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Showing 1–24 of 216 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Risk for HIV Infection Clear all
Completed Not applicable Interventional Accepts healthy volunteers

SAVA Syndemic Risk Reduction for African American Couples

NCT04766697
View directory record Official record
Conditions
SAVA
Interventions
Risk-Reduction Sessions
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 49 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Sep 23, 2026, 3:27 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves

NCT03278990
View directory record Official record
Conditions
HIV Prevention
Interventions
Value Affirmation and Future Selves Combination, Control writing exercise
Behavioral
Lead sponsor
Stuart Fisk
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Sep 23, 2026, 3:27 PM EDT
Completed No phase listed Observational Results available

A Prospective, Longitudinal Study of Endothelial Function in HIV/HCV Coinfected Subjects

NCT02597790
View directory record Official record
Conditions
HIV, Hepatitis C
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

WeExPAnd: PrEP Demonstration Project Among Women at Risk for HIV Infection - Preexposure Prophylaxis (PrEP)

NCT04373551
View directory record Official record
Conditions
HIV-infection/AIDS
Interventions
Cultural adaptation of a patient-provider communication tool
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 1 Interventional

Reducing Drug Use and HIV Risk in Drug-dependent Adults Arrested for Prostitution

NCT01560221
View directory record Official record
Conditions
Substance-related Disorders, HIV Risk Behavior
Interventions
Therapeutic Workplace, Methadone, Buprenorphine
Behavioral · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Sep 23, 2026, 3:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TelePrEP for At-risk Youth in Colorado

NCT05520905
View directory record Official record
Conditions
Hiv
Interventions
TelePrEP
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
14 Years to 24 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Sep 23, 2026, 3:27 PM EDT
Completed No phase listed Observational

Vascular Subphenotypes of Lung Disease in HIV & COPD

NCT01581086
View directory record Official record
Conditions
Pulmonary Artery Hypertension
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 23, 2026, 3:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits

NCT00001500
View directory record Official record
Conditions
Acquired Immunodeficiency Syndrome, Alcoholism, HIV Infection, Neoplasm, Smoking
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
4,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional

AWAITS: A Web-based E-health Application for Active Illicit Opioid Users

NCT03402672
View directory record Official record
Conditions
Opioid-use Disorder, IV Drug Usage, Overdose, Drug Addiction, Substance Use Disorders
Interventions
self-administered, e-health application
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

PrEP SMART Phase I Trial

NCT02895893
View directory record Official record
Conditions
At Risk for HIV
Interventions
PrEP Smart
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 23, 2026, 3:27 PM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Naltrexone for Overdose Prevention

NCT06633900
View directory record Official record
Conditions
Overdose Accidental
Interventions
IM naltrexone, Usual Care
Drug · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Active, not recruiting Not applicable Interventional

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services

NCT04738825
View directory record Official record
Conditions
Opioid-use Disorder, HIV Prevention Program
Interventions
Contingency Management with stepped care to PrEP adherence and support services (CoMPASS)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Bridgeport, Connecticut • Danbury, Connecticut • New Haven, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluating the Safety and Tolerability of Antiretroviral Drug Regimens Used as Pre-Exposure Prophylaxis to Prevent HIV Infection in At-Risk Men Who Have Sex With Men and in At-Risk Women

NCT01505114
View directory record Official record
Conditions
HIV Infection
Interventions
Maraviroc, Emtricitabine, Tenofovir disoproxil fumarate, Maraviroc placebo, Emtricitabine placebo, Tenofovir disoproxil fumarate placebo
Drug · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
594 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
12
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Sep 23, 2026, 3:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults

NCT06444360
View directory record Official record
Conditions
HIV
Interventions
IMPACT, eSOC
Behavioral
Lead sponsor
Westat
Other
Eligibility
16 Years to 24 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 2 Interventional

Brief Introductory Therapy for Opioid Dependence

NCT00406484
View directory record Official record
Conditions
Opiate Dependence, HIV Infections
Interventions
Standard drug counseling, BDRC
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Y2Prevent: Preventing Drug Use and HIV Through Empowerment, Social Support and Mentorship (Y2P)

NCT04504981
View directory record Official record
Conditions
HIV, Drug Use
Interventions
Y2Prevent
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2023 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 2 Interventional

Extended-Release Naltrexone to Treat Methamphetamine Dependence in Men Who Have Sex With Men (MSM)

NCT01449565
View directory record Official record
Conditions
Amphetamine-Related Disorders
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
18 Years to 65 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia

NCT00246376
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, HIV Infections, Hyperlipidemia, Hypertriglyceridemia, Insulin Resistance, Atherosclerosis
Interventions
Diet, Exercise, Niacin, Fenofibrate, Placebos
Behavioral · Drug · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2016 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Young Women's Health CoOp (Cooperative) in Cape Town

NCT02677025
View directory record Official record
Conditions
HIV, Substance Abuse
Interventions
Young Women's Health CoOp (YWHC), HIV Counseling/Testing
Behavioral
Lead sponsor
RTI International
Other
Eligibility
16 Years to 21 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 23, 2026, 3:27 PM EDT
Not listed Phase 1Phase 2 Interventional

Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk Reduction

NCT00609089
View directory record Official record
Conditions
Heroin Dependence, Opiate Dependence, Substance Dependence
Interventions
CRAFT-T, Treatment as usual
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 13, 2012 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

eTest: Real-time, Remote Monitoring System for Home-based HIV Testing Among High-risk Men Who Have Sex With Men

NCT03654690
View directory record Official record
Conditions
HIV Infections
Interventions
HIV self-test, Counseling
Diagnostic Test · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
811 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Brief Acceptance and Commitment Therapy for HIV-infected At-risk Drinkers

NCT03974061
View directory record Official record
Conditions
Treatment
Interventions
Brief Acceptance and Commitment Therapy, Brief Alcohol Intervention
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementation Research for Vulnerable Women in South Africa

NCT02733003
View directory record Official record
Conditions
HIV, Substance Abuse
Interventions
Women's Health CoOp (WHC)
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
564 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Game Plan for PrEP

NCT04973267
View directory record Official record
Conditions
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Interventions
Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 23, 2026, 3:27 PM EDT