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ClinicalTrials.gov public records Last synced Sep 3, 2026, 8:16 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Withdrawn Phase 4 Interventional

Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic

NCT01511211
View directory record Official record
Conditions
Pain, Total Knee Arthroplasty
Interventions
Dexamethasone, Ropivacaine
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 11, 2013 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Phase 1Phase 2 Interventional

Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction

NCT00004911
View directory record Official record
Conditions
Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction, Gastric Cancer, Gastrointestinal Carcinoid Tumor, Gastrointestinal Stromal Tumor, Quality of Life, Small Intestine Cancer
Interventions
bowel obstruction management, quality-of-life assessment
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Phase 2 Interventional

Erector Spinae Plane Block vs Local Infiltration Following Fusion Surgery

NCT06199999
View directory record Official record
Conditions
Postoperative Delirium, Pain, Postoperative, Degenerative Disc Disease
Interventions
Erector Spinae Block, Local infiltration with local anesthetic
Procedure
Lead sponsor
Rashmi Mueller
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Optimizing Local Anesthetic Concentration for Continuous Popliteal-Sciatic Nerve Blocks

NCT01898689
View directory record Official record
Conditions
Relatively Healthy Volunteers
Interventions
Ropivacaine 0.1%, Ropivacaine 0.4%
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2021 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A

NCT04797559
View directory record Official record
Conditions
Postoperative Pain, Opioid Use
Interventions
SZMN Block
Procedure
Lead sponsor
Stanford University
Other
Eligibility
6 Months to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: A Pilot Study

NCT03936387
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Ropivacaine
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Years to 21 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 3, 2026, 8:16 PM EDT
Not yet recruiting Not applicable Interventional

Combination Versus Alone Liposomal Bupivacaine Blocks in Minimally Invasive Thoracic Surgery-1

NCT07254650
View directory record Official record
Conditions
Lung Cancer (Diagnosis)
Interventions
Arm 1 "LipoB-I": Liposomal Bupivacaine via Multi-Level Intercostal Nerve Block, Arm 2 "LipoB-S": Liposomal Bupivacaine via Serratus Anterior Plane Block, Arm 3 "LipoB-C": Liposomal Bupivacaine Administered via Combination Block
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 3, 2026, 8:16 PM EDT
Terminated Phase 4 Interventional Results available

Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery

NCT01195103
View directory record Official record
Conditions
Procedural Sedation, Regional Anesthesia Block, Orthopedic Surgery
Interventions
Fospropofol disodium, Placebo + Midazolam, Fentanyl
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 28, 2012 · Synced Sep 3, 2026, 8:16 PM EDT
Enrolling by invitation Not applicable Interventional

Peripheral Regional Blockade and EMG

NCT06982027
View directory record Official record
Conditions
Surgery
Interventions
BlockSynop surface electromyography device, Peripheral nerve block
Device · Procedure
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
0 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 3, 2026, 8:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery

NCT05805423
View directory record Official record
Conditions
Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use
Interventions
bilateral superficial cervical plexus blocks and local wound infiltration, placebo injection and local wound infiltration
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 99 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 3, 2026, 8:16 PM EDT
Completed No phase listed Observational

Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates

NCT01557985
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bupivacaine
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 28 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 3, 2026, 8:16 PM EDT
Terminated Phase 4 Interventional

Pain Management After Total Shoulder Arthroplasty

NCT03219983
View directory record Official record
Conditions
Glenohumeral Arthritis, Total Shoulder Arthroplasty
Interventions
Ropivacaine, liposomal bupivacaine
Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 3, 2026, 8:16 PM EDT
Not listed Not applicable Interventional

TAP Catheters Versus Intrathecal Morphine for Cesarean Section

NCT01593280
View directory record Official record
Conditions
Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Cesarean Section, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions
TAP catheter, intrathecal morphine
Device · Drug
Lead sponsor
Stamford Anesthesiology Services, PC
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2012 · Synced Sep 3, 2026, 8:16 PM EDT
Withdrawn Phase 4 Interventional

Caudal vs. Pudendal Block in Peds GU

NCT05708989
View directory record Official record
Conditions
Hypospadias, Penile Torsion, Chordee, Phimosis
Interventions
Caudal Block, Ultrasound-guided Pudendal Block, Injectable 1 ml/kg of 0.25% ropivacaine with 1mcg/kg dexmedetomidine, Injection of 0.5 ml/kg per side of injectable 0.2-0.3% ropivacaine with 0.5 mcg/kg dexmetomedine.
Procedure · Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
6 Months to 3 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Early Phase 1 Interventional

Erector Spinae Regional Anesthesia for Pain Control

NCT05794828
View directory record Official record
Conditions
Pain Management
Interventions
Bupivacaine Injection
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Ridley Park, Pennsylvania • Upland, Pennsylvania • San Antonio, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Sep 3, 2026, 8:16 PM EDT
Terminated Phase 4 Interventional Results available

Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.

NCT03691935
View directory record Official record
Conditions
Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
Interventions
Ropivacaine, Normal saline
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 3, 2026, 8:16 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery

NCT06806410
View directory record Official record
Conditions
Hand Surgery, Wrist Surgery, Elbow Surgery, Fracture Fixation, Dupuytren Contracture, Finger Fracture, Wrist Arthropathy, Distal Radius Fracture
Interventions
Liposomal bupivacaine (LB), Dexamethasone
Drug
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Phase 1 Interventional Results available

Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery

NCT04908449
View directory record Official record
Conditions
Coronary Artery Disease, Postoperative Pain, Respiratory Failure
Interventions
Rectus sheath block with bupivacaine
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 3, 2026, 8:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparison of Articaine Mandibular Infiltration to Lidocaine Inferior Alveolar Nerve Block in Pediatric Patients

NCT04865848
View directory record Official record
Conditions
Anesthesia
Interventions
Dental local anesthesia
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
4 Years to 10 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Sep 3, 2026, 8:16 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Defining the Optimal Location to Place an Adductor Canal Block

NCT04298476
View directory record Official record
Conditions
Knee Arthropathy
Interventions
Placement of an adductor canal nerve block
Procedure
Lead sponsor
Drexel University
Other
Eligibility
7 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 3, 2026, 8:16 PM EDT
Terminated Phase 4 Interventional Results available

A Study of Loco-Regional Liposomal Bupivacaine Injection

NCT05992896
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Bupivacaine liposome, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Eau Claire, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of the STAR Maneuver on UGRA Training

NCT02032420
View directory record Official record
Conditions
Simulator-based Training of Ultrasound-guided Regional Anesthesia
Interventions
STAR, ART
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Not applicable Interventional

Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery

NCT03807505
View directory record Official record
Conditions
Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Shoulder Injury
Interventions
Interscalene brachial plexus nerve block, Erector spinae plane block
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Sep 3, 2026, 8:16 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management

NCT04567407
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bilateral erector spinae blocks using ropivacaine
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Sep 3, 2026, 8:16 PM EDT