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ClinicalTrials.gov public records Last synced Sep 7, 2026, 7:35 AM EDT

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Showing 25–45 of 21 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Refractive Error Correction Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery

NCT04698278
View directory record Official record
Conditions
Cataract, Refractive Errors
Interventions
PanOptix Trifocal Intraocular Lens
Device
Lead sponsor
Parkhurst NuVision Clinical Research LLC
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism

NCT00761826
View directory record Official record
Conditions
Mixed Astigmatism
Interventions
MEL 80 Mixed Astigmatism Treatment
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
5
States / cities
San Diego, California • Greenwood Village, Colorado • Kansas City, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK

NCT00821236
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Excimer Laser, AMO/VISX CustomVue™, LADARVision 4000 excimer laser
Device
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
Overland Park, Kansas • Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Sep 7, 2026, 7:35 AM EDT
Recruiting Phase 4 Interventional

Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery

NCT07140653
View directory record Official record
Conditions
Astigmatism
Interventions
Femto arcs, Light Adjustable Lens (LAL)
Other · Device
Lead sponsor
Center For Sight
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Venice, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

WaveLight® EX500 Excimer Laser System for the Correction of Myopia Using InnovEyes™ in Conjunction With InnovEyes™ Sightmap

NCT04219891
View directory record Official record
Conditions
Myopia
Interventions
WaveLight EX500 excimer laser system with InnovEyes sightmap, LASIK, InnovEyes sightmap
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
9
States / cities
San Diego, California • Indianapolis, Indiana • Chevy Chase, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance of a Silicone Hydrogel Contact Lens Following One Night of Extended Wear

NCT03560141
View directory record Official record
Conditions
Refractive Errors
Interventions
LID011121 contact lens, Comfilcon A contact lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Sep 7, 2026, 7:35 AM EDT
Recruiting Not applicable Interventional

Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses

NCT07218731
View directory record Official record
Conditions
Presbyopia Correction, Presbyopia
Interventions
Multifocal contact lenses, Spherical contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 7, 2026, 7:35 AM EDT
Recruiting Phase 2 Interventional

Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome

NCT07490444
View directory record Official record
Conditions
Refractive Error Correction, Visual Acuity
Interventions
Metric-optimized spectacles, Routine Clinical Spectacles
Device
Lead sponsor
Ohio State University
Other
Eligibility
5 Years to 12 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 7, 2026, 7:35 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

First-Sight Refractive Error Correction: Direct Comparison to Autorefraction Results in Children 7 to 18 Years of Age

NCT01365884
View directory record Official record
Conditions
Refractive Error
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
7 Years to 18 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 27, 2023 · Synced Sep 7, 2026, 7:35 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses

NCT01058629
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
SynergEyes A2 Hybrid Contact Lens
Device
Lead sponsor
SynergEyes, Inc.
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
10
States / cities
Campbell, California • Carlsbad, California • Encino, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2010 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia

NCT00762541
View directory record Official record
Conditions
Myopia
Interventions
MEL 80 Treatment of High Myopia
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
5
States / cities
San Diego, California • Greenwood Village, Colorado • Kansas City, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser

NCT02430428
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Carl Zeiss Meditec VisuMax Femtosecond Laser
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years and older
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
5
States / cities
Greenwood Village, Colorado • Leawood, Kansas • Sioux Falls, South Dakota + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Comparison of Alcon LADARVision Wavefront-guided LASIK Enhancement and Conventional LASIK Enhancement for the Correction of Residual Refractive Errors Following LASIK Procedures

NCT00413881
View directory record Official record
Conditions
Refractive Errors
Interventions
WAVEFRONT- GUIDED LASIK ENHANCEMENT, CONVENTIONAL LASIK ENHANCEMENT
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Sep 7, 2026, 7:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

First-Sight Refractive Error Correction in the Developing World

NCT01598818
View directory record Official record
Conditions
Vision Loss
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
7 Years to 50 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Sep 7, 2026, 7:35 AM EDT
Recruiting Phase 3 Interventional

Phase III Presbyopia Correction Using the VIS Opti-K™ System

NCT06487897
View directory record Official record
Conditions
Presbyopia
Interventions
Optimal laser keratoplasty
Device
Lead sponsor
VIS, Inc.
Industry
Eligibility
40 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Boca Raton, Florida • South Dartmouth, Massachusetts • Teaneck, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Refractive Index Material 510(k)

NCT00766168
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
HDS HI 1.54; pahrifocon A, FluoroPerm 30 RGP; paflufocon C
Other · Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
12 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
8
States / cities
Lake Elsinore, California • Englewood, Colorado • East Lansing, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Sep 7, 2026, 7:35 AM EDT
Completed No phase listed Observational

Accuracy of IOLMASTER 700 Total Keratometry (TK)

NCT05254587
View directory record Official record
Conditions
Myopia, Hyperopia, Cataract
Interventions
IOLMASTER 700 TK
Device
Lead sponsor
Advanced Vision Care
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Bakersfield, California • Los Angeles, California • Torrance, California + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Use of the VisuMax™ Femtosecond Laser

NCT01638390
View directory record Official record
Conditions
Myopia
Interventions
Treatment with the VisuMax™ Femtosecond Laser
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years and older
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
5
States / cities
Greenwood Village, Colorado • Miami, Florida • Leawood, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens

NCT04422990
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
14
States / cities
Los Angeles, California • Novato, California • Oakland, California + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2022 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Not applicable Interventional Results available

Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear

NCT04403542
View directory record Official record
Conditions
Refractive Errors, Myopia, Hyperopia
Interventions
Lehfilcon A contact lens, Comfilcon A contact lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
3
States / cities
Medina, Minnesota • Granville, Ohio • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Sep 7, 2026, 7:35 AM EDT
Completed Phase 3 Interventional

Correction of Myopia Evaluation Trial (COMET)

NCT00000113
View directory record Official record
Conditions
Myopia
Interventions
Progressive Addition Lenses, single vision lenses
Other
Lead sponsor
Stony Brook University
Other
Eligibility
6 Years to 12 Years
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2013
U.S. locations
4
States / cities
Birmingham, Alabama • Boston, Massachusetts • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 7, 2026, 7:35 AM EDT