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ClinicalTrials.gov public records Last synced Sep 9, 2026, 11:39 PM EDT

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Showing 1–24 of 203 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Replacement, Hip Clear all
Terminated Phase 3 Interventional Results available

A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hip Replacement Surgery Compared With Oxycodone and Placebo Followed by a Voluntary Open-Label Extension For Safety

NCT00364533
View directory record Official record
Conditions
Arthroplasty
Interventions
Tapentadol IR (CG5503), Placebo, Oxycodone HCL IR
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years to 80 Years
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
45
States / cities
Birmingham, Alabama • Mobile, Alabama • Sheffield, Alabama + 42 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Phase 3 Interventional

Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003

NCT02289716
View directory record Official record
Conditions
Osteoarthritis, Pain
Interventions
Placebo, Fulranumab 1 mg, Fulranumab 3 mg
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
7
States / cities
El Cajon, California • Sherman Oaks, California • Miami, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Phase 4 Interventional Results available

PO vs. IV Acetaminophen Given Perioperatively for 24 hr Post-op Pain Control Following Total Hip or Knee Replacement

NCT02244619
View directory record Official record
Conditions
Post-op Pain
Interventions
Oral acetaminophen, IV acetaminophen
Drug
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years and older
Enrollment
515 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kettering, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional

Increasing Awareness of Opioid Disposal in the Orthopedic Patient Population

NCT03954964
View directory record Official record
Conditions
Knee Total Joint Replacement, Hip Total Joint Replacement
Interventions
Education on disposal of opioids
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Phase 3 Interventional

Rivaroxaban (10mg) Given Once Daily in Patients Undergoing Total Hip Replacement Compared to Enoxaparin

NCT00329628
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
Rivaroxaban (BAY59-7939), Enoxaparin
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
4,541 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
13
States / cities
Birmingham, Alabama • Northport, Alabama • Phoenix, Arizona + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2014 · Synced Sep 9, 2026, 11:39 PM EDT
Not listed Not applicable Interventional

Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications

NCT04229368
View directory record Official record
Conditions
Hip Arthropathy, Knee Arthropathy, Vitamin D Deficiency
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Sep 9, 2026, 11:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Radlink GPS Provide a Valid Intra-operative Assessment of Acetabular Inclination and Anteversion

NCT02808169
View directory record Official record
Conditions
Implant Position in Total Hip Replacement
Interventions
Not listed
Lead sponsor
Barrett, William, M.D.
Individual
Eligibility
20 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Renton, Washington
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 9, 2026, 11:39 PM EDT
Recruiting Not applicable Interventional

Binaural Beats for Postoperative Pain and Anxiety Reduction

NCT07437469
View directory record Official record
Conditions
TKA, THA, Anxiety, Binaural Beats, Music Exposure, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Total Knee Replacement, Total Hip Replacement
Interventions
Binaural Beats Audio Intervention, Music of Choice
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional Results available

Improvement of Patient Satisfaction and Overall Outcomes Using HealthLoop

NCT03481595
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Interventions
HealthLoop mobile application
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Sep 9, 2026, 11:39 PM EDT
Active, not recruiting Not applicable Interventional

Trident II Tritanium Acetabular Shell Outcomes Study

NCT02999009
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
Trident II Tritanium Acetabular Shell
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years to 80 Years
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2031
U.S. locations
9
States / cities
Tucson, Arizona • Jacksonville, Florida • Des Plaines, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 9, 2026, 11:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Continuous Postoperative Pulse Oximetry in Patients Presenting for Total Hip and Total Knee Replacement

NCT01189565
View directory record Official record
Conditions
Total Knee Replacement
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
19 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2013 · Synced Sep 9, 2026, 11:39 PM EDT
Not listed No phase listed Observational

CGM Monitoring in T2DM Patients Undergoing Orthopaedic Replacement Surgery

NCT05666479
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Interventions
Dexcom G6 Pro Continuous Glucose Monitor (CGM)
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional

Pain After Preoperative UltraSound Guided Hip Injections for Total Hip Arthroplasty (PUSH)

NCT04219098
View directory record Official record
Conditions
Total Hip Replacement, Arthroplasty
Interventions
Butterfly IQ, Standard of Care
Procedure · Other
Lead sponsor
Anne Arundel Health System Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Annapolis, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional Results available

Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)

NCT00358735
View directory record Official record
Conditions
Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE), Bleeding
Interventions
ActiveCare CECT device, Enoxaparin
Device · Drug
Lead sponsor
Medical Compression Systems
Industry
Eligibility
18 Years and older
Enrollment
411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
9
States / cities
La Jolla, California • Loma Linda, California • Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional Results available

A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform

NCT03737149
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
mymobility with Apple Watch
Other
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
6,559 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
26
States / cities
Fremont, California • Irvine, California • Redwood City, California + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional Results available

Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty

NCT03016078
View directory record Official record
Conditions
Arthroplasties, Hip Replacement, Arthroplasties, Knee Replacement
Interventions
Mepilex Border Post-Op Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Gilbert, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Sep 9, 2026, 11:39 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Suzetrigine in Total Hip Arthroplasty

NCT07226700
View directory record Official record
Conditions
Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\), Total Hip Replacement, Total Hip Replacement Surgery, Total Hip Replacements, Total Hip Replacement Arthroplasty, Suzetrigine, Pain Management, Pain, Nav 1.8, JOURNAVX, Opioid Cessation, Opioid Consumption, Postoperative, Multimodal Analgesia, Randomized Controlled Trial, Randomized Controlled Study, Randomized Controlled Trials
Interventions
Suzetrigine, Placebo
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 9, 2026, 11:39 PM EDT
Completed No phase listed Observational

Ceramic On Ceramic (COC) 36mm PAS IDE Rollover Subjects; Ceramic Acetabular Bearing With Ceramic Femoral Head in Total Hip Replacement

NCT02096198
View directory record Official record
Conditions
Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-Traumatic Osteoarthritis of Hip
Interventions
Not listed
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
20 Years to 75 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
5
States / cities
Sacramento, California • Denver, Colorado • Winston-Salem, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2019 · Synced Sep 9, 2026, 11:39 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Hip DAA Closure Techniques

NCT06006572
View directory record Official record
Conditions
Total Hip Replacement, Wound Complication
Interventions
wound closure subcuticular running stitch using 3-0 monocryl suture without skin adhesive, wound closure subcuticular running stitch using 3-0 monocryl suture with two layers of skin adhesive
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional Results available

Improvement of Patient Satisfaction and Clinical Outcomes Using JointCOACH

NCT03499028
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Interventions
JointCOACH
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
446 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional Results available

Accolade® TMZF® Hip Stem Outcomes Study

NCT00957658
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
Accolade® TMZF® Hip Stem
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years to 90 Years
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
11
States / cities
Newport Beach, California • San Diego, California • Boynton Beach, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2017 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Phase 3 Interventional Results available

Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee Replacement

NCT01094886
View directory record Official record
Conditions
Arthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Thromboembolism
Interventions
Rivaroxaban
Drug
Lead sponsor
Ortho-McNeil Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
5
States / cities
Denver, Colorado • Hollywood, Florida • Tamarac, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Phase 4 Interventional

Effect of Prophylactic Antibiotics on Intra-Operative Culture Results

NCT01174212
View directory record Official record
Conditions
Infection, Arthroplasty
Interventions
Prophylactic Antibiotics, Control Antibiotics
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2012 · Synced Sep 9, 2026, 11:39 PM EDT
Completed Not applicable Interventional

Fish Oil in Total Hip Replacement Randomized Clinical Trial

NCT04360239
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Fish Oil
Dietary Supplement
Lead sponsor
Jeffrey L Stimac MD
Other
Eligibility
18 Years to 99 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced Sep 9, 2026, 11:39 PM EDT