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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Rehabilitation of Speech and Language Disorders Clear all
Completed Not applicable Interventional

An Investigation of Constraint Induced Language Therapy for Aphasia

NCT00223847
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Constraint Induced Language Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 31, 2008 · Synced Jul 22, 2026, 1:48 AM EDT
Completed No phase listed Observational

Role of the Right Brain in Recovery of Language Function in Chronic Stroke

NCT00076479
View directory record Official record
Conditions
Aphasia, Cerebrovascular Accident
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments

NCT04762043
View directory record Official record
Conditions
Rehabilitation of Speech and Language Disorders, Speech Disorders, Speech, Alaryngeal, Communication Aids for Disabled, Speech Perception, Speech Intelligibility
Interventions
Experimental System: MyoVoice, Reference System: Electrolarynx
Device
Lead sponsor
Altec Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2024 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional Results available

Speech Therapy for Aphasia: Comparing Two Treatments

NCT02153710
View directory record Official record
Conditions
Stroke
Interventions
Semantic Feature Analysis therapy, Phonomotor Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Phase 1 Interventional

Assessment of Cortical Stimulation Combined With Rehabilitation to Enhance Recovery in Broca's Aphasia.

NCT00170703
View directory record Official record
Conditions
Stroke, Broca's Aphasia
Interventions
Cortical Electrical Stimulation
Device
Lead sponsor
Northstar Neuroscience
Industry
Eligibility
21 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 20, 2007 · Synced Jul 22, 2026, 1:48 AM EDT
Not listed Early Phase 1 Interventional

Efficacy of START (Startle Rehabilitation Therapy) in the Treatment Stroke-induced Aphasia/Apraxia

NCT04816799
View directory record Official record
Conditions
Stroke, Aphasia, Apraxia of Speech
Interventions
Startle Adjuvant Rehabilitation Therapy (START)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Jul 22, 2026, 1:48 AM EDT
Recruiting Phase 2Phase 3 Interventional

Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation

NCT07688551
View directory record Official record
Conditions
Aphasia, Broca's Aphasia
Interventions
tDCS
Device
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Charleston, South Carolina • Columbia, South Carolina • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 22, 2026, 1:48 AM EDT
Recruiting Phase 2 Interventional

Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)

NCT07036406
View directory record Official record
Conditions
Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired, Aphasia, Rehabilitation, Aphasia, Anomic, Aphasia, Broca, Aphasia, Conduction, Aphasia, Expressive, Aphasia Non Fluent, Aphasia, Mixed
Interventions
Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis

NCT00125242
View directory record Official record
Conditions
Aphasia, Language Disorders, Speech Disorders
Interventions
Semantic Feature Analysis (SFA)Training
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 23, 2014 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional

Intention Treatment for Anomia

NCT04267198
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Intention Treatment for Anomia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 89 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Effects of Response Elaboration Training for Aphasia

NCT00125216
View directory record Official record
Conditions
Aphasia, Language Disorders, Speech Disorders
Interventions
Response Elaboration Training
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 6, 2014 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional Results available

Effects of rTMS on Brain Activation in Aphasia

NCT03292471
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Jul 22, 2026, 1:48 AM EDT
Active, not recruiting Not applicable Interventional

Mental And Speech Developmental Delay Autism Spectrum-Type Behavioral Disorder

NCT07670000
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder, Nervous System Disorder, Neurological Disorder
Interventions
Audio fairy tales
Behavioral
Lead sponsor
Natalia Poluektova
Other
Eligibility
3 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Treating Intention In Aphasia: Neuroplastic Substrates

NCT00567242
View directory record Official record
Conditions
Aphasia, Cerebrovascular Accident
Interventions
Word-finding with intention component, Word-finding with no intention component
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 95 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 2, 2012 · Synced Jul 22, 2026, 1:48 AM EDT
Active, not recruiting Not applicable Interventional

Impact of Group Participation on Adults With Aphasia

NCT05520528
View directory record Official record
Conditions
Aphasia, Acquired, Stroke, Rehabilitation, Language Disorder, Acquired
Interventions
Language intervention with group sessions and independent tasks with emphasis on improving reading and writing skills among persons with aphasia
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Overcoming Learned Non-Use in Chronic Aphasia

NCT02012374
View directory record Official record
Conditions
Stroke-induced Aphasia
Interventions
Intensive Language Action Therapy
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
21 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Jul 22, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

Telerehabilitation for Aphasia (TERRA)

NCT04682223
View directory record Official record
Conditions
Aphasia, Stroke, Stroke Rehabilitation
Interventions
Semantically-focused therapy tasks, Phonologically-focused therapy tasks
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional

Rehabilitation and Prophylaxis of Anomia in Primary Progressive Aphasia

NCT02675270
View directory record Official record
Conditions
Aphasia, Primary Progressive, Anomia, Alzheimer Disease
Interventions
Phonological, Orthographic, Semantic, Lexical, Untrained
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
40 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Jul 22, 2026, 1:48 AM EDT
Not listed Not applicable Interventional

Predicting Rehabilitation Outcomes in Bilingual Aphasia Using Computational Modeling

NCT02916524
View directory record Official record
Conditions
Aphasia
Interventions
Semantic Feature Analysis (SFA)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
San Francisco, California • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Not applicable Interventional Results available

Treatment Intensity - Apraxia of Speech

NCT02332915
View directory record Official record
Conditions
Aphasia, CVA, Apraxia of Speech
Interventions
Sound Production Treatment (SPT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Jul 22, 2026, 1:48 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Augmenting Language Therapy for Aphasia: Levodopa

NCT01429077
View directory record Official record
Conditions
Nonfluent Aphasia, Stroke
Interventions
levodopa/carbidopa, Placebo comparator
Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 24, 2013 · Synced Jul 22, 2026, 1:48 AM EDT