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Showing 1–24 of 112 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Rotator Cuff Repair Clear all
Not listed Phase 4 Interventional

Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair

NCT05974423
View directory record Official record
Conditions
Postoperative Pain, Acute, Opioid Use, Labral Tear, Glenoid
Interventions
Tylenol, Ibuprofen, and Oxycodone, Tylenol and Ibuprofen only
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
15 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Liposomal Bupivacaine for Pain Control After Rotator Cuff Repair

NCT03692546
View directory record Official record
Conditions
Rotator Cuff Tear, Postoperative Pain
Interventions
Liposomal bupivacaine (LB)
Drug
Lead sponsor
Orthopaedic & Neurosurgery Specialists
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Greenwich, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 1, 2018 · Synced Jul 22, 2026, 9:57 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair

NCT04345666
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Testosterone cypionate, Placebos
Drug
Lead sponsor
Orthopedic Institute, Sioux Falls, SD
Other
Eligibility
45 Years to 75 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Jul 22, 2026, 9:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Decellularized Human Placental Extracellular Matrix Tissue for Rotator Cuff Repair Augmentation

NCT07027735
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Rotator Cuff Repair with Allograft Patch, Rotator Cuff Repair with No Augmentation
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 22, 2026, 9:57 AM EDT
Not listed Not applicable Interventional

Sleep Quality and Pain Medication Use Following Arthroscopic Rotator Cuff Repair

NCT04278677
View directory record Official record
Conditions
Sleep Disturbance
Interventions
melatonin
Dietary Supplement
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Egg Harbor, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Jul 22, 2026, 9:57 AM EDT
Recruiting Not applicable Interventional

Prospective Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft Active Matrix (AM) vs. Standard of Care in Arthroscopic Rotator Cuff Repair

NCT05894265
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
ActiveMatrix® Dosage A, ActiveMatrix® Dosage B, Saline injection
Other · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 22, 2026, 9:57 AM EDT
Terminated Not applicable Interventional

Effectiveness of the Ivivi Torino II, Pulsed Radio Frequency Device, on Narcotic Use, Pain and Quality of Life Following Shoulder Arthroscopic Rotator Cuff Repair.

NCT01507818
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Ivivi Torino II, Inactive Sham device
Device
Lead sponsor
Amp Orthopedics, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
New Orleans, Louisiana • Jackson, Mississippi • Taos, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 8, 2012 · Synced Jul 22, 2026, 9:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes

NCT06361797
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Rotator cuff repair augmented with whole bone marrow, Rotator cuff repair augmented with concentrated bone marrow
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Columbia, Maryland • Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Jul 22, 2026, 9:57 AM EDT
Completed No phase listed Observational

Arthroscopic Surgical Outcome Study In Subjects With Rotator Cuff Tears

NCT00739947
View directory record Official record
Conditions
Rotator Cuff, Arthroscopic Surgery
Interventions
Observational study of the surgical outcome
Other
Lead sponsor
Pfizer
Industry
Eligibility
21 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
37
States / cities
Phoenix, Arizona • Sun City, Arizona • Sun City West, Arizona + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week

NCT01881776
View directory record Official record
Conditions
Postoperative Pain, Adverse Effects
Interventions
ISB
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2014 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Phase 4 Interventional Results available

Efficacy of Continuous Infusion Ropivacaine Interscalene Blocks

NCT02462382
View directory record Official record
Conditions
Full-thickness Rotator Cuff Tear
Interventions
Arthroscopic Rotator Cuff Repair, Ropivacaine, Saline
Procedure · Drug
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Jul 22, 2026, 9:57 AM EDT
Recruiting No phase listed Observational

Zimmer ActivBraid Rotator Cuff Repair (RCR) Study

NCT06971497
View directory record Official record
Conditions
Rotator Cuff Repair of the Shoulder
Interventions
ActivBraid™Collagen Co-Braid suture (Zimmer Biomet)
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Phase 4 Interventional

Measuring Opioid Use After Rotator Cuff Repair: Comparing the Effects of Standard vs. Extended-release Nerve Blocks

NCT05482113
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Liposomal bupivacaine, Bupivacaine Hcl 0.25% Inj
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional

Use of Human Dehydrated Umbilical Cord Allograft in Supraspinatus Tendon Repair

NCT03084068
View directory record Official record
Conditions
Shoulder Injury, Shoulder Sprain, Supraspinatus Tear
Interventions
Human dehydrated umbilical cord allograft, Placebo
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Wexford, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Partial Rotator Cuff Repair vs. Superior Capsular Reconstruction for Irreparable Rotator Cuff Tears

NCT04742452
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Superior Capusular Reconstruction, Partial Rotator Cuff Repair
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • Cleveland, Ohio • Willoughby, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 22, 2026, 9:57 AM EDT
Terminated Not applicable Interventional Results available

Treatment of Partial-Thickness Rotator Cuff Tears

NCT03734536
View directory record Official record
Conditions
Arthroscopic Surgical Treatment of High-grade (>50%) Partialthickness
Interventions
REGENETEN™ Bioinductive Implant, Arthroscopic repair of the high-grade (>50%) partial-thickness
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
10
States / cities
Gainesville, Florida • Jacksonville Beach, Florida • Rome, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Phase 3 Interventional Results available

Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery

NCT02713230
View directory record Official record
Conditions
Pain
Interventions
bupivacaine liposome injectable suspension, Placebo
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
17
States / cities
Mobile, Alabama • Englewood, Colorado • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jul 22, 2026, 9:57 AM EDT
Recruiting No phase listed Observational

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

NCT04209504
View directory record Official record
Conditions
Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis, Shoulder Disease, Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Arthropathy of Left Shoulder, Rotator Cuff Arthropathy of Right Shoulder, Rotator Cuff Repair
Interventions
Ultrasound, Ropivacaine, Bupivacaine, MediPines AGM100 Advanced Respiratory Monitoring System
Diagnostic Test · Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jul 22, 2026, 9:57 AM EDT
Withdrawn Not applicable Interventional

Trial of the Use of Doxycycline After Rotator Cuff Repair

NCT02388477
View directory record Official record
Conditions
Rotator Cuff Injury
Interventions
Doxycycline, sugar pill
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2016 · Synced Jul 22, 2026, 9:57 AM EDT
Recruiting Not applicable Interventional

Treatment of the Biceps With Concomitant Supraspinatus Tears

NCT05660031
View directory record Official record
Conditions
Supraspinatus Tear
Interventions
LHB Tenotomy, LHB Tenodesis
Procedure
Lead sponsor
La Tour Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Ann Arbor, Michigan • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Jul 22, 2026, 9:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Results of Rotator Cuff Repair

NCT01549912
View directory record Official record
Conditions
Shoulder Dislocation
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
35 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 5, 2015 · Synced Jul 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional Results available

Outcomes in Rotator Cuff Repair Using Graft Reinforcement

NCT01025037
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Conexa Reconstructive Tissue Matrix
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
40 Years to 70 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
6
States / cities
Phoenix, Arizona • Chicago, Illinois • Durham, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Jul 22, 2026, 9:57 AM EDT
Withdrawn Not applicable Interventional

Cryotherapy Following Rotator Cuff Repair Surgery

NCT04705376
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Breg Polarcare, Thermazone
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Jul 22, 2026, 9:57 AM EDT
Active, not recruiting No phase listed Observational

Rotator Cuff Failure With Continuity

NCT02716441
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Radio-opaque Tissue Markers
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 22, 2026, 9:57 AM EDT