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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: SPINAL Fracture Clear all
Terminated Not applicable Interventional Results available

Dynesys Spinal System Post Market 522 Study

NCT01528072
View directory record Official record
Conditions
Degenerative Spondylolisthesis, Pseudoarthrosis
Interventions
Dynesys Spinal System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years to 80 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
9
States / cities
Belleville, Illinois • Baltimore, Maryland • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of Vertebral Fracture Risk for First Time Liver Transplant Candidates

NCT03811873
View directory record Official record
Conditions
Metabolic Bone Disease, Transplant-Related Disorder, Secondary Osteoporosis
Interventions
Dual x-ray absorptiometry, Vertebral Fracture Assessment
Diagnostic Test · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Phase 3 Interventional Results available

Effect of Teriparatide Compared to Risedronate on Back Pain in Women With a Spine Fracture Caused by Osteoporosis

NCT00343252
View directory record Official record
Conditions
Osteoporosis, Postmenopausal, Back Pain, Spinal Fracture
Interventions
teriparatide, risedronate, placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older · Female only
Enrollment
712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
20
States / cities
Birmingham, Alabama • Montgomery, Alabama • Peoria, Arizona + 17 more
Source: ClinicalTrials.gov public record
Updated May 25, 2011 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Phase 4 Interventional Results available

VERtebral Fracture Treatment Comparisons in Osteoporotic Women

NCT01709110
View directory record Official record
Conditions
Postmenopausal Osteoporosis
Interventions
Teriparatide, Risedronate, Placebo, Calcium, Vitamin D
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older · Female only
Enrollment
1,366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
30
States / cities
Birmingham, Alabama • Concord, California • Fresno, California + 27 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2019 · Synced Jul 22, 2026, 2:27 PM EDT
Active, not recruiting Not applicable Interventional Results available

Sickle Cell Disease (SCD) Bone Pain Study

NCT05283148
View directory record Official record
Conditions
Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis, Osteopenia, Vertebral Fracture, Vertebral Compression, Osteonecrosis, Ischemic Necrosis, Avascular Necrosis
Interventions
Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Jul 22, 2026, 2:27 PM EDT
Not listed Not applicable Interventional

Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study

NCT03911492
View directory record Official record
Conditions
Acute Spinal Cord Injury, Acute Spinal Paralysis, Spinal Cord Injuries, SPINAL Fracture
Interventions
SCPP Management => 65 mmHg
Procedure
Lead sponsor
University of British Columbia
Other
Eligibility
17 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
San Francisco, California • Omaha, Nebraska • Albuquerque, New Mexico + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jul 22, 2026, 2:27 PM EDT
Withdrawn Phase 4 Interventional

GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture

NCT03226080
View directory record Official record
Conditions
Hip Fractures, Anesthesia, Spinal, Anesthesia, General, Neuromuscular Blockade
Interventions
Rocuronium, Sugammadex, Normal saline
Drug
Lead sponsor
Loyola University
Other
Eligibility
55 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Jul 22, 2026, 2:27 PM EDT
Terminated Not applicable Interventional Results available

Vertebral Augmentation and Radiotherapy of Collapse Spinal Metastatic Cancer

NCT02376933
View directory record Official record
Conditions
Metastatic Cancers, Multiple Myeloma, Vertebral Fracture
Interventions
Vertebroplasty, Radiotherapy
Procedure · Radiation
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Jul 22, 2026, 2:27 PM EDT
Withdrawn Not applicable Interventional

Evaluation of Fracture Fixation With Energy and Cement in Tumors of the Spine

NCT00594321
View directory record Official record
Conditions
Spinal Fractures
Interventions
SPACE CpsXL Bone Cement and SPACE 360 Delivery System, standard vertebroplasty
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2012 · Synced Jul 22, 2026, 2:27 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

OsseoFix™ Spinal Fracture Reduction System in Treating Spinal Compression Fracture

NCT00961714
View directory record Official record
Conditions
Vertebral Compression Fractures
Interventions
OsseoFix Spinal Fracture Reduction System
Device
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
50 Years to 105 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
11
States / cities
La Jolla, California • Boulder, Colorado • Littleton, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Jul 22, 2026, 2:27 PM EDT
Active, not recruiting Not applicable Interventional

Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System

NCT03626038
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Psoriatic Arthritis, Proximal Humeral Fracture
Interventions
A.L.P.S. Proximal Humerus Plating System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Three Instructional Interventions for Prehospital Cervical Spinal Immobilization by Laypeople

NCT05359575
View directory record Official record
Conditions
Cervical Vertebra Injury, Cervical Vertebra Fracture
Interventions
Audio kit, Instructional flashcard (version 1), In-person training, Instructional flashcard (version 2)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
265 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Not applicable Interventional

To Evaluate Success of Cement Treatment of Spinal Compression Fractures

NCT00166374
View directory record Official record
Conditions
Back Pain
Interventions
balloon kyphoplasty
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2010 · Synced Jul 22, 2026, 2:27 PM EDT
Not listed No phase listed Observational

Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

NCT05608460
View directory record Official record
Conditions
Cervical Spine Fracture
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
0 Years to 17 Years
Enrollment
15,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • San Diego, California + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Jul 22, 2026, 2:27 PM EDT
Not listed Not applicable Interventional

Intra-operative Assessment of the Intellirod LOADPRO Spinal Rod Strain Sensor for Use During Kyphotic Corrective Surgery

NCT02768675
View directory record Official record
Conditions
Kyphosis, Spinal Fractures
Interventions
LOADPRO
Device
Lead sponsor
Intellirod Spine
Industry
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Louisville, Kentucky • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Jul 22, 2026, 2:27 PM EDT
Withdrawn Not applicable Interventional

Randomized Trial With an Observational Component of Non-operative Versus Operative Treatment for AO Type A3 Fractures

NCT02179697
View directory record Official record
Conditions
Spinal Fractures
Interventions
Patient's Choice, Surgery + Bracing vs. Bracing Alone
Other · Procedure
Lead sponsor
H Francis Farhadi
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 17, 2017 · Synced Jul 22, 2026, 2:27 PM EDT
Recruiting No phase listed Observational

Gait and Bone Health in SMA

NCT07400198
View directory record Official record
Conditions
Spinal Muscular Atrophy Type 3, Ambulatory Spinal Muscular Atrophy
Interventions
Not listed
Lead sponsor
Jacqueline Montes
Other
Eligibility
8 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Early Phase 1 Interventional

Basivertebral Nerve Block During Vertebral Augmentation: An Alternative Approach to Intraprocedural Pain Management

NCT04774029
View directory record Official record
Conditions
Vertebral Compression, Vertebra Compression Fracture, Vertebral Fracture
Interventions
Basivertebral nerve block, Lidocaine induced basivertebral nerve block
Procedure · Drug
Lead sponsor
Northwell Health
Other
Eligibility
50 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Port Jefferson, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2021 · Synced Jul 22, 2026, 2:27 PM EDT
Completed No phase listed Observational

Health-Related Quality of Life (QOL), Physical and Respiratory Function in Patients With Myeloma Affecting the Spine

NCT01006070
View directory record Official record
Conditions
Multiple Myeloma
Interventions
kyphoplasty
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2012 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Phase 4 Interventional Results available

BIO4 Clinical Case Study: Cervical Spine

NCT03077204
View directory record Official record
Conditions
Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
Interventions
1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
Biological · Device
Lead sponsor
Seton Healthcare Family
Other
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Not applicable Interventional

Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients

NCT00933036
View directory record Official record
Conditions
Pathologic Fracture of the Vertebra Due to Osteoporosis
Interventions
Crosstrees Pod system for PVA
Device
Lead sponsor
Crosstrees Medical Inc.
Industry
Eligibility
50 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
9
States / cities
Long Beach, California • Washington D.C., District of Columbia • Clearwater, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2014 · Synced Jul 22, 2026, 2:27 PM EDT
Completed No phase listed Observational

Bone MicroArchitecture in Acromegaly

NCT03225040
View directory record Official record
Conditions
Acromegaly, Osteoporosis Risk
Interventions
Pegvisomant
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Phase 3 Interventional Results available

The Kiva® System as a Vertebral Augmentation Treatment

NCT01123512
View directory record Official record
Conditions
Spinal Fractures, Fractures, Compression, Back Injuries
Interventions
Vertebral augmentation
Device
Lead sponsor
Benvenue Medical, Inc.
Industry
Eligibility
50 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
15
States / cities
Encinitas, California • Mountain View, California • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2014 · Synced Jul 22, 2026, 2:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Relationship Between Irisin and Bone Health in Individuals With Spinal Cord Injury

NCT05319522
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Acute Exercise
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jul 22, 2026, 2:27 PM EDT