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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Sacral Disorder Clear all
Terminated Phase 2Phase 3 Interventional Results available

Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation

NCT02163187
View directory record Official record
Conditions
Rectal Cancer, for Bowel Dysfunction Following Surgery for Rectal Cancers
Interventions
Implantation of the InterStimTM, MSK BFI questionnaires, The Low Anterior Resection Score (LARS) questionnaires, The EuroQOL5D questionnaires, The Fecal incontinence Quality of Life Scale (FIQOL) questionnaires
Device · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 21, 2026, 12:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

UNGF Assessment in Patients With Detrusor Overactivity Undergoing Sacral Neuromodulation

NCT01850706
View directory record Official record
Conditions
Detrusor Overactivity
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy

NCT00564083
View directory record Official record
Conditions
Uterine Prolapse
Interventions
sacral colpopexy
Procedure
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 21, 2011 · Synced Sep 21, 2026, 12:20 AM EDT
Completed No phase listed Observational

Sacral Neuromodulation and the Microbiome

NCT02833402
View directory record Official record
Conditions
Urgency Urinary Incontinence
Interventions
InterStim Therapy
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6

NCT03058289
View directory record Official record
Conditions
Breast Cancer, Head and Neck Cancer, Squamous Cell Carcinoma, Lymphoma, Pancreatic Cancer, Liver Cancer, Colon Cancer, Lung Cancer, Bile Duct Cancer, Chordoma of Sacrum, Sarcoma
Interventions
INT230-6, anti-PD-1 antibody, anti-CTLA-4 antibody
Drug · Biological
Lead sponsor
Intensity Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
7
States / cities
Los Angeles, California • Newport Beach, California • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 21, 2026, 12:20 AM EDT
Terminated Not applicable Interventional Results available

Sacral Nerve Stimulation in Improving Bladder Function After Acute Traumatic Spinal Cord Injury

NCT03083366
View directory record Official record
Conditions
Spinal Cord Injury, Acute, Neurogenic Bladder, Incontinence, Urinary Tract Infections
Interventions
PrimeAdvanced Surescan 97702 Neurostimulator - Medtronic (Minneapolis, MN)
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Downey, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Phase 4 Interventional

Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy

NCT00934999
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Burch urethropexy, Synthetic mid-urethral sling (TVT)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Phase 3 Interventional

Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy

NCT00159705
View directory record Official record
Conditions
Radiculopathy
Interventions
pregabalin
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
13
States / cities
Phoenix, Arizona • Denver, Colorado • Plantation, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Not applicable Interventional Results available

Cycling Versus Continuous Mode in Neuromodulator Programming

NCT02551822
View directory record Official record
Conditions
Urinary Incontinence, Urge
Interventions
sacral neuromodulator
Device
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Sep 21, 2026, 12:20 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Trial to Determine Which of Two Surgical Techniques Works Better to Correct Vaginal Bulging

NCT00988975
View directory record Official record
Conditions
Rectocele
Interventions
Insertion of pelvicol graft
Procedure
Lead sponsor
Urogynecology Associates, Indiana
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 1, 2009 · Synced Sep 21, 2026, 12:20 AM EDT
Completed No phase listed Observational

Vaginal Electrical Stimulation Versus Neuromodulation

NCT01525485
View directory record Official record
Conditions
Refractory Overactive Bladder
Interventions
Not listed
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 99 Years · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laparoscopic Versus Robotic Assisted Laparoscopic Sacrocolpopexy for Vaginal Prolapse

NCT00551993
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
robotic laparoscopic sacrocolpopexy, Laparoscopic Sacral Colpopexy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Sep 21, 2026, 12:20 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cycling Study With the Axonics System

NCT05543382
View directory record Official record
Conditions
Overactive Bladder Syndrome, Urinary Urge Incontinence, Sacral Neuromodulation
Interventions
Axonics System
Device
Lead sponsor
Axonics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
6
States / cities
Naples, Florida • New Orleans, Louisiana • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 21, 2026, 12:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction

NCT01320631
View directory record Official record
Conditions
Sacral Colpopexy, Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 21, 2026, 12:20 AM EDT
Terminated Not applicable Interventional

Ultrasound Image Fusion for Placement of Sacral Quadripolar Leads

NCT01054534
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Placement of interstim lead
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 90 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 12, 2015 · Synced Sep 21, 2026, 12:20 AM EDT
Completed No phase listed Observational

Combined Anticholinergic Medication and Sacral Neuromodulation to Treat Refractory Overactive Bladder

NCT01047046
View directory record Official record
Conditions
Overactive Bladder
Interventions
Retrospective chart review
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2010 · Synced Sep 21, 2026, 12:20 AM EDT
Recruiting No phase listed Observational

Axonics R20 Post-Market Clinical Follow-up (PMCF) Study for the Indication of Fecal Incontinence

NCT07499258
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Axonics SNM System INS Model 5101 (R20)
Device
Lead sponsor
Axonics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
New York, New York • Nashville, Tennessee • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Early Phase 1 Interventional Results available

High Frequency SARS for Neurogenic Bladder and Bowel Emptying

NCT05214378
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Finetech-Brindley Sacral Anterior Roots Stimulation System
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Syracuse, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Phase 3 Interventional Results available

Refractory Overactive Bladder: Sacral NEuromodulation v. BoTulinum Toxin Assessment (ROSETTA)

NCT01502956
View directory record Official record
Conditions
Urinary Incontinence, Urge
Interventions
InterStim® device, Botox® injection
Device · Drug
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
9
States / cities
Birmingham, Alabama • La Jolla, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Sep 21, 2026, 12:20 AM EDT
Active, not recruiting Not applicable Interventional Results available

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design

NCT02676973
View directory record Official record
Conditions
Visceral Prolapse
Interventions
Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 21, 2026, 12:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Robotic Assisted Laparoscopic Sacral Colpopexy Using Alyte Mesh

NCT01320644
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence, Mesh Erosion
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
21 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Sep 21, 2026, 12:20 AM EDT
Completed Phase 4 Interventional Results available

Wound Management for Sacral Pressure Ulcers With Necrotic Tissue

NCT02224638
View directory record Official record
Conditions
Pressure Ulcers
Interventions
TheraHoney HD, SkinTegrity
Device
Lead sponsor
Medline Industries
Industry
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 21, 2026, 12:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Percutaneous Nerve Evaluation Trial Time

NCT06226220
View directory record Official record
Conditions
Urge Incontinence, Urgency-frequency Syndrome, Overactive Bladder
Interventions
Sacral neuromodulation
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 21, 2026, 12:20 AM EDT
Terminated Not applicable Interventional

Sacral Fracture Fusion/Fixation for Rapid Rehabilitation

NCT05426356
View directory record Official record
Conditions
Fracture;Pelvis, Sacral Fracture, Sacroiliac; Fusion, Fragility Fracture, Insufficiency Fractures, Osteoporosis
Interventions
Surgical Intervention, Non-Surgical Management
Device · Other
Lead sponsor
SI-BONE, Inc.
Industry
Eligibility
60 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Chicago, Illinois • Lincoln, Nebraska • Livingston, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 21, 2026, 12:20 AM EDT