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ClinicalTrials.gov public records Last synced Oct 8, 2026, 1:05 PM EDT

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Showing 97–120 of 217 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Risk for HIV Infection Clear all
Completed Phase 3 Interventional

A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes

NCT00076232
View directory record Official record
Conditions
HIV Infections, HIV Seronegativity, Herpes Genitalis
Interventions
Acyclovir, Acyclovir placebo
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
3,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
3
States / cities
San Francisco, California • New York, New York • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 30, 2010 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional

Youth Services Navigation Intervention for HIV+ Youth Being Released From or At-risk for Incarceration

NCT03584932
View directory record Official record
Conditions
HIV/AIDS
Interventions
LINK2 Youth Services Navigation Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
16 Years to 25 Years · Male only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 8, 2026, 1:05 PM EDT
Active, not recruiting Phase 2 Interventional

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

NCT04929028
View directory record Official record
Conditions
AIDS-Related Anal Carcinoma, Anal Margin Squamous Cell Carcinoma, Anal Non-Keratinizing Squamous Cell Carcinoma, Anal Squamous Cell Carcinoma, HIV Infection, Rectal Squamous Cell Carcinoma, Stage II Rectal Cancer AJCC v8, Stage IIB Anal Cancer AJCC v8, Stage III Anal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8
Interventions
Anoscopy, Biospecimen Collection, Capecitabine, Colonoscopy, Computed Tomography, Digital Rectal Examination, Echocardiography Test, Fludeoxyglucose F-18, Fluorouracil, Intensity-Modulated Radiation Therapy, Lymph Node Biopsy, Magnetic Resonance Imaging, Mitomycin, Nivolumab, Positron Emission Tomography, Proctoscopy, Questionnaire Administration, Sigmoidoscopy
Procedure · Drug · Other + 2 more
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
14
States / cities
San Francisco, California • Washington D.C., District of Columbia • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 8, 2026, 1:05 PM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Naltrexone for Overdose Prevention

NCT06633900
View directory record Official record
Conditions
Overdose Accidental
Interventions
IM naltrexone, Usual Care
Drug · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 3 Interventional

Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users

NCT00228007
View directory record Official record
Conditions
Depression, Substance-Related Disorders, HIV Infections
Interventions
Antidepressant Medication
Drug
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
265 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 22, 2013 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional

Violence and HIV Risk Among Women

NCT01695694
View directory record Official record
Conditions
HIV Risk Reduction
Interventions
supporting positive and healthy relationships, community support group
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2014 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

PrEP SMART Phase I Trial

NCT02895893
View directory record Official record
Conditions
At Risk for HIV
Interventions
PrEP Smart
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Friendship Based HIV/STI (Sexually Transmitted Infections) Intervention for African American Females

NCT00109421
View directory record Official record
Conditions
Sexual Behavior, Sexually Transmitted Diseases, HIV Infections
Interventions
Project ÒRÉ
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
14 Years to 21 Years · Female only
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

The HJ MILE HIV Prevention Intervention for Post-incarcerated Men

NCT01427543
View directory record Official record
Conditions
HIV, Risk Reduction Behavior
Interventions
MILE intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Male only
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 8, 2026, 1:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

NCT05816083
View directory record Official record
Conditions
Substance Use Disorders, HIV Infections
Interventions
Virtual Reality Tool
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
15 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

HIV Prevention Counseling for Men Who Have Sex With Men

NCT00000931
View directory record Official record
Conditions
HIV Infections
Interventions
Behavioral intervention, Risk-reduction counseling
Behavioral
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older · Male only
Enrollment
4,350 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
6
States / cities
San Francisco, California • Denver, Colorado • Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2008 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of Many Men, Many Voices, An STD/HIV Prevention Intervention for Black MSM

NCT00137631
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
Many Men, Many Voices (3MV)
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
341 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2010 · Synced Oct 8, 2026, 1:05 PM EDT
Completed No phase listed Observational

Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans Infection

NCT00001701
View directory record Official record
Conditions
Cryptococcosis
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1998
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 3 Interventional

Case Management Alternatives for African American Women at High Risk for HIV

NCT00780260
View directory record Official record
Conditions
HIV
Interventions
strengths-based case management
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
562 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 11, 2013 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional Results available

Nurse-Led Community Health Worker Adherence Model in 3HP Delivery Among Homeless Adults at Risk for TB Infection and HIV

NCT03702049
View directory record Official record
Conditions
Latent Tuberculosis Infection
Interventions
Nurse-led Community Health Worker TBI (RN/CHW TBI) program
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional

Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members

NCT00000703
View directory record Official record
Conditions
Lymphoma, Non-Hodgkin, HIV Infections
Interventions
Bleomycin sulfate, Vincristine sulfate, Doxorubicin hydrochloride, Cyclophosphamide, Allopurinol, Methotrexate, Cytarabine, Leucovorin calcium, Zidovudine, Dexamethasone
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
19 Years to 69 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1990
U.S. locations
14
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Interventional Study of Mucosal and Antimicrobial Responses to Repeated Vaginal Applications of Tenofovir Gel in HIV Uninfected Women

NCT00594373
View directory record Official record
Conditions
HIV Infections
Interventions
Tenofovir gel, Tenofovir gel placebo
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 50 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer Outreach and Navigation Intervention to Increase PrEP Uptake Among Women at High Risk for HIV

NCT03226873
View directory record Official record
Conditions
Pre-exposure Prophylaxis, HIV-1-infection
Interventions
Peer Navigation
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Short-Term PrEP Uptake for MSM With Episodic High-Risk for HIV

NCT02495779
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
emtricitabine/tenofovir, CBT-based counseling
Drug · Behavioral
Lead sponsor
James Egan
Other
Eligibility
18 Years and older · Male only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 2 Interventional

Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV

NCT06538285
View directory record Official record
Conditions
Methamphetamine Use Disorder
Interventions
Ketamine, Psychotherapy
Drug · Behavioral
Lead sponsor
Nicky Mehtani, MD, MPH
Other
Eligibility
18 Years to 69 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francicso, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

FASTLANE II: Reducing Sex, Drug, and Mental Health Risk

NCT04109014
View directory record Official record
Conditions
Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
Interventions
FASTLANE II
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 8, 2026, 1:05 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics

NCT06684613
View directory record Official record
Conditions
Sexual Risk Behavior for HIV-infection, Reproductive Health
Interventions
PrEP Decision Aid, Generic Information
Device · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Positive Choice: Prevention for Positive Health

NCT00447707
View directory record Official record
Conditions
HIV Infections, Sexual Risk Behavior, Substance Use Risks
Interventions
Positive Choice
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
5
States / cities
Oakland, California • San Francisco, California • San Leandro, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 8, 2026, 1:05 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women

NCT00074425
View directory record Official record
Conditions
HIV Infections
Interventions
BufferGel, PRO 2000/5 Gel, Placebo gel
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older · Female only
Enrollment
3,101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Oct 8, 2026, 1:05 PM EDT