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ClinicalTrials.gov public records Last synced Sep 4, 2026, 12:39 PM EDT

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Showing 1–24 of 86 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Male Infertility
Interventions
Andrositol® Test
Diagnostic Test
Lead sponsor
Lo.Li.Pharma s.r.l
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pasadena, California
Conditions
Infertility, Male
Interventions
Ejaculatory abstinence less than 24 hours
Diagnostic Test
Lead sponsor
Boston IVF
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Waltham, Massachusetts
Conditions
Spermatogenesis and Semen Disorders, Infertility, Male
Interventions
Power Prenatal for Sperm
Dietary Supplement
Lead sponsor
The Bird and Be Co Inc
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Encino, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Project 1: Diet and Exercise Modulate the Sperm Epigenome in Men

NCT04175678
Conditions
Healthy Lifestyle, Obese, Men
Interventions
Diet, Exercise, Standard care
Other
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Torrance, California
Conditions
Acute Scrotum, Testicular Torsion
Interventions
Hutchison Technologies Inspectra StO2 SpotCheck Near-Infrared Spectroscopy
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
1 Month to 21 Years · Male only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Withdrawn Phase 2Phase 3 Interventional

Androxal in Male Infertility

NCT02160704
Conditions
Infertility
Interventions
Enclomiphene citrate, Placebo
Drug · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 35 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Conditions
Male Infertility, Azoospermia
Interventions
BAIBYS Sperm selection, Intra cytoplasmatic sperm injection, Conventional manual sperm selection
Device · Procedure
Lead sponsor
BAIBYS Fertility
Industry
Eligibility
21 Years to 42 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Stamford, Connecticut
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

NCT03860558
Conditions
Overweight, Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Interventions
Lifestyle Intervention, No Intervention
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Infertility, Recurrent Pregnancy Loss
Interventions
Microfluidics chamber, Density Gradient Centrifugation
Device · Other
Lead sponsor
Lawrence Engmann
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Farmington, Connecticut
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Impact of Escitalopram on Sperm DNA Fragmentation

NCT03527043
Conditions
Sperm DNA Fragmentation, Infertility, Male
Interventions
Escitalopram, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Brain and Central Nervous System Tumors, Chemotherapeutic Agent Toxicity, Infertility
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Infertility, Infertility, Male
Interventions
Ohana IVF Sperm Preparation Kit (OHB035), Standard IVF Preparation Kit (OHB037)
Device
Lead sponsor
Ohana BioSciences
Industry
Eligibility
25 Years to 37 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
7
States / cities
Tempe, Arizona • Clearwater, Florida • Rockville, Maryland + 4 more
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Ramipril for the Treatment of Oligospermia

NCT01856361
Conditions
Oligospermia, Teratospermia, Asthenozoospermia, Male Infertility
Interventions
Ramipril, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Conditions
DNA Damage, DNA Strand Breaks, Sperm DNA Fragmentation
Interventions
sperm separation device
Device
Lead sponsor
Richard Kordus, PhD, HCLD (ABB)
Other
Eligibility
18 Years to 34 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, South Carolina
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of New Semen Collection & Transportation Kit

NCT04536545
Conditions
Sperm Parameters in Fertile and Infertile Men
Interventions
Not listed
Lead sponsor
Turtle Health, Inc.
Industry
Eligibility
Male only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Erectile Dysfunction
Interventions
Levitra (Vardenafil, BAY38-9456), Sildenafil, Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
25 Years to 64 Years · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
18
States / cities
Phoenix, Arizona • Tempe, Arizona • Beverly Hills, California + 15 more
Conditions
Cancer
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
13 Years to 21 Years · Male only
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Duarte, California • Los Angeles, California • Atlanta, Georgia + 5 more
Conditions
Infertility
Interventions
SpermComet assay
Other
Lead sponsor
Bruce Shapiro M.D.
Industry
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Conditions
Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
Interventions
Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rockville, Maryland
Terminated Not applicable Interventional

Fresh Vs Frozen Surgical Sperm in IVF

NCT03361982
Conditions
Infertility
Interventions
Slow Freezing and Thawing
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
Not listed
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Terminated Not applicable Interventional Results available

Effectiveness of Celecoxib After Surgical Sperm Retrieval

NCT01323595
Conditions
Pain
Interventions
Celecoxib, Sugar Pill
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Azoospermia, Nonobstructive, Infertility, Male
Interventions
Ultrasound-guided rete testis flushing and aspiration
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Different Ingestion Doses of Celastrol on Human Sperm Motility

NCT05413226
Conditions
Safety Issues
Interventions
Celastrol
Dietary Supplement
Lead sponsor
Legend Labz, Inc.
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
HIV-1, Fertility, Infertility
Interventions
Sperm Washing with Intrauterine Insemination (IUI)
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts