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ClinicalTrials.gov public records Last synced Oct 25, 2026, 10:17 PM EDT

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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Scarring Alopecia Clear all
Completed Phase 4 Interventional Results available

Apremilast in the Treatment of Central Centrifugal Cicatricial Alopecia (CCCA)

NCT03521687
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia
Interventions
Apremilast
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 25, 2026, 10:17 PM EDT
Active, not recruiting Not applicable Interventional

Efficacy and Safety of TargetCool + Benev Exosomes in Patients With Hair Thinning

NCT06999408
View directory record Official record
Conditions
Hair Diseases, Alopecia, Hair Thinning
Interventions
Scalp tattoo, Canfield HairMetrix®, TargetCool, Microneedle-facilitated lidocaine application
Device
Lead sponsor
Recens Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Not listed Phase 4 Interventional

Safety and Efficacy of Clobetasol Propionate 0.05% E Foam in Alopecia

NCT01111981
View directory record Official record
Conditions
Alopecia
Interventions
Clobetasol Propionate 0.05% Emollient Foam
Drug
Lead sponsor
Callender Center for Clinical Research
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Mitchellville, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 28, 2010 · Synced Oct 25, 2026, 10:17 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

PAI-1 Expression in Non-scarring Hair Loss

NCT02548689
View directory record Official record
Conditions
Androgenetic Alopecia, Telogen Effluvium, Alopecia Areata
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Phase 2 Interventional

Baricitinib for Central Centrifugal Cicatricial Alopecia in Adults of African Descent

NCT07843732
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia
Interventions
Baricitinib
Drug
Lead sponsor
Raven Clinical Research
Network
Eligibility
18 Years to 75 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Marriottsville, Maryland • Fairfax, Virginia • McLean, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Active, not recruiting Early Phase 1 Interventional

Azelaic Acid as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA)

NCT05416333
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia
Interventions
azelaic acid, usual medication for CCCA
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Recruiting Phase 4 Interventional

Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study

NCT04207931
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia (CCCA)
Interventions
Topical steroid class I-II, Triamcinolone Acetonide, Doxycyline, Minoxidil
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-Ablative Laser to Treat Scarring Alopecia With Hair Follicle Gene Expression Analysis

NCT06946550
View directory record Official record
Conditions
Scarring Alopecia
Interventions
1470nm non-ablative fractional laser
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Elmsford, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 25, 2026, 10:17 PM EDT
Not yet recruiting Phase 4 Interventional

Effect of Platelet-Rich Plasma Versus Placebo in the Treatment of Central Centrifugal Cicatricial Alopecia

NCT06998433
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia
Interventions
Platelet-Rich Plasma (PRP) Injections, Saline
Biological · Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Phase 2 Interventional Results available

Dual JAK1/TYK2 Inhibitor for Cicatricial Alopecia

NCT05076006
View directory record Official record
Conditions
Cicatricial Alopecia
Interventions
PF-06700841, Placebo
Drug
Lead sponsor
Emma Guttman
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Withdrawn Early Phase 1 Interventional

Calcipotriol as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA)

NCT05416320
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia
Interventions
Calcipotriol, Subject's already prescribed drug
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 25, 2026, 10:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia

NCT00691769
View directory record Official record
Conditions
Central Centrifugal Scarring Alopecia, Lichen Planopilaris, Discoid Lupus Erythematosus
Interventions
Not listed
Lead sponsor
Wake Forest University
Other
Eligibility
30 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2018 · Synced Oct 25, 2026, 10:17 PM EDT
Recruiting Phase 2 Interventional

Tirzepatide for Treatment of CCCA

NCT07734870
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia (CCCA)
Interventions
Tirzepatide
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Early Phase 1 Interventional Results available

Study to Determine Effect of Gentle Wounding to Stimulate Hair Follicle Neogenesis

NCT03491267
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia (CCCA)
Interventions
Retinoic acid, Laser, Sham treatment, Sham treatment
Drug · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Recruiting Phase 2 Interventional

Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen Planopilaris

NCT07487948
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia, Lichen Planopilaris
Interventions
Delgocitinib
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Phase 2 Interventional Results available

Ritlecitinib for Cicatricial Alopecia

NCT05549934
View directory record Official record
Conditions
Cicatricial Alopecia
Interventions
PF-06651600
Drug
Lead sponsor
Emma Guttman
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy Evaluation of the Mosaic Ultra Device

NCT06117293
View directory record Official record
Conditions
Skin Texture Disorder, Photoaging, Wrinkle, Scar, Stretch Mark, Acne Vulgaris, Hair Loss
Interventions
Mosaic
Device
Lead sponsor
CynosureLutronic
Industry
Eligibility
18 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
3
States / cities
Lincolnshire, Illinois • Billerica, Massachusetts • Peabody, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Platelet Rich Plasma on Non-scarring Alopecia

NCT03689452
View directory record Official record
Conditions
Androgenetic Alopecia, Alopecia
Interventions
Platelet Rich Plasma, Normal saline
Device · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2020 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Follicular Revival in Fibrosing Alopecia: Evaluating Use of Micro-needling

NCT04342091
View directory record Official record
Conditions
Fibrosing Alopecia, Frontal Fibrosing Alopecia, Central Centrifugal Cicatricial Alopecia
Interventions
SOL Nova Device
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 25, 2026, 10:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

1470nm Laser for the Treatment of Androgenetic Alopecia and Scarring Alopecia

NCT05460611
View directory record Official record
Conditions
Scarring Alopecia, Androgenetic Alopecia
Interventions
Sciton HALO 1470nm Non-ablative laser
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Elmsford, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pain Outcomes Following Intralesional Corticosteroid Injections

NCT03630198
View directory record Official record
Conditions
Keloid, Alopecia Areata, Acne, Hypertrophic Scar, Epidermal Inclusion Cyst, Frontal Fibrosing Alopecia, Lichen Plano-Pilaris, Keratoacanthoma, Plaque Psoriasis, Lichen Simplex Chronicus, Prurigo Nodularis, Nummular Eczema, Granuloma Annulare, Morphea, Lichen Planus
Interventions
Corticosteroid with lidocaine, Corticosteroid with normal saline
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
12 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 25, 2026, 10:17 PM EDT
Recruiting Not applicable Interventional

A Pilot Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia

NCT04764331
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia
Interventions
Revian Red All LED cap
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 25, 2026, 10:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Barriers to Care and QOL for CCCA Patients

NCT03044782
View directory record Official record
Conditions
Scarring Alopecia, Central Centrifugal Cicatricial Alopecia, Central Centrifugal Scarring Alopecia
Interventions
53-Item Survey
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Oct 25, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

A Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia

NCT05759338
View directory record Official record
Conditions
Central Centrifugal Cicatricial Alopecia
Interventions
Revian Red All LED cap
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 25, 2026, 10:17 PM EDT