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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail

NCT02267356
View directory record Official record
Conditions
Onychomycosis
Interventions
VT-1161, Placebo
Drug
Lead sponsor
Viamet
Industry
Eligibility
18 Years to 70 Years
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
33
States / cities
Birmingham, Alabama • Tucson, Arizona • Oceanside, California + 29 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 3, 2026, 8:03 AM EDT
Not listed Not applicable Interventional

Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis

NCT06074315
View directory record Official record
Conditions
Distal Lateral Subungual Onychomycosis, Onychomycosis
Interventions
Nail Genesis DLSO Product, Nail Genesis DLSO Product (vehicle only)
Device
Lead sponsor
Nail Genesis LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
10
States / cities
Fayetteville, Arkansas • Montclair, California • Sacramento, California + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Sep 3, 2026, 8:03 AM EDT
Not listed Phase 2 Interventional

To Evaluate Hallux Terbinafine Subungual Gel (HSG) in the Treatment of Onychomycosis

NCT05135910
View directory record Official record
Conditions
Onychomycosis of Toenail
Interventions
Hallux Terbinafine Subungual Gel
Drug
Lead sponsor
Hallux, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Mesa, Arizona • Parker, Colorado • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Cumulative Irritation Test

NCT00781664
View directory record Official record
Conditions
Tinea Pedis
Interventions
AN2718, AN2718, Sodium Lauryl Sulfate
Other · Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 3, 2026, 8:03 AM EDT
Terminated Phase 3 Interventional

Safety and Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails

NCT01208129
View directory record Official record
Conditions
Onychomycosis
Interventions
NAB001, Placebo control
Drug
Lead sponsor
Promius Pharma, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
25
States / cities
Tucson, Arizona • Phoenix, Arkansas • Rogers, Arkansas + 22 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioequivalency Study of Terbinafine Tablets Under Fed Conditions

NCT00602251
View directory record Official record
Conditions
Onychomycosis
Interventions
Terbinafine
Drug
Lead sponsor
Roxane Laboratories
Industry
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional

Pilot Study to Evaluate Plasma Treatment of Onychomycosis

NCT01819051
View directory record Official record
Conditions
Onychomycosis
Interventions
MOE Antimicrobial Plasma Treatment System
Device
Lead sponsor
Moe Medical Devices
Industry
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 2 Interventional Results available

Efficacy and Safety Study of 4 Dose Regimens of Oral Albaconazole in Subjects With Distal Subungual Onychomycosis

NCT00730405
View directory record Official record
Conditions
Onychomycosis
Interventions
Albaconazole 100mg, Albaconazole 200mg, Albaconazole 400mg, Placebo 400 mg
Drug
Lead sponsor
Stiefel, a GSK Company
Industry
Eligibility
18 Years to 75 Years
Enrollment
582 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
29
States / cities
Birmingham, Alabama • Tucson, Arizona • Beverly Hills, California + 25 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2018 · Synced Sep 3, 2026, 8:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation

NCT00224926
View directory record Official record
Conditions
Tinea Capitis
Interventions
Scalp Brushing
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
2 Years to 5 Years
Enrollment
446 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 18, 2011 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Iontophoretic Application of Terbinafine Gel to the Large Toe Nail

NCT00768768
View directory record Official record
Conditions
Onychomycosis
Interventions
Electrokinetic Transungual System (ETS) - Terbinafine Gel, ETS-Terbinafine Gel
Other
Lead sponsor
Transport Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Mar 11, 2009 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 3 Interventional Results available

Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.

NCT00356915
View directory record Official record
Conditions
Onychomycosis
Interventions
Itraconazole 100mg capsules, Itraconazole 200mg tablets, Placebo tablets
Drug
Lead sponsor
Stiefel, a GSK Company
Industry
Eligibility
16 Years to 75 Years
Enrollment
1,381 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
52
States / cities
Birmingham, Alabama • Tuscon, Arizona • Hot Springs, Arkansas + 43 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional

Diode Laser Treatment of Onychomycosis

NCT01452490
View directory record Official record
Conditions
Onychomycosis
Interventions
Diode Laser Treatment
Device
Lead sponsor
ConBio, a Cynosure Company
Industry
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
New London, Connecticut • Westbrook, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 4 Interventional Results available

An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Disease of the Toenail in Children and Adolescents

NCT03405818
View directory record Official record
Conditions
Onychomycosis, Tinea Unguium
Interventions
Tavaborole 5% Topical Solution
Drug
Lead sponsor
Pfizer
Industry
Eligibility
72 Months to 203 Months
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
12
States / cities
Madera, California • Palo Alto, California • Washington D.C., District of Columbia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 1 Interventional

1320 nm Nd:YAG Laser for Improving the Appearance of Onychomycosis

NCT01498393
View directory record Official record
Conditions
Fungal Nail Infection
Interventions
Laser treatment
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study Comparing Ketoconazole Shampoo, 2% and Ketoconazole 2% Shampoo (RS) in the Treatment of Tinea Versicolor.

NCT06305637
View directory record Official record
Conditions
Tinea Versicolor
Interventions
Ketoconazole Shampoo, 2%, Ketoconazole Shampoo, 2% (Reference Standard), Placebo
Drug
Lead sponsor
Sun Pharmaceutical Industries, Inc.
Industry
Eligibility
18 Years and older
Enrollment
430 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Hawthorne, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 3, 2026, 8:03 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study

NCT07245667
View directory record Official record
Conditions
Tinea Pedis
Interventions
1% Tolnaftate Stick Formula A, 1% Tolnaftate Stick Formula B, 1% Tolnaftate Stick Formula C
Drug
Lead sponsor
Propedix, Inc.
Industry
Eligibility
16 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Framingham, Massachusetts • Milford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment of Onychomycosis Using a 0.65 Millisecond Pulsed Nd:YAG 1064 nm Laser

NCT01666002
View directory record Official record
Conditions
Onychomycosis
Interventions
Laser Treatment (Pulsed Nd:YAG 1064 nm Laser)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 29, 2016 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Safety and Pharmacokinetics of Efinaconazole Topical Solution in Subjects With Mild to Severe Onychomycosis

NCT02812771
View directory record Official record
Conditions
Onychomycosis
Interventions
Efinaconazole
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
6 Years to 16 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
9
States / cities
Birmingham, Alabama • Fountain Valley, California • Santa Rosa, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Pediatric Subjects With Tinea Corporis

NCT02227290
View directory record Official record
Conditions
Tinea Corporis
Interventions
Naftin Cream, Placebo Cream
Drug
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
2 Years to 17 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
14
States / cities
Tucson, Arizona • Encino, California • Fremont, California + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2016 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 2 Interventional

Topical Gel Anti-Fungal Agent for Tinea Unguium

NCT00253305
View directory record Official record
Conditions
Onychomycosis
Interventions
Organogel of naftifine, 2%, Organogel of terbinafine, 2%, Organogel of naftifine, 6%, Organogel of terbinafine, 6%
Drug
Lead sponsor
MediQuest Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
5
States / cities
Birmingham, Alabama • Tucson, Arizona • Miami Beach, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated May 29, 2007 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 mg Albaconazole as a Tablet Versus Albaconazole as a Capsule

NCT01039883
View directory record Official record
Conditions
Onychomycosis
Interventions
Albaconazole tablet 400mg, Albaconazole 100mg capsules, then albaconazole 400mg tablet
Drug
Lead sponsor
Stiefel, a GSK Company
Industry
Eligibility
18 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Sep 3, 2026, 8:03 AM EDT
Completed No phase listed Observational

An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection

NCT05202366
View directory record Official record
Conditions
Fungal Infection, Onychomycosis, Tinea Unguium
Interventions
CGB-400 Topical Gel
Drug
Lead sponsor
CAGE Bio Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 3, 2026, 8:03 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Tinea Pedis

NCT05493488
View directory record Official record
Conditions
Tinea Pedis
Interventions
DBI-001 Gel, DBI-002 Gel, Aqueous Gel
Biological
Lead sponsor
DermBiont, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Portland, Oregon • Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail

NCT00453271
View directory record Official record
Conditions
Onychomycosis
Interventions
NB-002, Vehicle control
Drug
Lead sponsor
NanoBio Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
13
States / cities
Miami, Florida • Boise, Idaho • Evansville, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated May 22, 2013 · Synced Sep 3, 2026, 8:03 AM EDT