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ClinicalTrials.gov public records Last synced Sep 11, 2026, 4:14 PM EDT

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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ruptured Aneurysm Clear all
Recruiting Not applicable Interventional

Physician Modified Endovascular Grafts

NCT01538056
View directory record Official record
Conditions
Abdominal Aortic Aneurysms
Interventions
Fenestrated Endovascular Graft or Company Manufactured Terumo Aortic Fenestrated TREO Endovascular Graft
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2055
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 11, 2026, 4:14 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2 (iSPASM-2)

NCT07493577
View directory record Official record
Conditions
Aneurysmal Subarachnoid Hemorrhage
Interventions
Tirofiban, Placebo
Drug
Lead sponsor
Dr David Hasan, M.D.
Other
Eligibility
18 Years to 85 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Durham, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 11, 2026, 4:14 PM EDT
Completed Phase 1Phase 2 Interventional

Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage

NCT01893190
View directory record Official record
Conditions
Ruptured Cerebral Aneurysm, Ruptured Berry Aneurysm
Interventions
Nimodipine, Nimodipine Microparticles
Drug
Lead sponsor
Edge Therapeutics Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
16
States / cities
Phoenix, Arizona • Los Angeles, California • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 11, 2026, 4:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Surgical Theater's Surgery Rehearsal Platform

NCT02099318
View directory record Official record
Conditions
Cerebral Aneurysm Unruptured, Cerebral Aneurysm Ruptured
Interventions
Active SRP cases, Control cases
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Sep 11, 2026, 4:14 PM EDT
Not listed No phase listed Observational

Aneurysm Genetic Risk in Patients With QIB Changes

NCT05317169
View directory record Official record
Conditions
Brain Aneurysm
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Sep 11, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Treatment of Brain AVMs (TOBAS) Study

NCT02098252
View directory record Official record
Conditions
Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation, Arteriovenous Malformations, AVM, BAVM
Interventions
Neurosurgery, Radiation therapy, Embolization
Procedure · Radiation
Lead sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Other
Eligibility
5 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2036
U.S. locations
3
States / cities
Jacksonville, Florida • Boston, Massachusetts • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Sep 11, 2026, 4:14 PM EDT
Active, not recruiting Not applicable Interventional

Early Feasibility Study of the RelayBranch Thoracic Stent-Graft System

NCT03214601
View directory record Official record
Conditions
Thoracic Aorta Aneurysm, Aneurysm, Ruptured, Aortic Aneurysm
Interventions
penetrating atherosclerotic ulcer, aorta branch cardiovascular implant
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
12
States / cities
Los Angeles, California • Gainesville, Florida • Atlanta, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 11, 2026, 4:14 PM EDT
Not listed No phase listed Observational

Ruptured Aneurysms Treated With Hydrogel Coils

NCT03252314
View directory record Official record
Conditions
Ruptured Aneurysm
Interventions
Second-generation hydrogel coils
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 11, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Complex Aortic Aneurysms

NCT06834607
View directory record Official record
Conditions
Juxta Renal Abdominal Aortic Aneurysm Without Rupture, Complex Aortic Aneurysms, Aortic Aneurysm
Interventions
Physician Modified Aortic Endograft repair for complex aortic aneurysm
Device
Lead sponsor
Akhilesh Jain
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 11, 2026, 4:14 PM EDT
Not listed Not applicable Interventional

Appraising the Embolization of Aneurysms Using Balt Optima™ Coil System (APPLY Study)

NCT04499508
View directory record Official record
Conditions
Aneurysm, Intracranial Aneurysm, Ruptured Aneurysm, Subarachnoid Hemorrhage, Aneurysmal, Cerebral Aneurysm Unruptured
Interventions
Optima Coil System
Device
Lead sponsor
Vascular Neurology of Southern California Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Thousand Oaks, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Sep 11, 2026, 4:14 PM EDT
Withdrawn Phase 2 Interventional

Safety and Efficacy Study of a Single Dose of NA-1 in Patients Undergoing Endovascular Repair of Ruptured Aneurysms

NCT02056574
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Ruptured Intracranial Aneurysm
Interventions
NA-1, Placebo
Drug
Lead sponsor
NoNO Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
5
States / cities
Phoenix, Arizona • Englewood, Colorado • Ann Arbor, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 11, 2026, 4:14 PM EDT
Terminated Phase 3 Interventional

Study of EG-1962 Compared to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage

NCT02790632
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
EG-1962 (nimodipine microparticles), Enteral Nimodipine
Drug
Lead sponsor
Edge Therapeutics Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
45
States / cities
Birmingham, Alabama • Phoenix, Arizona • Fresno, California + 32 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 11, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms

NCT07019454
View directory record Official record
Conditions
Technical Sucess, Freedom From Type I and III Endoleaks at 12 Months, Freedom From Stent Graft Migration at 12 Months, Freedom From Aortic Aneurysm Enlargement at 12 Months, Freedom From Aortic Aneurysm Rupture or Conversion to Open Repair at 12 Months
Interventions
Physician Modified Endografting
Device
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2035
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 11, 2026, 4:14 PM EDT
Not listed Not applicable Interventional

International Subarachnoid Aneurysm Trial II

NCT01668563
View directory record Official record
Conditions
Intracranial Hemorrhage Ruptured Aneurysm
Interventions
surgical management, Endovascular management
Procedure
Lead sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Other
Eligibility
18 Years and older
Enrollment
1,724 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Sep 11, 2026, 4:14 PM EDT
Completed No phase listed Observational

Global Impact of the COVID 19 Pandemic on Stroke Care, Cerebral Venous Thrombosis, and Subarachnoid Hemorrhage

NCT04934020
View directory record Official record
Conditions
Stroke
Interventions
Pre-pandemic stroke related metrics, Stroke related metrics during the pandemic
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
345,089 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Atlanta, Georgia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Sep 11, 2026, 4:14 PM EDT
Active, not recruiting Phase 2 Interventional

Minocycline for Aneurysmal Subarachnoid Hemorrhage (MASH)

NCT04876638
View directory record Official record
Conditions
Aneurysm, Ruptured, Vasospasm, Intracranial, Delayed Cerebral Ischemia, Blood Brain Barrier Defect
Interventions
Minocyclin
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 11, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

University of Utah PS-IDE: Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms

NCT07065760
View directory record Official record
Conditions
Juxtarenal Abdominal Aortic Aneurysm
Interventions
Endovascular Aneurysm Repair with Physician Modified Endograft
Device
Lead sponsor
Cali Johnson
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 11, 2026, 4:14 PM EDT
Terminated Phase 1 Interventional

Safety/Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With aSAH

NCT02893826
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
EG-1962 (nimodipine microparticles), Enteral Nimodipine
Drug
Lead sponsor
Edge Therapeutics Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Phoenix, Arizona • San Francisco, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 11, 2026, 4:14 PM EDT
Terminated Not applicable Interventional Results available

Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients

NCT02864940
View directory record Official record
Conditions
Ruptured Aneurysm, Memory Deficits, Subarachnoid Hemorrhage
Interventions
Lumosity, Crossword puzzle
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 9, 2023 · Synced Sep 11, 2026, 4:14 PM EDT
Terminated Not applicable Interventional

EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms With the Pipeline™ Flex Embolization Device With Shield TEchnology™ (ELEVATE)

NCT04391803
View directory record Official record
Conditions
Intracranial Aneurysm, Ruptured Aneurysm
Interventions
Pipeline™ Flex Embolization Device with Shield Technology™
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
7
States / cities
New Haven, Connecticut • Marietta, Georgia • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 11, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Physician Modified Endovascular Grafts for the Treatment of Juxtarenal Aortic Aneurysms

NCT06657794
View directory record Official record
Conditions
Juxtarenal Aortic Aneurysm, Aortic Rupture
Interventions
Implantation of Physician-Modified Terumo Aortic TREO abdominal stent graft system
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 11, 2026, 4:14 PM EDT
Recruiting No phase listed Observational

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

NCT04937868
View directory record Official record
Conditions
Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury, Hip Injuries, Liver Injury, Spleen Injury, Renal Injury, Diaphragm Injury, Aortic Rupture, Aortic Dissection, Bowel Disease, Vascular System Injuries, Sacral Fracture
Interventions
There are no interventions associated with this study
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
12,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 11, 2026, 4:14 PM EDT
Active, not recruiting Not applicable Interventional

A Medical Device to Treat Wide-Neck Brain Aneurysms

NCT05550571
View directory record Official record
Conditions
Ruptured Cerebral Aneurysm
Interventions
Nautilus Intrasaccular Bridging System
Device
Lead sponsor
EndoStream Medical
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Jacksonville, Florida • Tampa, Florida • Buffalo, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 11, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

NCT05103566
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
gammaCore
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 11, 2026, 4:14 PM EDT