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Showing 1–24 of 517 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: STI Prevention Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Lay Health Advisors for Sexually Transmitted Disease Prevention

NCT00207506
View directory record Official record
Conditions
Syphilis, Gonorrhea, Chlamydia Infections, HIV Infections
Interventions
HoMBReS: A lay health advisor approach to STD prevention
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
354 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2012 · Synced Sep 4, 2026, 9:24 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Joining Under-connected Networks to Optimize "Salud" (Health) ("JUNTOS")

NCT06432725
View directory record Official record
Conditions
Hiv
Interventions
JUNTOS, Referral Sheet
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 4, 2026, 9:24 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Video-Based Delivery of HIV Test Information for Spanish-Speaking Latinos

NCT01452555
View directory record Official record
Conditions
HIV, AIDS
Interventions
Video or In-Person Presentation
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 16, 2011 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 3 Interventional

A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients

NCT00000991
View directory record Official record
Conditions
Pneumonia, Pneumocystis Carinii, HIV Infections
Interventions
Pentamidine isethionate, Sulfamethoxazole-Trimethoprim, Dapsone, Zidovudine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1994
U.S. locations
20
States / cities
Los Angeles, California • Oakland, California • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 2 Interventional

Improving HIV Prevention Skills in People With Serious Mental Illnesses

NCT00356291
View directory record Official record
Conditions
HIV/AIDS
Interventions
Skill-Building (SB) plus Motivational Interviewing, Skill-Building (SB)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
19 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 24, 2013 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Male Circumcision Services for HIV Prevention in the Dominican Republic

NCT02337179
View directory record Official record
Conditions
Circumcision, Male, HIV, AIDS
Interventions
Voluntary medical male circumcision
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
539 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Sep 4, 2026, 9:24 AM EDT
Completed No phase listed Observational

Prevention and Treatment Continuum for Youth at HIV Risk, Acutely Infected and With Established HIV Infection

NCT03205696
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Antiretrovirals
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Los Angeles, California • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Sep 4, 2026, 9:24 AM EDT
Not yet recruiting Not applicable Interventional

Improving HIV Prevention and Substance Use Post-Sexual Assault Services

NCT07225062
View directory record Official record
Conditions
HIV Infections, Substance Use, Sexual Assault
Interventions
Enhanced intervention, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
17 Years to 25 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Advancing HIV Prevention and Linkage to Care Among MSM With Gamification

NCT02946164
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
Stick To It
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 26 Years · Male only
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Los Angeles, California • Oakland, California
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Training Community Members to Deliver HIV Prevention Programs to Urban Youth

NCT00859144
View directory record Official record
Conditions
HIV, HIV Infections
Interventions
Be Proud! Be Responsible!, Becoming A Responsible Teen (BART), Reducing the Risk
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 60 Years
Enrollment
901 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Sep 4, 2026, 9:24 AM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings

NCT06854029
View directory record Official record
Conditions
HIV Infections, Opioid Use Disorder, Incarceration; Lens
Interventions
Cabotegravir Injection, Cabotegravir Pill, Buprenorphine injection, Buprenorphine Pill
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Not applicable Interventional Results available

Cardiovascular Prevention for Persons With HIV

NCT00982189
View directory record Official record
Conditions
HIV Infection, Cardiovascular Disease Risk
Interventions
Pravastatin, Lisinopril
Drug
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
40 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 21, 2017 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Study Evaluating Implementation Strategies for the Delivery of APRETUDE for Black cis-and Transgender Women in United States EHE Territories

NCT05514509
View directory record Official record
Conditions
HIV Infections
Interventions
APRETUDE, Cabotegravir tablet
Drug
Lead sponsor
ViiV Healthcare
Industry
Eligibility
18 Years and older · Female only
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
22
States / cities
Washington D.C., District of Columbia • Miami, Florida • Orlando, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Adopting and Demonstrating the Adaptation of Prevention Techniques: Community PROMISE PLUS

NCT00267436
View directory record Official record
Conditions
HIV Prevention, STD Prevention
Interventions
Community PROMISE
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
574 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
2
States / cities
Boston, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 12, 2012 · Synced Sep 4, 2026, 9:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Factors Affecting PrEP Adherence

NCT02411630
View directory record Official record
Conditions
HIV Infection
Interventions
Emtricitabine/tenofovir disoproxil
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 22 Years · Male only
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
12
States / cities
Los Angeles, California • Aurora, Colorado • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 3 Interventional

The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients

NCT00001030
View directory record Official record
Conditions
Mycobacterium Avium-intracellulare Infection, HIV Infections
Interventions
Clarithromycin, Rifabutin
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
12 Years and older
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1996
U.S. locations
41
States / cities
Birmingham, Alabama • Los Angeles, California • Oakland, California + 24 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 4, 2026, 9:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The TAIL-PrEP Study

NCT06868641
View directory record Official record
Conditions
HIV Infections
Interventions
TAIL-PrEP for patients discontinuing cab-LA, TAIL-PrEP for patients considering discontinuing cab-LA, TAIL-PrEP for patients considering discontinuing LEN
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 4, 2026, 9:24 AM EDT
Terminated Not applicable Interventional

Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients

NCT00655226
View directory record Official record
Conditions
Hepatitis C, Depressive Disorder, Major, Depressive Disorder, Depression, HIV Infections
Interventions
Hepatitis C educational support groups, Cognitive Behavioral Therapy skills based group sessions
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 8, 2011 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Parents Matter!: Interventions to Promote Effective Parent-Child Communication

NCT00137943
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases, Pregnancy
Interventions
Full Parent communication intervention, Brief Parent Communication Intervention, Control Parent Intervention
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
9 Years to 12 Years
Enrollment
2,210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2006
U.S. locations
3
States / cities
Little Rock, Arkansas • Athens, Georgia • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2012 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Increasing PrEP Use in High-Risk Social Networks of African-American MSM in Underserved Low-Risk Cities

NCT03823209
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Social Network, Brief HIV Prevention Counseling
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
16 Years and older · Male only
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Cleveland, Ohio • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetic Study of the Vaginal Microbicide Agent 1% Tenofovir Gel

NCT00561496
View directory record Official record
Conditions
HIV Infections
Interventions
Tenofovir gel
Drug
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2008 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Not applicable Interventional

RCT of an Integrative Intervention for Non-Treatment-Seeking Meth Users

NCT01926184
View directory record Official record
Conditions
HIV/AIDS, Stimulant Use Disorders
Interventions
Affect Regulation Treatment to Enhance Meth Intervention Success (ARTEMIS), Contingency Management (CM)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2022 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Not applicable Interventional Results available

A Nurse-led Intervention to Extend the HIV Treatment Cascade for Cardiovascular Disease Prevention

NCT03643705
View directory record Official record
Conditions
HIV/AIDS, Hypertension, Hyperlipidemias
Interventions
Multi-component intervention, General prevention education
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Durham, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 4, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Testing an Online Intervention to Improve Parents' Communication With Gay and Bisexual Sons About Sex and HIV

NCT04018573
View directory record Official record
Conditions
HIV Infections
Interventions
PATHS Sexual Communication Toolkit, Parent Support Film
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 4, 2026, 9:24 AM EDT