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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:05 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 449 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Renal Insufficiency, Acute Clear all

Conditions: End-stage Renal Disease, Malnutrition; Protein
Interventions: Intradialytic Parenteral Nutrition; Other
Lead sponsor: Patient Care America; Industry
Eligibility: 18 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Pompano Beach, Florida

Conditions: Acute Kidney Injury, Chronic Kidney Disease, Hypertension
Interventions: Iodohippurate, 24 hour ambulatory Blood Pressure, Peripheral Arterial Tonometry, Pulse Wave Velocity, Gadolinium; Drug · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 7 Years to 17 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Hepatorenal Syndrome, Acute Kidney Injury
Interventions: R2R01, Terlipressin; Drug
Lead sponsor: River 2 Renal Corp.; Industry
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 7
States / cities: San Francisco, California • Atlanta, Georgia • Boston, Massachusetts + 4 more

Conditions: Cardiac Surgical Procedures
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Acute Kidney Injury
Interventions: Basis, Placebo; Dietary Supplement
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Kidney Injury, Acute Kidney Injury Due to Sepsis
Interventions: QUELIMMUNE (SCD-PED); Device
Lead sponsor: SeaStar Medical; Industry
Eligibility: Up to 22 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 15
States / cities: Birmingham, Alabama • Palo Alto, California • San Francisco, California + 11 more

Conditions: AKI, CHD - Congenital Heart Disease, Surgery
Interventions: Nitric Oxide, Oxygen; Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 1 Day to 31 Days
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Acute Kidney Injury
Interventions: Oral niacinamide, 1 gram daily, Oral niacinamide, 3 gram daily, Placebo; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Renal Failure
Interventions: Ultrasound for measurement of Inferior Vena Cava size.; Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Acute Kidney Injury
Interventions: Early RASi restart strategy, Usual Care; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute, Myocarditis Due to Drug, Myocarditis Viral, Pericardial Diseases, Valvular Heart Diseases, Hypertension, Sepsis, Acute Kidney Injury, Pulmonary Edema - Acute, Pulmonary Edema With Heart Failure, Pulmonary Edemas, Acute Respiratory Distress Syndrome, Pulmonary Embolism Acute, Pulmonary Embolism (Diagnosis), Pulmonary Embolism Acute Massive, Pulmonary Embolism Subacute Massive, Venous Thrombosis Pulmonary, Venous Thrombosis (Disorder), Venous Thrombosis, Deep, Peripheral Arterial Disease, Peripheral Arterial Disease (PAD), Aortic Diseases, Muskuloskeletal Diseases, Brain Aging, Brain Aneurysm, Brain Aging Related Conditions, Ultrasound, Ultrasound Exams, Ultrasound Guidance
Interventions: OMNIPHYS Multimodal Ultrasound Imaging System; Device
Lead sponsor: Truway Health, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 25,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2046
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Kidney Injury in Pediatric Patients
Interventions: Prismaflex HF20 CRRT Filter, Prismaflex® System 7.10 and 7.20; Device
Lead sponsor: Vantive Health LLC; Industry
Eligibility: Not listed
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 6
States / cities: Stanford, California • Iowa City, Iowa • Grand Rapids, Michigan + 3 more

Conditions: Acute Kidney Injury
Interventions: Urine collection for NEPHROCLEAR CCL14 Test; Diagnostic Test
Lead sponsor: Astute Medical, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Kidney Failures, Acute
Interventions: Intra-Renal Fenoldopam, Furosemide; Drug
Lead sponsor: Southeast Renal Research Institute; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Acute Kidney Injury
Interventions: SGLT2 inhibitor; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 40 Years to 75 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Infection, Acute Kidney Injury, Sepsis
Interventions: Piperacillin + Tazobactam, meropenem; Drug
Lead sponsor: Bassett Healthcare; Other
Eligibility: 18 Years and older
Enrollment: 852 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 7
States / cities: Worcester, Massachusetts • Omaha, Nebraska • Cooperstown, New York + 4 more

Conditions: Renal Failure
Interventions: LCP-Tacro, Prograf; Drug
Lead sponsor: Asahi Kasei Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 326 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: San Diego, California

Conditions: Acute Kidney Injury, Post-Operative Delirium, Icu Delirium, Acute Renal Failure, Delirium
Interventions: atorvastatin, placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 653 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Acute Kidney Injury (Nontraumatic)
Interventions: CXA-10 emulsion, Placebo; Drug
Lead sponsor: Complexa, Inc.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Kalamazoo, Michigan

Conditions: Systemic Inflammatory Response Syndrome, Acute Kidney Injury
Interventions: coronary artery bypass grafting using cardiopulmonary bypass; Procedure
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Acute Kidney Injury, Acute Interstitial Nephritis, Kidney Diseases
Interventions: Not listed
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2035
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Cardiac Surgery
Interventions: MIB-626, Placebo; Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Kidney Injury, Renal Insufficiency
Interventions: cardiac surgery; Procedure
Lead sponsor: Baylor Research Institute; Other
Eligibility: Not listed
Enrollment: 965 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Acute Kidney Injury
Interventions: Drug-specific alert; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 5,060 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

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Impact of IDPN on Nutrition Markers in Patients Receiving ICHD

Severe Sepsis in Children - IMPRESS-C

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

Diagnostic Accuracy of Doppler Resistive Indices for Early Diagnosis of Acute Kidney Injury .

Pharmacokinetics, Pharmacodynamics and Safety of Basis in Acute Kidney Injury Study

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

NO During CPB in Neonates to Reduce Risk of AKI

Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury

Inferior Vena Cava (IVC) Size in Acute Renal Failure

A Prompt REstart Study of Renin-Angiotensin System Inhibitors After Acute Kidney Injury

Multimodal Physiologic State Intelligence Study

Prismaflex HF20 Set and Prismaflex® System 7.10/7.20 for Acute Continuous Renal Replacement Therapy (CRRT) in Children

A Sample Collection Study to Validate the NEPHROCLEAR™ CCL14 Test

Intra-Renal Therapy of Diuretic Unresponsive Acute Kidney Injury

SGLT2 Inhibitors After Acute Kidney Injury With Indications Pilot

The Vancomycin Piperacillin/Tazobactam (VPT) Patient Safety Trial (VPS)

Safety and Efficacy of LCP-Tacro™ Once Daily in Stable Renal Transplant Patients Converted From Prograf® Twice Daily

Short-term Atorvastatin's Effect on Acute Kidney Injury Following Cardiac Surgery

Study of CXA-10 in Healthy Volunteers

Platelets as Regulators of Inflammation in Cardiac Surgery

Biorepository to Support Research in Kidney Diseases

Nicotinamide Mononucleotide in Patients Undergoing Cardiac Surgery

Timing of Coronary Angiography, Cardiac Surgery, and Adverse Renal and Cardiac Events (MARCE)

Drug-Targeted Alerts for Acute Kidney Injury