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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:48 PM EST

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Showing 25–48 of 463 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Renal Failure, Acute Clear all
Completed No phase listed Observational

Timing of Coronary Angiography, Cardiac Surgery, and Adverse Renal and Cardiac Events (MARCE)

NCT02332070
View directory record Official record
Conditions
Acute Kidney Injury, Renal Insufficiency
Interventions
cardiac surgery
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
Not listed
Enrollment
965 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Nov 15, 2026, 5:48 PM EST
Completed Not applicable Interventional Results available

Drug-Targeted Alerts for Acute Kidney Injury

NCT02771977
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Drug-specific alert
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
5,060 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Nov 15, 2026, 5:48 PM EST
Completed Not applicable Interventional

Ischemic Preconditioning to Prevent Acute Kidney Injury

NCT02167152
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Ischemic preconditionin
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Nov 15, 2026, 5:48 PM EST
Completed Phase 2 Interventional

Deferiprone for the Prevention of Contrast-Induced Acute Kidney Injury

NCT01146925
View directory record Official record
Conditions
Contrast-Induced Acute Kidney Injury
Interventions
CRMD-001-Deferiprone, Placebo
Drug
Lead sponsor
CorMedix Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
8
States / cities
Indianapolis, Indiana • Detroit, Michigan • Petoskey, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 27, 2011 · Synced Nov 15, 2026, 5:48 PM EST
Terminated Phase 2 Interventional Results available

Safety & Efficacy of BCT197 in Patients Undergoing Cardiac Surgery

NCT01336959
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
BCT197 Part A, Placebo, BCT197 Part B
Drug
Lead sponsor
Mereo BioPharma
Industry
Eligibility
18 Years to 85 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Orange, California • Saginaw, Michigan • Lincoln, Nebraska + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2020 · Synced Nov 15, 2026, 5:48 PM EST
Completed Not applicable Interventional

Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass

NCT01228305
View directory record Official record
Conditions
Congenital Heart Disease, Cardiopulmonary Bypass
Interventions
Acetaminophen
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
1 Day to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Nov 15, 2026, 5:48 PM EST
Completed No phase listed Observational Results available

NIRS Monitoring to Detect AKI in Preterm Infants

NCT03384173
View directory record Official record
Conditions
Acute Kidney Injury, Premature Infant
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
1 Minute to 7 Days
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Nov 15, 2026, 5:48 PM EST
Active, not recruiting Not applicable Interventional

CTSN Embolic Protection Trial

NCT06027788
View directory record Official record
Conditions
Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease
Interventions
CardioGard Embolic Protection Cannula, Standard Aortic Cannula
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years and older
Enrollment
842 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
20
States / cities
North Little Rock, Arkansas • Los Angeles, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Nov 15, 2026, 5:48 PM EST
Not listed No phase listed Observational Accepts healthy volunteers

Postoperative Respiratory Abnormalities

NCT04079829
View directory record Official record
Conditions
Respiratory Failure, Respiratory Arrest, Respiratory Distress Syndrome, Acute Respiratory Failure, Acute Respiratory Failure With Hypoxia, Acute Respiratory Failure With Hypercapnia, Acute Respiratory Failure Post Surgical, Acute Respiratory Failure Postprocedural, Acute Respiratory Failure Following Trauma and Surgery, Acute Respiratory Failure Requiring Reintubation, Acute Respiratory Failure Post Traumatic, Acute Respiratory Decompensation, Shock, Shock, Septic, Shock, Cardiogenic, Acute Cardiac Failure, Multi Organ Failure, Acute Kidney Failure
Interventions
Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data
Other
Lead sponsor
Efficacy Care R&D Ltd
Industry
Eligibility
18 Years to 90 Years
Enrollment
50,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Nov 15, 2026, 5:48 PM EST
Terminated Not applicable Interventional Results available

Immunomodulatory Biomimetic Device to Treat Myocardial Stunning in End-stage Renal Disease Patients

NCT03539861
View directory record Official record
Conditions
End Stage Renal Disease, Acute Kidney Injury, Chronic Kidney Disease Stage 5
Interventions
Hemodialysis
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Nov 15, 2026, 5:48 PM EST
Active, not recruiting Phase 4 Interventional Results available

Ketamine and Kidney Injury in Cardiac Surgery

NCT05268562
View directory record Official record
Conditions
Cardiac Surgery
Interventions
Ketamine, Propofol
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Nov 15, 2026, 5:48 PM EST
Active, not recruiting No phase listed Observational

Cardiopulmonary Bypass Induced Red Blood Cell Lysis

NCT05189262
View directory record Official record
Conditions
Cardiopulmonary Bypass, Cardiac Surgery, Kidney Injury, Acute
Interventions
Blood and urine collection
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Nov 15, 2026, 5:48 PM EST
Recruiting Phase 1 Interventional

Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention

NCT07084129
View directory record Official record
Conditions
Sepsis
Interventions
personalized dosing adjustment of vancomycin
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Month to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Nov 15, 2026, 5:48 PM EST
Terminated No phase listed Observational Accepts healthy volunteers

Search for New Methods to Detect Acute Renal Failure

NCT00026702
View directory record Official record
Conditions
Kidney Disease, Kidney Failure, Kidney Failure, Chronic, Healthy Volunteers, Renal Tubular Toxicity
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
3 Years and older
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Nov 15, 2026, 5:48 PM EST
Withdrawn Phase 2 Interventional

Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Trauma Patients

NCT04531579
View directory record Official record
Conditions
Acute Kidney Injury, Ischemia Reperfusion Injury
Interventions
Valproic Acid Solution, Isotonic saline solution
Drug
Lead sponsor
Westat
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Baltimore, Maryland • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 29, 2021 · Synced Nov 15, 2026, 5:48 PM EST
Completed No phase listed Observational

Mehran 2.0 Risk Score for Prediction of CA-AKI After PCI

NCT05132062
View directory record Official record
Conditions
Contrast-induced Nephropathy
Interventions
Percutaneous Coronary Intervention
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
14,616 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 24, 2021 · Synced Nov 15, 2026, 5:48 PM EST
Active, not recruiting Not applicable Interventional Results available

Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure

NCT04334668
View directory record Official record
Conditions
Volume Overload
Interventions
Oral Sodium Chloride, Placebo
Dietary Supplement · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Nov 15, 2026, 5:48 PM EST
Completed No phase listed Observational

Nova Max Creatinine and eGFR Meter System

NCT05118074
View directory record Official record
Conditions
Chronic Kidney Diseases, Acute Kidney Injury
Interventions
Creatinine, eGFR
Diagnostic Test
Lead sponsor
Nova Biomedical
Industry
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Medley, Florida • Miami Gardens, Florida • Miami Lakes, Florida
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Nov 15, 2026, 5:48 PM EST
Completed No phase listed Observational

The Drug Induced Renal Injury Consortium

NCT02159209
View directory record Official record
Conditions
Acute Kidney Injury, Adverse Drug Reaction, Acute Kidney Failure, Kidney Failure, Kidney Disease
Interventions
Not listed
Lead sponsor
Ravindra Mehta
Other
Eligibility
2 Years and older
Enrollment
634 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
8
States / cities
Birmingham, Alabama • San Diego, California • Aurora, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2016 · Synced Nov 15, 2026, 5:48 PM EST
Not listed Phase 3 Interventional

Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney

NCT02474667
View directory record Official record
Conditions
Delayed Graft Function
Interventions
ANG-3777, Placebo
Drug · Other
Lead sponsor
Angion Biomedica Corp
Industry
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
30
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Nov 15, 2026, 5:48 PM EST
Withdrawn Phase 4 Interventional

Combination Diuretic Therapy for Acute Decompensated Heart Failure

NCT05840536
View directory record Official record
Conditions
Acute Decompensated Heart Failure
Interventions
Furosemide plus Chlorothiazide, Furosemide
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Nov 15, 2026, 5:48 PM EST
Completed No phase listed Observational

Long Term Cognitive Impact of Pediatric Acute Renal Injury

NCT02372734
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Pediatric Quality of Life (Peds QL) Survey
Other
Lead sponsor
University of Florida
Other
Eligibility
2 Years to 36 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Nov 15, 2026, 5:48 PM EST
Completed Not applicable Interventional Results available

Achieving Medication Safety During Acute Kidney Injury

NCT01134900
View directory record Official record
Conditions
Kidney Failure, Acute
Interventions
Pharmacy Dashboard Review and Intervention
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 27, 2012 · Synced Nov 15, 2026, 5:48 PM EST
Completed No phase listed Observational

VIDAS Nephroclear (NCL) CCL14 - Sample Stability

NCT05271617
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
VIDAS® NEPHROCLEAR™ CCL14
Diagnostic Test
Lead sponsor
BioMérieux
Industry
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2023 · Synced Nov 15, 2026, 5:48 PM EST