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ClinicalTrials.gov public records Last synced Oct 9, 2026, 4:30 AM EDT

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Showing 25–48 of 201 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Roux-en Y Gastric Bypass Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Ghrelin and Insulin Resistance

NCT00884494
View directory record Official record
Conditions
Obesity, Insulin Resistance, Normal Weight,Healthy Controls
Interventions
Ghrelin infusion to assess effects on insulin sensitivity
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 20, 2017 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Not applicable Interventional Results available

Study of the Effect of the Drug Gabapentin on Postoperative Pain and Incidence of Postoperative Nausea and Vomiting

NCT00886236
View directory record Official record
Conditions
Obesity, Morbid, Postoperative Pain, Postoperative Nausea and Vomiting
Interventions
Gabapentin, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 20, 2018 · Synced Oct 9, 2026, 4:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Determine Incidence of Hypoventilation in Patients Who Have Undergone Gastric Bypass

NCT00316446
View directory record Official record
Conditions
Morbid Obesity, Bariatric Surgery
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 20, 2012 · Synced Oct 9, 2026, 4:30 AM EDT
Enrolling by invitation No phase listed Observational

Endoscopic Metabolic and Bariatric Therapies

NCT05725967
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate, Fistula, Gastric, Roux-en-y Anastomosis Site, Ulcer, Gastric, Abdominal Pain, Abdominal Obesity, Complication of Surgical Procedure, Complication of Treatment, Complication,Postoperative, Weight Gain, Weight Loss, Leak, Anastomotic, Delayed Gastric Emptying Following Procedure
Interventions
Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures, Endoscopic Sleeve Gastroplasty, Trans-oral Outlet Reduction, Intragastric Balloon, Primary obesity surgery endoluminal, Restorative obesity surgery endoluminal, Argon Plasma Coagulation, Gastroplasty with Endoscopic Myotomy, Bariatric Endoscopic Antral Myotomy, Pylorus Sparing Antral Myotomy, Aspiration Therapy
Procedure · Device
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years to 80 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Phase 4 Interventional

A Trial of the Cost Effectiveness of IV Acetaminophen in Bariatric Surgery

NCT02233400
View directory record Official record
Conditions
Hospital Costs, Length of Stay, Postoperative Pain Score, Patient Satisfaction
Interventions
Acetaminophen
Drug
Lead sponsor
St. Luke's Hospital and Health Network, Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Allentown, Pennsylvania • Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2014 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Not applicable Interventional

Bariatric Surgery And Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus

NCT01882036
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Insulin Resistance
Interventions
Gastric Bypass w/ matched hypocaloric diet, Hypocaloric diet
Procedure · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 9, 2026, 4:30 AM EDT
Completed No phase listed Observational

Endotoxin and Intestinal Flora Before and After Gastric Bypass or Banding in Diabetics

NCT00960765
View directory record Official record
Conditions
Obesity, Morbid, Diabetes Mellitus, Type 2, Gastric Bypass
Interventions
Not listed
Lead sponsor
CPL Associates
Other
Eligibility
18 Years to 95 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Buffalo, New York • Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Oct 9, 2026, 4:30 AM EDT
Completed No phase listed Observational

Wound Repair and Body Contouring Surgery After Gastric Bypass

NCT00609037
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 9, 2026, 4:30 AM EDT
Completed No phase listed Observational

Roux-en-Y Gastric Bypass and Weight Regain

NCT02302898
View directory record Official record
Conditions
Obesity
Interventions
Eating Behavior Evaluation, Measurement of Functional gastric volume, Measurement of gastric pouch and GJ size
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Phase 3 Interventional

Surgery Or Lifestyle Intervention for Type 2 Diabetes (SOLID)

NCT01040468
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y Gastric Bypass surgery, Laparoscopic Adjustable Gastric Banding surgery, Intensive Lifestyle Modification
Procedure · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2016 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Preliminary Comparison of the Blood Levels of Medications in Obese Subjects Compared to Post-Gastric Bypass Subjects

NCT01015976
View directory record Official record
Conditions
Obesity
Interventions
bariatric surgery, control
Procedure · Other
Lead sponsor
Neuropsychiatric Research Institute, Fargo, North Dakota
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion

NCT00587041
View directory record Official record
Conditions
Nephrolithiasis, Hyperoxaluria, Crohn's Disease
Interventions
Oxadrop, Agri-King Synbiotic (AKSB), Placebo
Dietary Supplement · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Not applicable Interventional

Effect of Number of Meals on Metabolism After Weight Loss Surgery

NCT02929212
View directory record Official record
Conditions
Morbid Obesity
Interventions
Solid Meal, Liquid Meal, Acetaminophen, Single, 600 kcal meal, Multiple, 200 kcal meals
Other · Drug
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 9, 2026, 4:30 AM EDT
Completed No phase listed Observational

Laparoscopic Revision Gastric Bypass for Weight Recidivism

NCT01040572
View directory record Official record
Conditions
Weight Regain, Weight Recidivism, Obesity Recidivism, Clinically Severe Obesity
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Dec 29, 2009 · Synced Oct 9, 2026, 4:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Bariatric Surgery on Insulin

NCT00535600
View directory record Official record
Conditions
Obesity, Bariatric Surgery, Gastric Bypass, Weight Loss, Hyperglycemia
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 96 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effects of Gastric Bypass on Blood Levels of Duloxetine

NCT00989157
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Duloxetine
Drug
Lead sponsor
Neuropsychiatric Research Institute, Fargo, North Dakota
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 11, 2014 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Not applicable Interventional

Post-Gastric Bypass Hypoglycemia

NCT01933490
View directory record Official record
Conditions
Hyperinsulinemic Hypoglycemia
Interventions
high carbohydrate test meal, high carbohydrate test meal after pre-treatment with rapid acting aspart insulin, high fructose , low glucose test meal with carbohydrate and caloric content similar to the control meal
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 9, 2026, 4:30 AM EDT
Completed No phase listed Observational Results available

Taste Perception Pre and Post Bariatric Surgery

NCT01536197
View directory record Official record
Conditions
Morbid Obesity
Interventions
Gastric bypass, Gastric banding, Sleeve gastrectomy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Endostapled Anastomoses for Laparoscopic Gastric Bypass (EEA-LGB)

NCT00254072
View directory record Official record
Conditions
Morbid Obesity
Interventions
3.5 mm vs 4.8 mm Stapler During Laparoscopic Gastric Bypass
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 60 Years
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Orange, California • Tampa, Florida • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2010 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Early Phase 1 Interventional

The Contribution of Incretin Hormones to the Amelioration of Glucose Metabolism After Roux-en-Y Gastric Bypass

NCT01843855
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Exendin 9,39, Placebo
Drug
Lead sponsor
Adrian Vella
Other
Eligibility
20 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 4, 2013 · Synced Oct 9, 2026, 4:30 AM EDT
Withdrawn No phase listed Observational

Bariatric Surgery Outcomes

NCT01057784
View directory record Official record
Conditions
Morbid Obesity
Interventions
Bariatric surgery.
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation Effects on Pain Perception

NCT01861574
View directory record Official record
Conditions
Gastric Bypass Surgery Pain Management
Interventions
Real TMS 45 min, Sham TMS 45 min, Real TMS 4 Hours, Sham TMS 4 Hours
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 9, 2026, 4:30 AM EDT
Recruiting Not applicable Interventional

Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery

NCT05838300
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Warm humidified CO2, Dry CO2
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 9, 2026, 4:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes

NCT01786941
View directory record Official record
Conditions
Branched-chain Amino Acid Metabolism, Insulin Sensitivity
Interventions
Pre-Diabetes Group - 6-mo Aerobic and Resistance combined exercise training, GBP Group - Non-diabetics intending to undergo Gastric Bypass surgery
Other
Lead sponsor
Duke University
Other
Eligibility
30 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced Oct 9, 2026, 4:30 AM EDT