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ClinicalTrials.gov public records Last synced Oct 22, 2026, 10:23 PM EDT

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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Risky Substance Use Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Nexus of Risk: Sexual Assault, Alcohol Use, and Risky Sex Among College Women

NCT05892692
View directory record Official record
Conditions
Sexual Assault, Substance Use, Risky Health Behavior, Ema
Interventions
Ecological Momentary Intervention
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 22, 2026, 10:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

90-Day Online Substance Use Program

NCT03069118
View directory record Official record
Conditions
Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse, Drug Use Disorders
Interventions
Treatment - Workit Health Online Program, Control - Resource List
Behavioral
Lead sponsor
Workit Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 22, 2026, 10:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

First Years Away From Home: Letting Go and Staying Connected

NCT03227809
View directory record Official record
Conditions
Substance Abuse, Risk Reduction, RIsky Sexual Behavior
Interventions
Handbook condition, Handbook plus condition
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
17 Years to 22 Years
Enrollment
910 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Pullman, Washington
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional

Preventing Substance Use and Risky Behavior Among Rural African American Youth

NCT00535704
View directory record Official record
Conditions
Risky Sexual Behavior
Interventions
Strong African American Families-Teen Program, FUEL
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
14 Years to 17 Years
Enrollment
502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 22, 2026, 10:23 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder

NCT06577454
View directory record Official record
Conditions
Opioid Use Disorder, Healthy Volunteers
Interventions
TMS (MagVenture MagPro 100 with MagOption)
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Health in Pregnancy (HIP) Study

NCT00540319
View directory record Official record
Conditions
Pregnancy
Interventions
HIP
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
5
States / cities
Oakland, California • San Francisco, California • San Jose, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2013 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional

Impact of Personalized Feedback Alone on Substance Use Behaviors

NCT01501318
View directory record Official record
Conditions
Substance Abuse
Interventions
Personalized feedback report, Personalized feedback report plus education
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 105 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional

Trauma Informed Prevention for Substance Use and Risky Sex

NCT03710720
View directory record Official record
Conditions
Substance Use, HIV/AIDS
Interventions
TIPS app, Trauma Focused-Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 18 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 22, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional

Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain

NCT06991205
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Upper Extremity Pain, Risky Substance Use
Interventions
Web-TIRELESS, Web-MEUC
Behavioral · Other
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional

Mechanisms of Risky Alcohol Use in Young Adults: Linking Sleep to Reward- and Stress-Related Brain Function

NCT05684094
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Sleep extension and advance, Regular sleep duration and timing
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 24 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The STop UNhealthy Substance Use Now Trial

NCT06524232
View directory record Official record
Conditions
Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder, Drinking, Alcohol, Substance Use
Interventions
Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI)
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Cincinnati, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Novel Prevention Intervention Program to Reduce Risky Patterns of Substance Use Among Emerging Adults

NCT06287203
View directory record Official record
Conditions
Substance Use
Interventions
Addiction Risk Feedback Program
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 25 Years
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Parenting in 2 Worlds Multisite Trial

NCT06324318
View directory record Official record
Conditions
Parenting, Mental Health Wellness 1, Substance Use, Risky Health Behavior
Interventions
Parenting in 2 Worlds (P2W), Healthy Families in 2 Worlds (HF2W)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • Denver, Colorado • Saint Paul, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Peer MI for Substance-using Emerging Adults

NCT03264872
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Peer-Enhanced Motivational Interviewing, Waitlist Control
Behavioral · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 29 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 2 Interventional

The iHealth Study in College Students

NCT00183131
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Unhealthy Alcohol Use, Risky Alcohol Consumption Amounts, Hazardous Alcohol Use
Interventions
Brief Personalized Feedback
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
4,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2010 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

NCT06366633
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
Interventions
Web-TIRELESS
Behavioral
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 3 Interventional

ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems

NCT00183105
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Consumption
Interventions
Brief Intervention (adaptation of motivational interviewing)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2010 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

STUN (STop UNhealthy) Alcohol Use Now! Implementing Evidence-Based Services for Unhealthy Alcohol Use in Primary Care

NCT04317989
View directory record Official record
Conditions
Risky Health Behavior, Drinking, Alcohol, Alcohol Use Disorder, Drinking, Binge, Drinking Excessive
Interventions
Practice Facilitation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
7
States / cities
Asheville, North Carolina • Charlotte, North Carolina • Greensboro, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Oct 22, 2026, 10:23 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Community Youth Development Study: A Test of Communities That Care

NCT01088542
View directory record Official record
Conditions
Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior, Violence, Depression, Anxiety, Suicide, Sexually Transmitted Infection, Educational Attainment
Interventions
Communities That Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
10 Years and older
Enrollment
52,323 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project IntERact Study

NCT03940716
View directory record Official record
Conditions
Violence, Substance Use, Criminal Behavior
Interventions
IntERact
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
16 Years to 24 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 4 Interventional Results available

Neural Mechanisms of Disulfiram Effects

NCT02735577
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Disulfiram
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Michigan SPARC Trial

NCT04861792
View directory record Official record
Conditions
Alcohol, Drinking, Alcohol Use Disorder (AUD)
Interventions
Michigan SPARC Quality Improvement Intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
9,590 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Prevention of Alcohol and Risky Sex for Older Teens

NCT03521115
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders, Alcohol Impairment, Alcohol Withdrawal, Alcohol Abstinence, Alcohol; Harmful Use, Sex Behavior, Sexual Aggression, Sexual Harassment, Relation, Interpersonal
Interventions
Smart Choices 4 Teens
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
16 Years to 17 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 22, 2026, 10:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optimizing a Drug Abuse Prevention Program for Dissemination

NCT03125291
View directory record Official record
Conditions
Substance Abuse, Mental Health, Educational Problems
Interventions
Bridges 4-week Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
10 Years to 15 Years
Enrollment
664 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 22, 2026, 10:23 PM EDT