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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Reproductive Sterilization Clear all
Active, not recruiting Not applicable Interventional

Operating Room Air Filtration/Sterilization

NCT04610294
View directory record Official record
Conditions
Surgery
Interventions
Functioning Aerus air filtration/sterilization, Deactivated Aerus air filtration/sterilization
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
66,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 22, 2026, 2:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Real World Effectiveness and Safety of Hysteroscopic (Essure®) Compared to Laparoscopic Sterilization

NCT03438682
View directory record Official record
Conditions
Sterility, Female, Contraception, Contraceptive Device; Complications
Interventions
Essure, Laparoscopic sterilization, Intrauterine Device (IUD)
Device · Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
89,203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

VAS-2 Vasectomy With the Vax-X

NCT00663533
View directory record Official record
Conditions
Healthy
Interventions
Vas-X
Device
Lead sponsor
University of Washington
Other
Eligibility
30 Years to 55 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide for Pain Management During In-office Transcervical Sterilization

NCT02312739
View directory record Official record
Conditions
Contraception, Inhalation of Nitrous Oxide
Interventions
In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac, Placebo pills, Oxygen, Nitrous Oxide
Procedure · Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 5, 2016 · Synced Jul 22, 2026, 2:10 PM EDT
Completed No phase listed Observational

Proportion of Hysterectomy After Female Sterilization

NCT02532361
View directory record Official record
Conditions
Hysterectomy
Interventions
Hysteroscopic device placement including Essure (ESS305, BAY1454032), Tubal ligation
Device · Procedure
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 49 Years · Female only
Enrollment
10,578 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
New Jersey, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 22, 2016 · Synced Jul 22, 2026, 2:10 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers Results available

Adiana Post-Approval Clinical Study (APACS)

NCT01177670
View directory record Official record
Conditions
Women Contraception
Interventions
Not listed
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
9
States / cities
Elk Grove, California • Arlington Heights, Illinois • Columbia, Missouri + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2012 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Not applicable Interventional Results available

Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery

NCT03135431
View directory record Official record
Conditions
Contraception
Interventions
Bilateral Salpingectomy, Bilateral Tubal Ligation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Standard Tubal Ligation Versus Salpingectomy for Sterilization at the Time of Cesarean Delivery

NCT03028623
View directory record Official record
Conditions
Method of Tubal Ligation at the Time of Cesarean Section
Interventions
Salpingectomy, Tubal ligation
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
21 Years and older · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Jul 22, 2026, 2:10 PM EDT
Completed No phase listed Observational

Characterization of the Essure System Tubal Sterilization Using Ultrasound and X-Ray

NCT00588497
View directory record Official record
Conditions
Tubal Sterilization
Interventions
Micro-insert hysteroscopic sterilization, Plain abdominal Xray, Pelvic Ultrasound, Hysterosalpingogram
Procedure · Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 22, 2011 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Intrauterine Lidocaine Infusion for Essure Sterilization Procedures

NCT00613834
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Sterile Saline
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Jul 22, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Prospective Multi-Center Trial for FemBloc Permanent Birth Control

NCT05977751
View directory record Official record
Conditions
Contraception
Interventions
FemBloc
Device
Lead sponsor
Femasys Inc.
Industry
Eligibility
21 Years to 50 Years · Female only
Enrollment
573 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2031
U.S. locations
8
States / cities
Chandler, Arizona • Palo Alto, California • Sacramento, California + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Jul 22, 2026, 2:10 PM EDT
Completed No phase listed Observational Results available

A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation Test

NCT01740687
View directory record Official record
Conditions
Contraception, Menorrhagia
Interventions
ESS305 (Essure, BAY1454032), NovaSure
Device · Procedure
Lead sponsor
Bayer
Industry
Eligibility
21 Years to 50 Years · Female only
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
17
States / cities
Aurora, Colorado • Ocala, Florida • Decatur, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Jul 22, 2026, 2:10 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety & Efficacy Study of the Adiana System for Women Who Desire Permanent Birth Control (Sterilization)

NCT00737061
View directory record Official record
Conditions
Reproductive Sterilization
Interventions
Adiana Transcervical Sterilization System
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
770 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2013
U.S. locations
14
States / cities
Phoenix, Arizona • Roseville, California • San Rafael, California + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2017 · Synced Jul 22, 2026, 2:10 PM EDT
Terminated Not applicable Interventional Results available

Can SIS Using Air Bubbles Replace HSG for Fallopian Tubal Patency After Essure Placement

NCT02628873
View directory record Official record
Conditions
Contraception
Interventions
HyCoSy
Device
Lead sponsor
Wright State University
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Jul 22, 2026, 2:10 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Effectiveness Study of Zymar Versus Vigamox for Preoperative Sterilization of the Ocular Surface After Loading Dose

NCT00347828
View directory record Official record
Conditions
Eye Infection, Infection
Interventions
Moxifloxacin ophthalmic solution 0.5%, Gatifloxacin ophthalmic solution 0.3%
Drug
Lead sponsor
Ophthalmic Consultants of Boston
Other
Eligibility
25 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 3, 2006 · Synced Jul 22, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Patient-centered Information on Permanent Contraception

NCT06296797
View directory record Official record
Conditions
Contraception, Reproductive Behavior, Contraception Behavior
Interventions
Control arm: Existing educational website, Advancing Access Website
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Prophylaxis Prior to Cataract Surgery Conjunctival Flora and Optimal Ocular Sterilization Technique Prior to Cataract Surgery

NCT00406913
View directory record Official record
Conditions
Endophthalmitis, Cataract Surgery, Prophylaxis
Interventions
mupirocin ointment, SOC sterilization
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cohort Study of Risk Reducing Salpingectomy

NCT02165709
View directory record Official record
Conditions
Sterilization, Tubal, Salpingectomy, Ovary, Prevention & Control
Interventions
Salpingectomy, Traditional sterilization
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 60 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Jul 22, 2026, 2:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Development of an Intrauterine Pressure Threshold to Confirm Tubal Occlusion

NCT04071392
View directory record Official record
Conditions
Sterilization, Female, Fallopian Tube Occlusion
Interventions
Hysterosalpingogram (HSG)
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 9, 2019 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Phase 3 Interventional

Impact of Sterilization Technique on Incidence of Urinary Tract Infection After Cystoscopy

NCT00177112
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
clean patient preparation for cystoscopy, sterile patient preparation for cystoscopy
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2008 · Synced Jul 22, 2026, 2:10 PM EDT
Recruiting No phase listed Observational

Comparison of Two Salpingectomy Techniques for Sterilization at the Time of Cesarean Delivery

NCT06273683
View directory record Official record
Conditions
Permanent Sterilization, Pregnancy Related
Interventions
Hand-held bipolar energy instrument, Traditional suture ligation
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
21 Years and older · Female only
Enrollment
900 participants
Timeline
2024 – 2027
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 22, 2026, 2:10 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

NCT05688943
View directory record Official record
Conditions
Anesthesia, Tubal Ligation
Interventions
Spinal Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 22, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Patient-centered Outcomes After Permanent Female Sterilization Procedure(POPS Trial)

NCT05518175
View directory record Official record
Conditions
Sterility, Female
Interventions
Traditional laparoscopy, Single site laparoscopy, V-Notes surgery
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jul 22, 2026, 2:10 PM EDT