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Conditions: Contraception, Sexually Transmitted Diseases, Pregnancy
Interventions: Individualized Intervention, Computer-based contraceptive information; Behavioral
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 13 Years to 35 Years · Female only
Enrollment: 550 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2005
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Acquired Immunodeficiency Syndrome, Stress Disorders, Post-Traumatic
Interventions: Questionnaires; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 15 Years to 25 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Stanford, California

Conditions: Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
Interventions: HIV Prevention Decision Support Tool (DST), Standard Counseling; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 45 Years
Enrollment: 189 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Cervical Carcinoma, Human Papillomavirus Infection
Interventions: Biospecimen Collection, Cervical Biopsy, Colposcopy, Electronic Health Record Review, Endocervical Curettage, Excision, HPV Self-Collection, Human Papillomavirus Test, Questionnaire Administration; Procedure · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 25 Years and older · Female only
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 18
States / cities: Birmingham, Alabama • Atlanta, Georgia • Lafayette, Louisiana + 12 more

Conditions: Pneumonia, Pneumocystis Carinii, HIV Infections
Interventions: Pentamidine isethionate; Drug
Lead sponsor: Fisons; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Rochester, New York

Conditions: HIV/AIDS, Menopause, Inflammation Vagina
Interventions: Tenofovir, Emtricitabine; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older · Female only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: HIV Counseling and Testing, HIV Infections
Interventions: HIV educational video; Procedure
Lead sponsor: North Bronx Healthcare Network; Other
Eligibility: 18 Years and older
Enrollment: 408 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Infections, Papillomavirus
Interventions: Cervarix™, Havrix™-based investigational formulation; Biological
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 15 Years to 25 Years · Female only
Enrollment: 18,729 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 50
States / cities: Birmingham, Alabama • Fountain Valley, California • San Diego, California + 39 more

Conditions: HIV Infections
Interventions: POC NAT & Adherence Intervention; Diagnostic Test
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 932 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sexually Transmitted Diseases
Interventions: Doxycycline, Biktarvy; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 59 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Pneumonia, Pneumocystis Carinii, HIV Infections
Interventions: Pentamidine isethionate; Drug
Lead sponsor: Fisons; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Pneumonia, Pneumocystis Carinii, HIV Infections
Interventions: Pentamidine isethionate, Zidovudine; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 12 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 1992
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: HIV Infections, Opioid Use Disorder
Interventions: ID-TOUCH; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pneumonia, Pneumocystis Carinii, HIV Infections
Interventions: Atovaquone, Dapsone; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 13 Years and older
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 1997
U.S. locations: 43
States / cities: Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 30 more

Conditions: Sexual Behavior, Alcohol Consumption, Sexually Transmitted Diseases
Interventions: Knowledge alone, Self-efficacy alone, Perceived benefits alone, Perceived benefits and self-efficacy, Injunctive norms, Injunctive norms and self-efficacy, Injunctive norms and perceived benefits, Injunctive norms, perceived benefits, and self-efficacy, Descriptive norms alone, Descriptive norms and self-efficacy, Descriptive norms and perceived benefits, Descriptive norms,perceived benefits,self-efficacy, Descriptive and injunctive norms, Descriptive norms, injunctive norms,self-efficacy, Descriptive and injunctive norms, benefits, Descriptive and injunctive norms, benefits,efficacy, Expectancies alone, Expectancies and self-efficacy, Expectancies and Perceived Benefits, Expectancies, perceived benefits, self-efficacy, Expectancies and injunctive norms, Expectancies, injunctive norms, and self-efficacy, Expectancies, injunctive norms, benefits, Expectancies, injunctive norms, benefits, efficacy, Expectancies and descriptive norms, Expectancies, descriptive norms, and self-efficacy, Expectancies, descriptive norms, and benefits, Expectancies,descriptive norms, benefits, efficacy, Expectancies, descriptive and injunctive norms, Expectancies, descr& injun norms, efficacy, Expectancies, desc & injun norms, benefits, Expectancies,desc & injun norms,benefits,efficacy; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 3,997 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 4
States / cities: Fresno, California • Carbondale, Illinois • Greensboro, North Carolina + 1 more

Conditions: HIV/AIDS
Interventions: Family-Based HIV prevention, Adolescent Only Health Promotion; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 13 Years to 18 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: HIV Seropositivity, Pregnancy, High-Risk
Interventions: PrEP, Counseling on timed condomless sex, ART and PrEP adherence; Drug · Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 49 Years
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Human Immunodeficiency Virus
Interventions: Navigators (peer navigator) training, delayed-intervention; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older · Male only
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: HIV, HIV Infections
Interventions: 1-sided messages, 2-sided messages; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 19 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 4
States / cities: San Francisco, California • New Orleans, Louisiana • Baltimore, Maryland + 1 more

Conditions: Healthy Subject, Human Papillomavirus Infection
Interventions: carrageenan-containing gel, Placebo, Laboratory Biomarker Analysis, Questionnaire Administration; Drug · Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 19 Years to 35 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: HIV, Sexually Transmitted Diseases, HIV Infections
Interventions: DVD 1, DVD 2; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 16 Years and older
Enrollment: 1,010 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Gonorrhea, Chlamydia, Syphilis, Sexually Transmitted Infections (STIs)
Interventions: Doxycycline hyclate delayed released 200 mg, Doxycycline hyclate delayed released 200 mg weekly, Per standard of care with quarterly STI testing/treatment and sexual health counseling; Drug · Other
Lead sponsor: Westat; Other
Eligibility: 13 Years to 29 Years · Female only
Enrollment: 760 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 13
States / cities: Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 10 more

Conditions: HIV Infections, HIV Wasting Syndrome
Interventions: Multivitamin and mineral supplements, Peptamen, NuBasics; Dietary Supplement
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 13 Years and older
Enrollment: 536 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1996 – 1998
U.S. locations: 17
States / cities: San Francisco, California • Denver, Colorado • Washington D.C., District of Columbia + 11 more

Conditions: HIV/AIDS
Interventions: PrEP@Home System, Standard of Care; Behavioral · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 49 Years · Male only
Enrollment: 318 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 5
States / cities: Atlanta, Georgia • Boston, Massachusetts • Jackson, Mississippi + 2 more

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Stage Matched Intervention to Increase Dual Method Use

HIV Prevention and Care of Psychological Trauma in Vulnerable Rwandan Youth

The OPENS Trial: Offering Women PrEP (Aim 1)

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

An Open Label Study to Evaluate the Long-Term Safety and Effectiveness of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients

Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract

An Effective Alternative to the Standard Referral System for HIV Testing in the Emergency Department During Off Hour Tours: A Randomized Trial

Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18

Improving HIV Diagnosis, Linkage to Care, and Prevention Services With HIV Point-of-Care Nucleic Acid Tests

Combo-PEP: Multipurpose Prevention of Post-Exposure Prophylaxis Regimens

A Double-Blind Study To Evaluate the Long-Term Safety and Effectiveness of 60 mg Versus 120 mg of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients

A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia

Infectious Disease (ID) Testing OUtreach in Carceral Hubs

A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides

Engineering an Online STI Prevention Program

Project RAP: Family-based HIV Prevention in the Juvenile Drug Court

Safer Conception Intervention for HIV-1 Serodiscordant Couples

Medical Mistrust Among Hispanic/Latino Gay, Bisexual and Other Men Who Have Sex With Men (HLMSM)

Preventative Misconception Intervention

Carrageenan-Containing Gel in Reducing the Rate of HPV Infection in Healthy Participants

Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic

Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections

A Comparison of Two Caloric Supplements in the Prevention of Weight Loss in Patients With AIDS Who Take Daily Multivitamin and Mineral Supplements

Pre-exposure Prophylaxis (PrEP) at Home