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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:30 AM EDT

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Showing 337–360 of 408 matching trials from the live ClinicalTrials.gov search.
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization

NCT05478551
Conditions
Scar, Hypertrophic Scar
Interventions
Botulinum Toxin, Normal saline
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Keloid
Interventions
Botulinum toxin type A, Vehicle
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Conditions
Scars
Interventions
Pulsed dye laser treatment, CO2 laser treatment, Combined PDL and CO2 laser treatment, Split PDL and CO2 Laser treatment
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Englewood, Colorado • New York, New York
Conditions
Scars
Interventions
Cautery vs Active Control Arm (Scalpel)
Procedure
Lead sponsor
Scott and White Hospital & Clinic
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Temple, Texas
Conditions
Scar
Interventions
595/1064nm Multiplex Laser, 595nm PDL
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Miami, Florida
Conditions
Adhesions of Soft Tissue
Interventions
Scheduled removal of posterior instrumentation with AmnioFix, Scheduled removal of posterior instrumentation without AmnioFix
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Reston, Virginia
Completed Not applicable Interventional Results available

Treatment of Prepubertal Labial Adhesions

NCT02218463
Conditions
Prepubertal Labial Adhesions
Interventions
Estradiol cream 0.01%, Cetaphil
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
3 Months to 12 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Phimosis, Adhesions
Interventions
stitches and skin adhesive, stitches only
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 7 Years · Male only
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Scar Prevention, Scar Reduction
Interventions
AZX100 Drug Product, Placebo
Drug
Lead sponsor
Capstone Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Austin, Texas
Conditions
Breast Hypertrophy, Abdominal Elastosis, Breast Reconstruction
Interventions
wound closure device (Steri-Strip™)
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Lebanon, New Hampshire
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Vollure for the Correction of Atrophic Facial Scarring

NCT04519515
Conditions
Atrophic Scar
Interventions
Allergan Vollure
Device
Lead sponsor
Siperstein Dermatology
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boynton Beach, Florida
Conditions
Mammoplasty, Scarring, Scar, Breast Reconstruction
Interventions
Granexin® gel 100 μM, Granexin® gel 200 μM, Vehicle gel
Drug
Lead sponsor
Xequel Bio, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
11
States / cities
Los Angeles, California • Pasadena, California • Doral, Florida + 8 more
Conditions
Alopecia Areata, Scarring Alopecia
Interventions
tSVF by lipoaspiration, PRP Concentration, Emulsification tSVF, cSVF isolation and concentration, cSVF in Normal Saline IV
Procedure
Lead sponsor
Regeneris Medical
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
3
States / cities
Irvine, California • North Attleboro, Massachusetts • Stevensville, Montana
Completed Not applicable Interventional Results available

Comparison of 1,550 and 755 Laser in a Split-face Trial

NCT03988049
Conditions
Acne Scars - Mixed Atrophic and Hypertrophic
Interventions
1,550 fracionated photothermolysis laser, 755 picosecond laser
Device
Lead sponsor
David Smart
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murray, Utah
Conditions
Surgical Wound
Interventions
Surgical staples, Subcuticular sutures
Procedure
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Cicatrix
Interventions
Juvista (avotermin)
Drug
Lead sponsor
Renovo
Industry
Eligibility
18 Years to 85 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Surgical Incisions
Interventions
Cicatricell Cream
Other
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Toledo, Ohio
Active, not recruiting Not applicable Interventional

CO2 Laser Revision for Burn Related Donor Site Scars

NCT04456127
Conditions
Burn Scar, Scar, Skin Graft Scar
Interventions
Fractional CO2 Laser
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Recruiting Not applicable Interventional Accepts healthy volunteers

1470nm Laser for the Treatment of Androgenetic Alopecia and Scarring Alopecia

NCT05460611
Conditions
Scarring Alopecia, Androgenetic Alopecia
Interventions
Sciton HALO 1470nm Non-ablative laser
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Elmsford, New York
Conditions
Restrictive Burn Scars of Joint Area
Interventions
Autologous Human Fibroblasts (Isolagen TherapyTM), Placebo
Biological
Lead sponsor
Castle Creek Biosciences, LLC.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
3
States / cities
Boston, Massachusetts • East Meadow, New York • Galveston, Texas
Conditions
Alpha1-Antitrypsin Deficiency
Interventions
Fazirsiran Injection, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
20
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 15 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University

NCT02591537
Conditions
Wounds
Interventions
OxyGenesys Dissolved Oxygen Dressing
Device
Lead sponsor
Halyard Health
Industry
Eligibility
21 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Reduction of Hypertrophic Skin Scarring
Interventions
PF-06473871
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
36
States / cities
Irvine, California • La Jolla, California • Walnut Creek, California + 20 more
Conditions
Scar
Interventions
Er:YAG laser
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Miami, Florida