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ClinicalTrials.gov public records Last synced May 22, 2026, 4:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Rupture Clear all
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Rupture of Anterior Cruciate Ligament
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
10 Years to 80 Years
Enrollment
3,294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2028
U.S. locations
8
States / cities
Boulder, Colorado • Iowa City, Iowa • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced May 22, 2026, 4:46 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available
View directory record Official record
Conditions
Dry Eye
Interventions
RPS InflammaDry Detector™
Device
Lead sponsor
Rapid Pathogen Screening
Industry
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
8
States / cities
Bradenton, Florida • Miami, Florida • Springfield, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2022 · Synced May 22, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Premature Rupture of Membranes
Interventions
Foley Catheter, Oxytocin
Device · Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
Female only
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
5
States / cities
Phoenix, Arizona • Newark, Delaware • Allentown, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced May 22, 2026, 4:46 AM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Post Term Pregnancy, Premature Rupture of Membrane, Fetal Growth Retardation, Oligohydramnios, Gestational Diabetes, High Blood Pressure in Pregnancy
Interventions
Dilapan-S
Device
Lead sponsor
Medicem Technology s.r.o.
Other
Eligibility
18 Years and older · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced May 22, 2026, 4:46 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Rotator Cuff Injury
Interventions
Suture Anchor HEALOCOIL, Suture anchor Twinfix Ultra HA
Device
Lead sponsor
The Hawkins Foundation
Other
Eligibility
35 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced May 22, 2026, 4:46 AM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Rupture of Anterior Cruciate Ligament
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
12 Years to 65 Years
Enrollment
1,234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2029
U.S. locations
47
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 39 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced May 22, 2026, 4:46 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Rotator Cuff Tear, Rotator Cuff Tears, Rotator Cuff Tears of the Shoulder
Interventions
FiberLocker® System (encompassing FiberLocker® Instrument SN & SpeedPatch® PET)
Device
Lead sponsor
ZuriMED Technologies Inc.
Industry
Eligibility
30 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Chicago, Illinois • Columbia, Maryland • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2025 · Synced May 22, 2026, 4:46 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
Interventions
Not listed
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced May 22, 2026, 4:46 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Juxtarenal Aortic Aneurysm, Aortic Rupture
Interventions
Implantation of Physician-Modified Terumo Aortic TREO abdominal stent graft system
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced May 22, 2026, 4:46 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Aortic Dissection
Interventions
Endovascular Treatment (Zenith)
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
23
States / cities
Los Angeles, California • Gainesville, Florida • Tampa, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced May 22, 2026, 4:46 AM EDT
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Cataract
Interventions
Systane Complete
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced May 22, 2026, 4:46 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Rotator Cuff Tears of the Shoulder
Interventions
Integrity Implant System
Device
Lead sponsor
Anika Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Tampa, Florida • Fishers, Indiana • Towson, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced May 22, 2026, 4:46 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Observational Cohort
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
45 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
4
States / cities
Boston, Massachusetts • Sioux Falls, South Dakota • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced May 22, 2026, 4:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Meniscal Degeneration, Osteoarthritis, Knee
Interventions
TeMPO Home Exercise Program, Motivational SMS Messages, In-Clinic Topical Therapy, In-Clinic Exercise Therapy
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years to 85 Years
Enrollment
879 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
Boston, Massachusetts • Buffalo, New York • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced May 22, 2026, 4:46 AM EDT
Recruiting Phase 4 Interventional
View directory record Official record
Conditions
Ocular Surface Disease, Neurotrophic Keratopathy Stage 1
Interventions
Patients will receive topical Acoltremon 0.003% ophthalmic solution BID in both eyes over an 8 week period., Alternative would be patient exiting the trial and starting on tears or other standard of care.
Drug · Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced May 22, 2026, 4:46 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Dry Eye Syndrome, Keratoconjunctivitis Sicca
Interventions
Oculeve Intranasal Neurostimulator
Device
Lead sponsor
Oculeve, Inc.
Industry
Eligibility
22 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Artesia, California • Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced May 22, 2026, 4:46 AM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
ACL Tear
Interventions
Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
Device · Other
Lead sponsor
Candice Dunkin, MS, LAT, ATC
Other
Eligibility
16 Years to 22 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced May 22, 2026, 4:46 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Preterm Premature Rupture of Membrane, Amniotic Fluid Leakage
Interventions
Ferning on microscopy
Diagnostic Test
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced May 22, 2026, 4:46 AM EDT
Withdrawn Phase 2 Interventional
View directory record Official record
Conditions
ACL - Anterior Cruciate Ligament Rupture, ACL Injury
Interventions
Platelet Rich Plasma, Saline Placebo
Biological · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced May 22, 2026, 4:46 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Childbirth
Interventions
Materna Prep Device, Sham Control
Device
Lead sponsor
Materna Medical
Industry
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced May 22, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions
Exercise Group
Other
Lead sponsor
Johanna M. Hoch
Other
Eligibility
18 Years to 35 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced May 22, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Contact Lens Solutions
Interventions
Opti-Free® RepleniSH® MPDS, ReNu MultiPlus®
Device
Lead sponsor
Manhattan Vision Associates
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2013 · Synced May 22, 2026, 4:46 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Arthroplasty, Replacement
Interventions
Investigational Arm: SMR Stemless Reverse, Control Arm: SMR Reverse Shoulder System
Device
Lead sponsor
Limacorporate S.p.a
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
11
States / cities
Los Angeles, California • Denver, Colorado • Boca Raton, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced May 22, 2026, 4:46 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Preterm Premature Rupture of Membranes
Interventions
Magnesium sulfate
Drug
Lead sponsor
Regional Obstetrical Consultants
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced May 22, 2026, 4:46 AM EDT