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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Rhinoplasty Clear all
Completed Phase 4 Interventional Results available

Narcotics vs NSAIDs for Post-operative Analgesia in Outpatient Rhinoplasty

NCT03457116
View directory record Official record
Conditions
Rhinoplasty, Non-steroidal Ant Inflammatory Drugs, Opioid Use
Interventions
Norco, NSAID
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Allograft Cartilage in Cosmetic and Reconstructive Rhinoplasty

NCT05566808
View directory record Official record
Conditions
Rhinoplasty
Interventions
Autologous Costal Cartilage Graft, Costal Cartilage Allograft.
Other
Lead sponsor
Musculoskeletal Transplant Foundation
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Jun 26, 2026, 2:08 AM EDT
Completed No phase listed Observational

Rhinoplasty Scar Comparison

NCT03748459
View directory record Official record
Conditions
Surgical Incision, Nose Deformity
Interventions
Closure with Permanent Suture, Closure with Resorbable Suture
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty

NCT01225250
View directory record Official record
Conditions
Rhinoplasty
Interventions
Polydioxanone (PDS) plates, Caudal septal extension graft performed through endonasal rhinoplasty
Device · Procedure
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty

NCT04169308
View directory record Official record
Conditions
Deformity of Nasal Cartilage
Interventions
Restylane-L® Filler injection
Drug
Lead sponsor
DeNova Research
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Jun 26, 2026, 2:08 AM EDT
Withdrawn Not applicable Interventional

Arnica Montana and Bromelain in Rhinoplasty

NCT03586232
View directory record Official record
Conditions
Wound Healing
Interventions
Arnica Montana, Bromelain, Placebo
Dietary Supplement · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Jun 26, 2026, 2:08 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis

NCT05774717
View directory record Official record
Conditions
Surgery, Postoperative Blood Loss
Interventions
Tranexamic acid
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jun 26, 2026, 2:08 AM EDT
Withdrawn Not applicable Interventional

Effects of Mindfulness Meditation on Rhinoplasty Outcomes

NCT03727815
View directory record Official record
Conditions
Nose Deformity
Interventions
Mindfulness Pain Management Arm, Mindfulness Self Esteem Arm
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Baltimore, Maryland • Lutherville-Timonium, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Jun 26, 2026, 2:08 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Preoperative Nerve Block for Rhinoplasty/Septoplasty

NCT03780478
View directory record Official record
Conditions
Nasal Fracture, Deviated Nasal Septum
Interventions
Nerve block, Placebo Saline Injection
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Utility of Long-acting Local Anesthetic Agents in Reducing Post-operative Opioid Requirements Following Rhinoplasty

NCT04377204
View directory record Official record
Conditions
Pain, Postoperative, Local Anesthetic
Interventions
marcaine bupivacaine, Lidocaine
Drug
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Jun 26, 2026, 2:08 AM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

Efficacy of Liposomal Bupivacaine Post Septorhinoplasty

NCT05964868
View directory record Official record
Conditions
Rhinoplasty, Pain Management
Interventions
Liposomal Bupivacaine, 0.25% bupivacaine with 1:200,000 epinephrine, Placebo - Saline solution
Drug · Other
Lead sponsor
Jessyka Lighthall
Other
Eligibility
18 Years to 99 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Phase 2 Interventional Results available

Postoperative Pain Management in Rhinoplasty

NCT03584152
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Norco 5Mg-325Mg Tablet, Tylenol 325Mg Caplet, Ibuprofen 200 mg
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Jun 26, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Cartilage Remodeling Using Low-Temperature Radiofrequency for Nasal Airway Reconstruction

NCT07032675
View directory record Official record
Conditions
Nasal Valve Collapse, Nose Enhancement
Interventions
Low-temperature radio-frequency reshaping of autologous cartilage nasal and/or auricular cartilage
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 30, 2025 · Synced Jun 26, 2026, 2:08 AM EDT
Terminated Phase 2 Interventional Results available

DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty

NCT01982760
View directory record Official record
Conditions
Postoperative Ecchymosis
Interventions
DDAVP
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Lyndhurst, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Jun 26, 2026, 2:08 AM EDT
Enrolling by invitation Phase 3 Interventional

Antibiotic Prophylaxis in Rhinoplasty

NCT04194216
View directory record Official record
Conditions
Nasal Obstruction, Nasal Surgical Procedures
Interventions
Intra-operative single intravenous(iv) dose of "cephalexin" 2 g or "clindamycin" 900 mg., Intra-operative single dose (iv) of "cephalexin" 2 g or "clindamycin" 900 mg and postoperative oral dose of "cephalexin" 250mg (every 4 hours) or "clindamycin" 150mg(every 6 hours) for 3 days
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Not applicable Interventional Results available

The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery

NCT01164644
View directory record Official record
Conditions
Ecchymosis
Interventions
Arnica montana, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Jun 26, 2026, 2:08 AM EDT
Withdrawn Early Phase 1 Interventional

Betadine Effect on Nasal Mucosa Cilia

NCT04457765
View directory record Official record
Conditions
Rhinoplasty
Interventions
Povidone-Iodine (PVP-I)
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Phase 2 Interventional Results available

A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty

NCT01684020
View directory record Official record
Conditions
Subjects Requesting and Requiring an Open Rhinoplasty
Interventions
ARTISS human fibrin sealant
Biological
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 1, 2020 · Synced Jun 26, 2026, 2:08 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty

NCT03498261
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use
Interventions
Gabapentin, Placebos
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Jun 26, 2026, 2:08 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia

NCT01746940
View directory record Official record
Conditions
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
Interventions
Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution, Placebo Topical Solution
Drug
Lead sponsor
Lannett Company, Inc.
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Bridgeport, Connecticut • Plano, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Jun 26, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Surgical Rhinoplasty Using PDO Threads

NCT04769427
View directory record Official record
Conditions
Nasal Defect
Interventions
PDO max threads
Device
Lead sponsor
DeNova Research
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Jun 26, 2026, 2:08 AM EDT
Withdrawn Not applicable Interventional

Nasal Dilator Strips for Rhinoplasty

NCT02787421
View directory record Official record
Conditions
Nasal Valve Compromise
Interventions
Breathe-Rite Nasal Dilator Strip
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Jun 26, 2026, 2:08 AM EDT