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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:38 AM EDT

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Showing 121–144 of 171 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Rotator Cuff Tears Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study

NCT03379324
View directory record Official record
Conditions
Rotator Cuff Tear, Fatty Atrophy
Interventions
Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
Biological
Lead sponsor
Applied Biologics, LLC
Industry
Eligibility
Not listed
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 20, 2017 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair

NCT04737980
View directory record Official record
Conditions
Rotator Cuff Tears, Shoulder Pain
Interventions
Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution, Dexamethasone
Drug
Lead sponsor
Hospital for Special Surgery Florida
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears

NCT03295994
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Arthroscopic Rotator Cuff Surgery, Physical Therapy
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 84 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
19
States / cities
Phoenix, Arizona • San Francisco, California • Denver, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Not yet recruiting Not applicable Interventional

H-Wave® Device Stimulation for Post-operative Rotator Cuff Repair Surgery

NCT07501949
View directory record Official record
Conditions
Rotator Cuff Tear Surgical Repair
Interventions
Routine post-surgical care plus H-Wave® Device Stimulation (HWDS), Routine post-surgical care
Device · Other
Lead sponsor
Electronic Waveform Lab
Industry
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Overland Park, Kansas • Kansas City, Missouri • Lee's Summit, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Patient Education and Sling Use After Shoulder Surgery

NCT07851233
View directory record Official record
Conditions
Rotator Cuff Tear, Sling, Shoulder Pain
Interventions
Control - Standard Postoperative Education, Intervention - Living with a Sling Educational Pamphlets
Behavioral
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Phase 3 Interventional

HUPS: Hyalgan Use in Painful Shoulder

NCT00377624
View directory record Official record
Conditions
Osteoarthritis of Shoulder
Interventions
sodium hyaluronate
Drug
Lead sponsor
Sanofi
Industry
Eligibility
35 Years and older
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 11, 2011 · Synced Oct 22, 2026, 4:38 AM EDT
Recruiting Phase 4 Interventional

The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair

NCT07076069
View directory record Official record
Conditions
Rotator Cuff Repairs, Pain Management
Interventions
Multimodal Pain Regimen, Standard of Care Pain Regimen
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Withdrawn Not applicable Interventional

Bone Marrow Derived Stem Cells for the Treatment of Rotator Cuff Tears

NCT03688308
View directory record Official record
Conditions
Rotator Cuff Tear, Rotator Cuff Injury
Interventions
Arthroscopic rotator cuff repair with bone marrow aspirate concentrate, Arthroscopic rotator cuff repair
Procedure
Lead sponsor
Stanford University
Other
Eligibility
50 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 22, 2026, 4:38 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes

NCT06361797
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Rotator cuff repair augmented with whole bone marrow, Rotator cuff repair augmented with concentrated bone marrow
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Columbia, Maryland • Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 22, 2026, 4:38 AM EDT
Not listed No phase listed Observational

An Outcomes Study Utilizing Allomend(R) HD for Superior Capsular Reconstruction

NCT04615117
View directory record Official record
Conditions
Rotator Cuff Tear or Rupture, Not Specified as Traumatic
Interventions
Not listed
Lead sponsor
Western Orthopaedics Research and Education Foundation
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Rotator Cuff Healing Using a Nanofiber Scaffold in Patients Greater Than 55 Years

NCT04325789
View directory record Official record
Conditions
Rotator Cuff Tears, Full-thickness Rotator Cuff Tears
Interventions
nanofiber scaffold
Device
Lead sponsor
Atreon Orthopedics
Industry
Eligibility
55 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
4
States / cities
Fishers, Indiana • Saint Clair Shores, Michigan • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telerehabilitation After Shoulder Arthroplasty

NCT05499728
View directory record Official record
Conditions
Arthritis Shoulder Glenohumoral Joint, Rotator Cuff Tear Arthropathy, Arthropathy Shoulder
Interventions
Telerehabilitation; physical therapy via telecommunication device (i.e. online video conferencing)
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Early Phase 1 Interventional

Rehabilitation: Closed-Chain Exercises for Rotator Cuff Tears

NCT02750176
View directory record Official record
Conditions
Full Thickness Rotator Cuff Tear
Interventions
Closed chain exercises
Other
Lead sponsor
University of Southern California
Other
Eligibility
40 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Oct 22, 2026, 4:38 AM EDT
Enrolling by invitation No phase listed Observational

Reverse Shoulder Arthroplasty vs Rotator Cuff Repair for 60+

NCT06848023
View directory record Official record
Conditions
Shoulder Injuries, Shoulder Pain
Interventions
Reverse Total Shoulder Arthroplasty, Rotator Cuff Repair
Procedure
Lead sponsor
Campbell Clinic
Other
Eligibility
60 Years to 95 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Germantown, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Recruiting No phase listed Observational

Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

NCT04831164
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
NA (not an interventional study)
Other
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 85 Years
Enrollment
3,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
10
States / cities
Iowa City, Iowa • Boston, Massachusetts • Ann Arbor, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial

NCT04115644
View directory record Official record
Conditions
Full Thickness Rotator Cuff Tear, Rotator Cuff Tendinitis
Interventions
Ketorolac, Marcaine (placebo), Kenalog
Drug
Lead sponsor
Michael Khazzam
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
2
States / cities
Baltimore, Maryland • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Comparing the Outcomes Between Rotator Cuff Repair With and Without Suprascapular Nerve Decompression

NCT02107573
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Rotator Cuff Repair without Suprascapular Nerve decompression, Rotator Cuff Repair with Suprascapular Nerve decompression
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2025 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Regenexx™ SD Versus Exercise Therapy for Rotator Cuff Tears

NCT01788683
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Regenexx SD, Exercise Therapy
Procedure · Other
Lead sponsor
Regenexx, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Broomfield, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Oct 22, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional

RSA Vs RCR for Massive RCTs

NCT05807854
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Arthroscopy, Reverse Shoulder Arthroplasty
Procedure · Device
Lead sponsor
La Tour Hospital
Other
Eligibility
60 Years to 80 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 26, 2024 · Synced Oct 22, 2026, 4:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Easytech Reversed Shoulder System Clinical Study

NCT03806842
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus, Rotator Cuff Tear
Interventions
Easytech group
Device
Lead sponsor
FX Shoulder Solutions
Industry
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
6
States / cities
Sun City West, Arizona • Menlo Park, California • Philadelphia, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 22, 2026, 4:38 AM EDT
Not listed Not applicable Interventional

SMR Stemless Reverse Vs SMR Reverse Shoulder System

NCT04697004
View directory record Official record
Conditions
Arthroplasty, Replacement
Interventions
Investigational Arm: SMR Stemless Reverse, Control Arm: SMR Reverse Shoulder System
Device
Lead sponsor
Limacorporate S.p.a
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
11
States / cities
Los Angeles, California • Denver, Colorado • Boca Raton, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Oct 22, 2026, 4:38 AM EDT
Completed Phase 1 Interventional

Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity Using Advanced Imaging Modality Arthroscopy

NCT04340752
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Indocyanine Green
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 22, 2026, 4:38 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries

NCT04793022
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Orthopedic Disorder, Sports Injury, Anesthesia
Interventions
TIVA with Propofol, Inhaled Anesthesia
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 22, 2026, 4:38 AM EDT
Recruiting Phase 4 Interventional

Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation

NCT06289686
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Surgery
Interventions
Rotator cuff repairs with BioEnthesis augmentation, Rotator cuff repairs without BioEnthesis augmentation
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
5
States / cities
Air Force Academy, Colorado • Bethesda, Maryland • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 22, 2026, 4:38 AM EDT