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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Refractive Error - Myopia Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers

NCT03585790
View directory record Official record
Conditions
Asthenopia, Myopia
Interventions
Contact lens with Multifocal Optics, Contact lens with Single Vision Optics
Device
Lead sponsor
Pete Kollbaum, OD, PhD
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults

NCT05114486
View directory record Official record
Conditions
Presbyopia
Interventions
Pilocarpine Ophthalmic administered with the Optejet dispenser, Placebo administered with the Optejet dispenser
Combination Product
Lead sponsor
Eyenovia Inc.
Industry
Eligibility
40 Years to 55 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
9
States / cities
San Diego, California • Fairfield, Connecticut • Louisville, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight

NCT04693260
View directory record Official record
Conditions
Myopia
Interventions
Visual Acuity with a Hand-held Device Supported by Mobile App.
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
7 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Santa Clara, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Feasibility of Two New Silicone Hydrogel Contact Lenses

NCT01583868
View directory record Official record
Conditions
Myopia
Interventions
B&L RD2135-01 lens C, B&L RD2135-01 lens D, PureVision2, Air Optix Aqua
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Stenfilcon A Soft Contact Lens When Compared to Ocufilcon B Soft Contact Lens

NCT01354223
View directory record Official record
Conditions
Myopia
Interventions
stenfilcon A contact lens, ocufilcon B contact lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
4
States / cities
San Diego, California • East Lansing, Michigan • Beachwood, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Comfilcon A and Senofilcon A Lenses

NCT01695369
View directory record Official record
Conditions
Myopia
Interventions
Senofilcon A; Comfilcon A, Comfilcon A; Senofilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

1-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for Astigmatism

NCT05320042
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
kalifilcon A Daily Disposable Toric, Ultra for Astigmatism Contact Lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Echothiophate Iodide for the Prevention of Progression of Myopia

NCT02544529
View directory record Official record
Conditions
Myopia
Interventions
Echothiophate Iodide 0.03% Ophthalmic Solution, Carboxymethylcellulose Sodium (0.5%)
Drug
Lead sponsor
Danbury Eye Physicians & Surgeons, PC
Other
Eligibility
9 Years to 15 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Danbury, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Results available

Comparative Performance of PureVision, Acuvue Oasys and O2Optix

NCT00640341
View directory record Official record
Conditions
Myopia
Interventions
PureVision Contact Lens, Acuvue Oasys Contact Lens, O2Optix Contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
510 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 11, 2011 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Evaluating NeuroVision's Neural Vision Correction (NVC) Myopia Treatment

NCT00469612
View directory record Official record
Conditions
Myopia
Interventions
NeuroVision's NVC treatment for Low Myopia
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 59 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin

NCT02347631
View directory record Official record
Conditions
Soft Contact Lenses, Myopia
Interventions
Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 38 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed No phase listed Observational Results available

Daily Disposable Performance of 1•DAY ACUVUE® TruEye™ and 1•DAY ACUVUE® MOIST® With LACREON® TECHNOLOGY

NCT01467557
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
narafilcon B daily disposable soft contact lenses, etafilcon A daily disposable soft contact lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
8 Years and older
Enrollment
1,171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
37
States / cities
Campbell, California • Fullerton, California • Huntington Beach, California + 29 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Jul 22, 2026, 2:08 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

An Evaluation of LASIK, SMILE and PRK Surgery in Physicians

NCT02576483
View directory record Official record
Conditions
Nearsightedness, Farsightedness, Astigmatism
Interventions
Questionnaire (QoV questionnaire)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 62 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Side Effects of Atropine (SEA) Study

NCT03593044
View directory record Official record
Conditions
Myopia
Interventions
0.01% concentration atropine drops
Drug
Lead sponsor
Jeffrey J. Walline, OD PhD
Other
Eligibility
21 Years to 30 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate a Modified Contact Lens

NCT01391364
View directory record Official record
Conditions
Myopia
Interventions
SofLens in investigational solution, SofLens in currently marketed solution
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 40 Years
Enrollment
438 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Performance Assessment of a Modified Daily Disposable Contact Lens

NCT03762668
View directory record Official record
Conditions
Refractive Errors, Myopia, Hyperopia
Interventions
Modified delefilcon A contact lenses, Delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
5
States / cities
Maitland, Florida • Orlando, Florida • West Palm Beach, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dispensing Evaluation of Investigational Contact Lenses

NCT02625220
View directory record Official record
Conditions
Myopia; Astigmatism
Interventions
Prototype toric lens senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
12
States / cities
Jacksonville, Florida • Pembroke Pines, Florida • Winter Park, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2017 · Synced Jul 22, 2026, 2:08 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Myopia Progression With a Novel Extended Depth of Focus Contact Lens

NCT03358862
View directory record Official record
Conditions
Myopia, Myopia, Progressive
Interventions
NaturalVue Multifocal Contact Lens
Device
Lead sponsor
Aller, Thomas A., OD
Other
Eligibility
5 Years to 25 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Bruno, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

A Dispensing Comparison of a Test Daily 1 Day Lens Against a Control 1 Day Lens.

NCT03951610
View directory record Official record
Conditions
Myopia
Interventions
Test lens, Control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Anaheim, California • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses

NCT01309867
View directory record Official record
Conditions
Myopia
Interventions
Investigational Toric Lens, PureVision Toric Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Jul 22, 2026, 2:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effect of Final Exam Preparation on Anxiety Level, Self-Perception, Ocular Symptoms, Accommodation and Vergence in Myopia

NCT00405106
View directory record Official record
Conditions
Myopia
Interventions
Not listed
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
20 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2006 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wavefront-guided PRK vs Wavefront-optimized PRK

NCT02091934
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Wavefront-guided PRK, Wavefront-optimized PRK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multicenter Dispensing Study of Biofinity Lenses in Extended Range

NCT02060539
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
Biofinity XR
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
Berkeley, California • Indianapolis, Indiana • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Jul 22, 2026, 2:08 PM EDT
Completed No phase listed Interventional Results available

A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens

NCT03499067
View directory record Official record
Conditions
Myopia
Interventions
Test lens, Control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Berkeley, California • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Jul 22, 2026, 2:08 PM EDT