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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Relation, Mother-Child Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation Study of the Impact of the New Brain Builders Parenting Class

NCT03866616
View directory record Official record
Conditions
Child Development, Mother-Child Interaction
Interventions
Brain Builders Parenting Class, Control (Usual care)
Behavioral
Lead sponsor
William Marsh Rice University
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Phase 2 Interventional

Relational Parenting Group for Opioid-addicted Mothers

NCT00319241
View directory record Official record
Conditions
Substance Abuse, Child Abuse
Interventions
Parenting Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Jul 21, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent Encouragement And Coaching of Happiness in Youth

NCT06725160
View directory record Official record
Conditions
Depression, Parent-Child Relations
Interventions
Parent Coaching, Active Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
4 Years to 99 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jul 21, 2026, 11:28 AM EDT
Not listed Not applicable Interventional

A Scaleable Video Coaching Intervention for Opioid-using Mothers

NCT04749771
View directory record Official record
Conditions
Child Behavior, Parent-Child Relations, Substance Use, Substance Abuse
Interventions
Filming Interactions to Nurture Development, The Healthy Toddler Program
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Up to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Jul 21, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional

Postpartum Intervention for Mothers With Opioid Use Disorders (R33)

NCT07632053
View directory record Official record
Conditions
Opioid Use Disorder, Parent-Child Relations
Interventions
Mom Power
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep-Safe: A Strong African American Families Study

NCT03505203
View directory record Official record
Conditions
Weight Gain
Interventions
Sleep Soothe, Sleep Safe
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
17 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Jul 21, 2026, 11:28 AM EDT
Completed No phase listed Observational

Expanding Knowledge About and Evaluating Services for Incarcerated Pregnant and Postpartum Women in Arkansas

NCT04421235
View directory record Official record
Conditions
Health Problems in Pregnancy, Childbirth Problems, Maternal Care Patterns, Quality of Life, Emotional Stress, Health Care Acceptability, Health Risk Behaviors, Parent-Child Relations
Interventions
Childbirth support
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)

NCT04100577
View directory record Official record
Conditions
Infant Mortality, Infant Death, Racial Bias, Prenatal Stress, Prenatal Care, Maternal Child Health, Health Problems in Pregnancy, Adverse Childhood Experiences, Mental Health, Support Groups, Minority Health, Healthcare Disparities, Maternal-child Health Services, Social Determinants of Health, Trust, Physician-Patient Relations, Quality of Care
Interventions
Today Not Tomorrrow Pregnancy and Infant Support Program
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months

NCT03334266
View directory record Official record
Conditions
Obesity, Infant Obesity, Mother-Child Relations, Dietary Habits, Breast Feeding, Physical Activity, Childhood Obesity, Feeding Behavior
Interventions
Family Spirit Nurture (FSN), Injury Prevention Education (IPE), Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years to 24 Years · Female only
Enrollment
259 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
3
States / cities
Fort Defiance, Arizona • Whiteriver, Arizona • Shiprock, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Jul 21, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent-Child Memory Study: Improving Future Thinking Among Mothers

NCT06145919
View directory record Official record
Conditions
Behavior, Health
Interventions
Episodic Future Thinking (EFT), Episodic Recent Thinking (ERT)
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
5 Years and older · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Jul 21, 2026, 11:28 AM EDT
Withdrawn Not applicable Interventional

Project BELONG: Breaking the Cycle of Intergenerational Family Violence and Trauma

NCT03212339
View directory record Official record
Conditions
Mother-child Relations, Parenting, Parent Child Abuse, Family Conflict, Parental Stress, Family Relations, Childhood Disorder of Social Functioning, Unspecified
Interventions
Therapeutic intervention
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2019 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Piloting a Precision Approach to Home Visiting

NCT03975530
View directory record Official record
Conditions
Parenting, Mother-Child Relations, Child Development
Interventions
Precision Family Spirit, Standard Family Spirit
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Sault Ste. Marie, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional

Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers

NCT01240993
View directory record Official record
Conditions
Parenting Capacities of Substance Abusing Mothers
Interventions
Mothers and Toddlers Program, Parent Education
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes

NCT05229146
View directory record Official record
Conditions
Behavioral Health
Interventions
Episodic Future Thinking
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Children's Learning Centers Group FNI

NCT03908268
View directory record Official record
Conditions
Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem, Development Delay
Interventions
Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
24 Months to 57 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cos Cob, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers

NCT00319436
View directory record Official record
Conditions
Maternal Substance Use, Child Abuse and Neglect
Interventions
Mentalizing Therapy for Substance Using Mothers, Standard Parent Education for Substance Using Mothers
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2020 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Collaborative Perinatal Mental Health and Parenting Support in Primary Care

NCT02724774
View directory record Official record
Conditions
Parenting, Mother-child Relations
Interventions
Promoting First Relationships®
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity

NCT04818112
View directory record Official record
Conditions
Parent-Child Relations, Maternal Behavior, Infant Behavior
Interventions
ATVV, Attention control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mother-infant Bonding During COVID-19

NCT04531618
View directory record Official record
Conditions
Child Development, Mother-Infant Interaction, Relation, Parent-Child
Interventions
Emotional Exchange (EE), Newborn Care (NC)
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
12 Hours to 72 Hours
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions for Depressed Low Income Mothers and Their Infants

NCT00105573
View directory record Official record
Conditions
Depression
Interventions
Maternal interpersonal psychotherapy (IP), Infant-parent psychotherapy, Informational meetings plus treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Promoting Self-Management of Breast and Nipple Pain With Technology (PROMPT) for Breastfeeding Women Study

NCT05262920
View directory record Official record
Conditions
Breastfeeding, Exclusive, Pain, Acute, Maternal Distress, Parent-Child Relations, Self Efficacy
Interventions
The BSM Intervention, Attention Control
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Farmington, Connecticut • Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jul 21, 2026, 11:28 AM EDT
Recruiting Not applicable Interventional

Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children

NCT06262178
View directory record Official record
Conditions
PTSD, Depression, Parent-Child Relations
Interventions
Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
El Paso, Texas • Killeen, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Results available

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms

NCT04045132
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations
Interventions
Social Media-Based Parenting Program, MoodGym
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Jul 21, 2026, 11:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Norwalk Feasibility Study

NCT04048720
View directory record Official record
Conditions
Behavior Problem, Development Delay, Emotional Disturbances, Family Conflict, Relation, Mother-Child
Interventions
Family Nurture Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
24 Months to 78 Months
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Norwalk, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 8, 2020 · Synced Jul 21, 2026, 11:28 AM EDT