- Conditions
- Elevated Intracranial Pressure
- Interventions
- hypertonic saline, Mannitol
- Drug
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 25–48
of 57
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Pain
- Interventions
- Hypertonic Saline, Normal Saline
- Drug · Other
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 4 Years to 17 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Acute Lung Injury, Adult Respiratory Distress Syndrome
- Interventions
- Nebulized hypertonic saline
- Drug
- Lead sponsor
- Denver Health and Hospital Authority
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 1
- States / cities
- Denver, Colorado
- Conditions
- Bronchiolitis
- Interventions
- 3% sodium chloride, 0.9% sodium chloride
- Drug
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- Up to 12 Months
- Enrollment
- 227 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Primary Ciliary Dyskinesia, PCD
- Interventions
- Exercise, HS pretreatment with Exercise
- Behavioral · Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Cystic Fibrosis
- Interventions
- 7% Hypertonic Saline (HS), 0.9% Isotonic Saline (IS)
- Drug
- Lead sponsor
- CF Therapeutics Development Network Coordinating Center
- Network
- Eligibility
- 4 Months to 59 Months
- Enrollment
- 321 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 28
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Palo Alto, California + 24 more
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Chronic Bronchitis
- Interventions
- Inhaled 7% HS (NaCl) home treatment
- Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Healthy Subjects
- Interventions
- Hypertonic Saline
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Congestive Heart Failure, Renal Insufficiency
- Interventions
- furosemide and hypertonic saline solution, furosemide
- Drug
- Lead sponsor
- Aspirus Heart and Vascular Institute-Research and Education
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Wausau, Wisconsin
- Conditions
- Stage IB Melanoma, Stage IIA Melanoma, Stage IIB Melanoma, Stage IIC Melanoma
- Interventions
- sargramostim, sentinel lymph node biopsy, laboratory biomarker analysis, hypertonic saline
- Biological · Procedure · Other
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Head Injury, Minor, Pediatric, Emergency Department Patient
- Interventions
- Hypertonic Saline ( 3% Sodium Chloride Saline), Normal Saline (0.9% NaCl)
- Other
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 8 Years to 17 Years
- Enrollment
- 74 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- COPD, Chronic Bronchitis
- Interventions
- tPAD, 7% hypertonic saline (510K approved as a device)
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 40 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Low Back Pain
- Interventions
- Adhesiolysis
- Procedure
- Lead sponsor
- Pain Management Center of Paducah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Paducah, Kentucky
- Conditions
- Scoliosis Idiopathic, Scoliosis;Congenital
- Interventions
- Normosol-R, buffered 2% hypertonic saline
- Drug
- Lead sponsor
- Joseph D. Tobias
- Other
- Eligibility
- 10 Years to 25 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Cystic Fibrosis
- Interventions
- 7% NaCl, Amiloride HCl
- Drug
- Lead sponsor
- University of North Carolina
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2004
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Chronic Rhinosinusitis (Diagnosis)
- Interventions
- Isotonic saline, Hypertonic Nasal Wash, Fluticasone Propionate
- Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Cystic Fibrosis
- Interventions
- Not listed
- Lead sponsor
- Nicole Hamblett
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 987 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 80
- States / cities
- Birmingham, Alabama • Anchorage, Alaska • Tucson, Arizona + 69 more
- Conditions
- Brain Concussion, Post-Concussion Symptoms
- Interventions
- 3% Hypertonic saline, Placebo
- Drug
- Lead sponsor
- Rady Children's Hospital, San Diego
- Other
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Cystic Fibrosis
- Interventions
- Xylitol, Hypertonic saline
- Drug
- Lead sponsor
- Joseph Zabner
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 2
- States / cities
- Chicago, Illinois
- Conditions
- Cystic Fibrosis
- Interventions
- Active Treatment Group 7% Hypertonic Saline, Control Group 0.9% Isotonic Saline
- Drug
- Lead sponsor
- University of Washington, the Collaborative Health Studies Coordinating Center
- Other
- Eligibility
- 3 Years to 5 Years
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 7
- States / cities
- Aurora, Colorado • Indianapolis, Indiana • St Louis, Missouri + 4 more
- Conditions
- Cystic Fibrosis
- Interventions
- Hypertonic Saline, Placebo
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 5 Years to 12 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Congestive Heart Failure, Renal Insufficiency
- Interventions
- Hypertonic saline, then oral sodium chloride, Normal saline, then oral placebo capsule
- Drug
- Lead sponsor
- Barnes-Jewish Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Respiratory Failure
- Interventions
- Hypertonic saline (3%), Placebo (0.9% saline)
- Drug
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Asthma
- Interventions
- Montelukast
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts