With Polyvinylpyrrolidone (PVP)

NCT01180777
View directory record Official record
Conditions
Myopia
Interventions
etafilcon A (A), etafilcon A (B), etafilcon A (C)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
6
States / cities
Cupertino, California • Los Angeles, California • San Jose, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Efficacy of PEG-400 and Systane Artificial Tears (Alcon) on Quality of Vision

NCT00627302
View directory record Official record
Conditions
Myopia
Interventions
PEG-400, Systane
Drug
Lead sponsor
Bp Consulting, Inc
Network
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Rockville Centre, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2008 · Synced Sep 17, 2026, 9:35 PM EDT
Not listed Phase 4 Interventional

A Study to Evaluate the Raindrop Near Vision Inlay Under Flap or Within Pocket

NCT03376412
View directory record Official record
Conditions
Presbyopia
Interventions
Raindrop Near Vision Inlay
Device
Lead sponsor
Whitten Laser Eye
Other
Eligibility
40 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 17, 2017 · Synced Sep 17, 2026, 9:35 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software

NCT05389072
View directory record Official record
Conditions
Myopia
Interventions
control contact lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
6 Years to 35 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
San Diego, California • Glenview, Illinois • Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2022 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Assessment of Two Manufacturing Processes

NCT04126057
View directory record Official record
Conditions
Juvenile Myopia
Interventions
SightGlass Vision DOT Spectacle Lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 14 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
5
States / cities
Longwood, Florida • Pittsburg, Kansas • Raytown, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours

NCT03881670
View directory record Official record
Conditions
Hyperopia, Myopia
Interventions
Lotrafilcon B, lotrafilcon B with Hydraluxe
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Light on the Choroid and Pupil

NCT05852782
View directory record Official record
Conditions
Emmetropia, Myopia
Interventions
White Light therapy, Blue light therapy, Red light therapy, Darkness
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults

NCT05114486
View directory record Official record
Conditions
Presbyopia
Interventions
Pilocarpine Ophthalmic administered with the Optejet dispenser, Placebo administered with the Optejet dispenser
Combination Product
Lead sponsor
Eyenovia Inc.
Industry
Eligibility
40 Years to 55 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
9
States / cities
San Diego, California • Fairfield, Connecticut • Louisville, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced Sep 17, 2026, 9:35 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

An Evaluation of LASIK, SMILE and PRK Surgery in Physicians

NCT02576483
View directory record Official record
Conditions
Nearsightedness, Farsightedness, Astigmatism
Interventions
Questionnaire (QoV questionnaire)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 62 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Performance of a New Silicone Hydrogel Contact Lens

NCT01873846
View directory record Official record
Conditions
Myopia
Interventions
Silicone Hydrogel Contact Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 35 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Madison, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens

NCT03971227
View directory record Official record
Conditions
Refractive Errors
Interventions
Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens
Device
Lead sponsor
Acuity Polymers, Inc.
Industry
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Honolulu, Hawaii • Edina, Minnesota • Pittsford, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Performance of Monthly Replacement Sphere Lens Designs in Habitual Soft Contact Lens Wearers

NCT05114564
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Athens, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Performance of 59% Hioxifilcon A vs. Marketed Hydrogel Contact Lenses in Habitual Hydrogel Wearers

NCT04986644
View directory record Official record
Conditions
Refractive Error - Myopia Bilateral
Interventions
Hioxifilcon A standard hydrogel contact lens with Hyaluronic Acid (HA)
Device
Lead sponsor
Vision Service Plan
Industry
Eligibility
18 Years to 42 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
2
States / cities
Atlanta, Georgia • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism

NCT04883099
View directory record Official record
Conditions
Presbyopia, Myopia, Hyperopia, Astigmatism
Interventions
APIOC for Presbyopia and APIOC for Presbyopia for Astigmatism
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
6
States / cities
San Diego, California • Orlando, Florida • Lexington, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses

NCT05959200
View directory record Official record
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Lens Fitting Evaluation of CooperVision MyDay™ Compared With 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®

NCT02341859
View directory record Official record
Conditions
Myopia
Interventions
stenfilcon A, delefilcon A, narafilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Sep 17, 2026, 9:35 PM EDT
Completed No phase listed Observational

Swept Source OCT Imaging With the DREAM VG-OCT

NCT05876689
View directory record Official record
Conditions
Eye Diseases, Myopia, Glaucoma
Interventions
DREAM OCT
Device
Lead sponsor
Robert T. Chang, MD
Other
Eligibility
18 Years and older
Enrollment
154 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced Sep 17, 2026, 9:35 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control

NCT05477875
View directory record Official record
Conditions
Photorefractive Keratectomy, Myopia, Hyperopia
Interventions
oral cannabinoid, oral codeine/acetaminophen
Drug · Combination Product
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 17, 2026, 9:35 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Euclid Phoenix Lens Design Trial 2

NCT06392607
View directory record Official record
Conditions
Myopia, Cornea
Interventions
Euclid orthokeratology (standard coating), Euclid orthokeratology (enhanced coating)
Device
Lead sponsor
Euclid Systems Corporation
Industry
Eligibility
6 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
5
States / cities
Edina, Minnesota • Sartell, Minnesota • North Brunswick, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Sep 17, 2026, 9:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A 6 Month Study to Evaluate the Safety, Analgesic Efficacy of ACUVAIL™ (Ketorolac Tromethamine Ophthalmic Solution) 0.45%, in Post-PRK Corneal Wound Healing

NCT01193231
View directory record Official record
Conditions
Must be PRK Candidate
Interventions
Not listed
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years to 39 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Sep 17, 2026, 9:35 PM EDT