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ClinicalTrials.gov public records Last synced Sep 11, 2026, 5:32 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Rotator Cuff Clear all
Completed Not applicable Interventional

Home Exercise vs PT for Reverse Total Shoulder Arthroplasty

NCT03719859
View directory record Official record
Conditions
Shoulder Arthritis, Rotator Cuff Tear Arthropathy
Interventions
Physical Therapy, Home Therapy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
7
States / cities
Denver, Colorado • Washington D.C., District of Columbia • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 11, 2026, 5:32 AM EDT
Not yet recruiting Phase 1 Interventional

Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery

NCT07803250
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
BPC-157, Sham (No Treatment)
Drug · Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Do Relaxation Exercises Decrease Postoperative Pain After Arthroscopic Rotator Cuff Repair?

NCT04249089
View directory record Official record
Conditions
Rotator Cuff Injuries
Interventions
Relaxation video and pamplet
Behavioral
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Egg Harbor, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Sep 11, 2026, 5:32 AM EDT
Not listed Phase 4 Interventional

Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair

NCT05974423
View directory record Official record
Conditions
Postoperative Pain, Acute, Opioid Use, Labral Tear, Glenoid
Interventions
Tylenol, Ibuprofen, and Oxycodone, Tylenol and Ibuprofen only
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
15 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Sep 11, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Following Hip Arthroscopy

NCT04113759
View directory record Official record
Conditions
Labral Tear, Glenoid, Femoral Acetabular Impingement
Interventions
Blood Flow Restriction Rehabilitative Therapy, Sham BFR Rehabilitative Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 11, 2026, 5:32 AM EDT
Not yet recruiting Not applicable Interventional

H-Wave® Device Stimulation for Post-operative Rotator Cuff Repair Surgery

NCT07501949
View directory record Official record
Conditions
Rotator Cuff Tear Surgical Repair
Interventions
Routine post-surgical care plus H-Wave® Device Stimulation (HWDS), Routine post-surgical care
Device · Other
Lead sponsor
Electronic Waveform Lab
Industry
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Overland Park, Kansas • Kansas City, Missouri • Lee's Summit, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Impact of Humeral Component Version on Outcomes Following RTSA

NCT03111147
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
0 degrees humeral component version, 30 degrees humeral component retroversion
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Bridge Device for Surgical Pain for Rotator Cuff Surgery

NCT06071884
View directory record Official record
Conditions
Pain, Rotator Cuff Injuries
Interventions
Bridge Percutaneous Nerve Field Stimulator
Device
Lead sponsor
Steven Orebaugh
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
West Mifflin, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears

NCT05444465
View directory record Official record
Conditions
Rotator Cuff Injuries
Interventions
Isolated Bioinductive Repair, Completion and Repair
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
8
States / cities
Rome, Georgia • Rockford, Illinois • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine in Rotator Cuff Repair

NCT03738696
View directory record Official record
Conditions
Rotator Cuff Injury
Interventions
Exparel, Ropivacaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 11, 2026, 5:32 AM EDT
Active, not recruiting Not applicable Interventional

Rotator Cuff Sparing Total Arthroplasty

NCT01961986
View directory record Official record
Conditions
Osteoarthritis, Inflammatory Arthritis
Interventions
TSR - traditional subscapularis release, TSR - rotator cuff sparing
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Terminated Not applicable Interventional Results available

Non-Surgical Treatment for Rotator-Cuff Tears Using Platelet-Rich-Plasma

NCT02246530
View directory record Official record
Conditions
Partial Tear of Rotator Cuff, Tendinopathy of Rotator Cuff
Interventions
PRP injection into PTRCT, Subacromial steroid bursal injection
Procedure · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telerehabilitation After Shoulder Arthroplasty

NCT05499728
View directory record Official record
Conditions
Arthritis Shoulder Glenohumoral Joint, Rotator Cuff Tear Arthropathy, Arthropathy Shoulder
Interventions
Telerehabilitation; physical therapy via telecommunication device (i.e. online video conferencing)
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Embolization Treatment of Chronic Refractory Shoulder Tendinopathy

NCT06095050
View directory record Official record
Conditions
Shoulder Pain, Tendinopathy, Rotator Cuff Tendinitis, Rotator Cuff Tendinosis, Embolization, Arterial Occlusion
Interventions
Embolization, Physical Therapy
Device · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Recruiting No phase listed Observational

Zimmer ActivBraid Rotator Cuff Repair (RCR) Study

NCT06971497
View directory record Official record
Conditions
Rotator Cuff Repair of the Shoulder
Interventions
ActivBraid™Collagen Co-Braid suture (Zimmer Biomet)
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Punch vs. Drill Tunnel Use for Anchor Tunnel Creation and Correlation With Post-operative Pain

NCT04288570
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
suture anchor socket creation with punch, suture anchor socket creation with drill
Procedure
Lead sponsor
Matt Smith
Other
Eligibility
18 Years to 80 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes

NCT02588027
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Automatic Multimodal Assessment of Occurrence and Intensity of Pain for Research and Clinical Use

NCT04833244
View directory record Official record
Conditions
Rotator Cuff Injuries
Interventions
Triangular Forearm Support, Placebo
Behavioral
Lead sponsor
Manhattan Physical Medicine and Rehabilitation, LLP
Other
Eligibility
21 Years and older
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Sep 11, 2026, 5:32 AM EDT
Recruiting No phase listed Observational

FX Shoulder Solutions Retrospective / Prospective Clinical Study

NCT06077942
View directory record Official record
Conditions
Rotator Cuff Syndrome of Shoulder and Allied Disorders, Osteoarthritis Shoulder, Fracture, Shoulder
Interventions
FX Artificial Shoulder Prosthesis
Device
Lead sponsor
FX Shoulder Solutions
Industry
Eligibility
Not listed
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
2
States / cities
Gilbert, Arizona • The Villages, Florida
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 11, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Biomarkers to Predict Rotator Cuff Repair Healing on Postoperative MRI

NCT07781553
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
MRN
Diagnostic Test
Lead sponsor
Joseph W. Galvin
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Post-Operative Quality of Life Evaluation for Different Anesthesia Techniques for Arthroscopic Shoulder Surgery

NCT01355757
View directory record Official record
Conditions
Rotator Cuff Injury
Interventions
Baxter INFUSOR System, Single Injection of Local Anesthetic
Device · Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2014 · Synced Sep 11, 2026, 5:32 AM EDT
Active, not recruiting Not applicable Interventional

Sling vs No Sling After Reverse Total Shoulder Arthroplasty

NCT06092996
View directory record Official record
Conditions
Shoulder Disease, Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions
Time of Sling Use
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Single Shot Liposomal Bupivicaine in Rotator Cuff Surgery

NCT03822182
View directory record Official record
Conditions
Rotator Cuff Tear, Pain, Postoperative
Interventions
liposomal bupivicaine, Dexamethasone
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Avon, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 11, 2020 · Synced Sep 11, 2026, 5:32 AM EDT
Completed No phase listed Observational Results available

Safety of Treatment of Shoulder Repair

NCT04552119
View directory record Official record
Conditions
Rotator Cuff
Interventions
HEALICOIL Knotless PEEK, HEALICOIL Knotless REGENESORB
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Redwood City, California • Colorado Springs, Colorado • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 11, 2026, 5:32 AM EDT