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ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:33 PM EDT

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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Scar Formation, Autologous Fat Grafting
Interventions
Autologous Fat Grafting, No intervention
Procedure · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Syndactyly
Interventions
Hyalomatrix, Skin graft
Device · Other
Lead sponsor
Gillette Children's Specialty Healthcare
Other
Eligibility
Up to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Saint Paul, Minnesota
Recruiting No phase listed Observational

Genetic Analysis of Keloids

NCT01619553
Conditions
Keloid
Interventions
Not listed
Lead sponsor
UConn Health
Other
Eligibility
Not listed
Enrollment
7,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2030
U.S. locations
1
States / cities
Farmington, Connecticut
Completed No phase listed Observational Accepts healthy volunteers

Study of the Composition of Dental Plaque

NCT00001726
Conditions
Dental Caries, Dental Plaque, Periodontal Disease
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Keloid, Scar, Incision, Excision Margin
Interventions
AIV001
Drug
Lead sponsor
AiViva BioPharma, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Encinitas, California • Coral Gables, Florida • Austin, Texas + 1 more
Completed Not applicable Interventional Results available

A Study of a Novel Silicone Dressing to Minimize Scar Formation

NCT01399099
Conditions
Hypertrophic
Interventions
embrace device
Device
Lead sponsor
Neodyne Biosciences, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
13
States / cities
Atherton, California • Bakersfield, California • Danville, California + 10 more
Conditions
Scar Formation
Interventions
GBT009, Placebo
Biological
Lead sponsor
Garnet BioTherapeutics, Inc.
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Chicago, Illinois • Rochester, New York
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Seprafilm® Adhesion Barrier and Cesarean Delivery

NCT00565643
Conditions
Adhesions, Cesarean Section, Delivery, Obstetric
Interventions
modified sodium hyaluronic acid and carboxymethylcellulose, Placebo
Device
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
753 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
3
States / cities
Mineola, New York • Stony Brook, New York • Allentown, Pennsylvania
Conditions
Scars
Interventions
Treatment of 1/2 of skin graft with pulsed-dye laser
Device
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
9 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization

NCT05478551
Conditions
Scar, Hypertrophic Scar
Interventions
Botulinum Toxin, Normal saline
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
ACL Injury, ACL Reconstruction, Scar Formation
Interventions
Losartan, Placebo
Drug · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Burns, Wound of Skin, Skin Wound
Interventions
Amnion Membrane Powder, SOC Wound Covering
Drug · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Terminated Phase 1Phase 2 Interventional Results available

Hypertrophic Scar Prevention by Novel Topical Gel Application

NCT03403621
Conditions
Hypertrophic Scar
Interventions
Pentamidine Isethionate, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Adhesion Formation After Primary Cesarean Delivery
Interventions
Seprafilm®, Control
Device · Other
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Abington, Pennsylvania
Conditions
Scar, Hypertrophic Scar, Mammary Disorder
Interventions
Botulinum Toxins, Normal saline
Drug · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Wound of Skin, Abdominal Wound
Interventions
MRG-001, Saline
Drug
Lead sponsor
MedRegen LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Failed Back Surgery Syndrome, Postlaminectomy Syndrome, Postdiscectomy Epidural Fibrosis
Interventions
Lumbar nerve root decompression, Preoperative low-dose external beam radiation
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Follow up to Acute Wound Scar Study
Interventions
Santyl
Biological
Lead sponsor
Healthpoint
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Completed No phase listed Observational Accepts healthy volunteers

HISTOACRYL: A Study of Its Efficacy in Final Scar Formation

NCT00890578
Conditions
Surgical Incisions
Interventions
adhesive to suture
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Cicatrix, Scar Prevention
Interventions
RXI-109, Placebo
Drug
Lead sponsor
RXi Pharmaceuticals, Corp.
Industry
Eligibility
21 Years to 50 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Not listed Not applicable Interventional Accepts healthy volunteers

Fractional Radiofrequency for Reduction of Surgical Scar Formation

NCT05897723
Conditions
Surgical Incision
Interventions
Fractional Radiofrequency
Device
Lead sponsor
Venus Concept
Industry
Eligibility
21 Years to 75 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Acne Vulgaris
Interventions
Trifarotene Cream, Trifarotene Vehicle Cream
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
17 Years to 35 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
15
States / cities
Scottsdale, Arizona • Fort Smith, Arkansas • Santa Monica, California + 12 more
Terminated Not applicable Interventional Results available

Stoma Closure and Reinforcement Trial ll

NCT04916067
Conditions
Ileostomy - Stoma, Inflammatory Bowel Diseases
Interventions
Mesh Implantation
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Conditions
Brow Ptosis, Facial Scarring
Interventions
5-Fluorouracil, Normal Saline Flush, 0.9% Injectable Solution
Drug
Lead sponsor
Eyelid and Facial Consultants
Other
Eligibility
40 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Houma, Louisiana • New Orleans, Louisiana